Protein Alignment Gyc76C and gcy-34

DIOPT Version :10

• Sequence 1: NP_001163473.1
• Gene: Gyc76C / 8674026
• FlyBaseID: FBgn0266136
• Length: 1525
• Species: Drosophila melanogaster
• Sequence 2: NP_506319.1
• Gene: gcy-34 / 191656
• WormBaseID: WBGene00001554
• Length: 686
• Species: Caenorhabditis elegans
• Alignment Length: 696
• Identity: 179/696 - (25%)
• Similarity: 289/696 - (41%)
• Gaps: 180/696 - (25%)

  Fly   480 NELCKKDDTHYTSTVAAVVLGVL------LFCSGVITMSIYRKWKIELEIEGLLWKIDPNEIKGY 538
            |......||:......::||.|.      ::...:||.|:...|      :.|:..:.|| :||:
 Worm    40 NHYYSDTDTYVLVDSVSIVLKVTKDQIWEMYGGFLITYSMEIGW------DELVRSMSPN-LKGF 97

  Fly   539 SGN---------EIVSSPSKVSLMSAQSY-------GSRWTNQFVTSTGR------LRGAVVRIK 581
            ..|         .:|...:    :...|:       |:...:.|   |||      ::|.|..:.
 Worm    98 LDNLDSLHYFIDHVVYKAN----LRGPSFRCEENPDGTLMLHYF---TGRPGLYHIVKGVVKEVA 155

  Fly   582 ELKFPRKRDISREIMKEMRLLRELRHDNINSFIGASVEPTRILLV---------TDYCAKGSLYD 637
            :|.|  ..|||  ::.:.|..|.:..:|     |..||...|.|:         :|.....:|..
 Worm   156 KLVF--NLDIS--LVVQGRTQRSVHMNN-----GERVEEHVIFLIKNVEEPRRDSDTSTTSALTS 211

  Fly   638 IIENEDIKLDDLFIASLIHDLIKGMIYIHNSQLVYHGNLKSSNCVVTSRWMLQVTDFGLHELRQC 702
            :..:         ...:|.|.:|..:...:..|.||..|..| |                .|.||
 Worm   212 VEPD---------FGEIIDDNLKVSLQDFSRALPYHFVLDES-C----------------RLVQC 250

  Fly   703 AENESIGEHQHYRNQLWR-APELLRNHIHGSQKGDVYAFAIIMYEIFSRKGP--FGQI-NFEPKE 763
            .:.    .:.|..|:|.: ...:||                 ::||...:.|  |..| ||....
 Worm   251 GDE----LYNHIPNELLQPGTPILR-----------------IFEINRPQIPLDFENICNFINAV 294

  Fly   764 IVDYVKKLPLK-------GEDPFRPEVESI-IEAES---------------------------CP 793
            .|..||..||:       .::....|||:: .|.||                           |.
 Worm   295 FVLQVKTSPLRKKHMNAMTKEEREQEVEAMEEEVESNELTQGCHLKLKGQMMMLSTKKHIIYLCS 359

  Fly   794 DYVLACIRDCWAEDPEERPEFSVIRNRLKKM-RGGKTKNI-------MDQMMEMMEKYANNLEDI 850
            .||.:.         .|..:|.:   ||..| ....|:::       :..:...::..||| |.:
 Worm   360 PYVTSI---------NELMQFGM---RLTAMPLHDATRDLILLNQQRLSDVEVNLQLEANN-EQL 411

  Fly   851 VTERTRLLCEEKMKTEDLLHRMLPQSVAEKLTMGQGVEPVSYDLVTIYFSDIVGFTAMSAESTPL 915
            .| .|..|..|:.||:.:|..|||:.:|::|..|:.:||..|: .|:.|.|:..|..:.....|.
 Worm   412 ET-MTHELEVERQKTDSILKDMLPRKIAKQLLSGEHLEPCEYE-ATVMFCDLPAFQQIIPVCQPK 474

  Fly   916 QVVNFLNDLYTVFDRIIRGYDVYKVETIGDAYMVVSGLPIKNGDRHAGEIASMALELLHAVKQHR 980
            .:|..||:::...|||:....||||||:.|:||.|||:|....: ||..:..:||.::...:.
 Worm   475 NIVKLLNEVFFKLDRIVVLRGVYKVETVSDSYMTVSGIPDYTSE-HAENMCHVALGMMWEARS-- 536

  Fly   981 IAHRPNET-LKLRIGMHTGPVVAGVVGLTMPRYCLFGDTVNTASRMESNGEALKIHISN-KCKLA 1043
            :....|:| ..||||:|:|.::|||||..||||||||:||..||:|||.|.|.||..|: ....|
 Worm   537 VMDPVNKTPFLLRIGLHSGTIIAGVVGTKMPRYCLFGETVTLASQMESLGVAGKIQCSSWTYSKA 601

  Fly  1044 LDKLGGGYITEKRGLVNMKGKGDVVTWWLTGANENAIQKKLVDMMD 1089
            ::.  |.:....||.:|:||:|||.|::|.    .:::|.:.::.|
 Worm   602 MET--GRFEFSPRGRINVKGRGDVETYFLM----RSLKKSIWEITD 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc76C	NP_001163473.1	PBP1_SAP_GC-like	26..445	CDD:380593
		PK_GC-A_B	543..827	CDD:270944	67/345 (19%)
		HNOBA	<833..881	CDD:462234	15/47 (32%)
		CYCc	860..1052	CDD:214485	76/193 (39%)
gcy-34	NP_506319.1	HNOB	3..167	CDD:462233	30/144 (21%)
		HNOBA	224..441	CDD:462234	57/268 (21%)
		CYCc	421..609	CDD:214485	76/193 (39%)