DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gyc76C and CG32305

DIOPT Version :9

Sequence 1:	NP_001163473.1	Gene:	Gyc76C / 8674026	FlyBaseID:	FBgn0266136	Length:	1525	Species:	Drosophila melanogaster
Sequence 2:	NP_728725.2	Gene:	CG32305 / 317967	FlyBaseID:	FBgn0052305	Length:	1164	Species:	Drosophila melanogaster

Alignment Length:	220	Identity:	62/220 - (28%)
Similarity:	112/220 - (50%)	Gaps:	14/220 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   830 KNIMDQMMEMMEKYANNLEDIVTERTRLLCEEKM--KTEDLLHRMLPQSVA-EKLTMGQGVEPVS 891
            :||:.|:  :|:|....||.|:..:.....:|::  :.||......|.... .||.:    ||
  Fly   237 QNIVYQL--VMKKENGLLESILPRKMIRTLQEEICSRIEDQDKNFTPSKAGLRKLFL----EP-- 293

  Fly   892 YDLVTIYFSDIVGFTAMSAESTPLQVVNFLNDLYTVFDRIIRGYDVYKVETIGDAYMVVSGLPIK 956
            |..|:|..:|:|.:|.::......|:|..|:||:..||.........:::.:||:|..|:|:| .
  Fly   294 YPNVSILVADMVNYTHLTTTLEAPQLVEILHDLFVNFDLAANRNRAMRIKFLGDSYNCVAGIP-N 357

  Fly   957 NGDRHAGEIASMALELLHAVKQHRIAHRPNETLKLRIGMHTGPVVAGVVGLTMPRYCLFGDTVNT 1021
            ....||......|||::|..:  .::.|....:.||||:|:|.|.||::|.|..::.::...|:.
  Fly   358 YFPAHASCCVDQALEMIHITQ--GVSSRRELDINLRIGVHSGEVFAGIIGHTKWQFDIWSKDVDI 420

  Fly  1022 ASRMESNGEALKIHISNKCKLALDK 1046
            .:|:||:|....:|:|.:....||:
  Fly   421 TNRLESSGLPGLVHVSQRTLSMLDE 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gyc76C	NP_001163473.1	PBP1_Speract_GC_like	26..445	CDD:107365
		ANF_receptor	48..412	CDD:279440
		PK_GC-A_B	543..827	CDD:270944
		HNOBA	<835..881	CDD:285003	10/48 (21%)
		CYCc	860..1052	CDD:214485	54/190 (28%)
		Guanylate_cyc	887..1074	CDD:278633	48/160 (30%)
CG32305	NP_728725.2	CYCc	251..449	CDD:214485	57/204 (28%)
		Nucleotidyl_cyc_III	292..445	CDD:299850	47/157 (30%)
		CYCc	814..1056	CDD:214485
		Nucleotidyl_cyc_III	845..1081	CDD:299850
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453934
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830