DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gyc76C and acy-2

DIOPT Version :9

Sequence 1:	NP_001163473.1	Gene:	Gyc76C / 8674026	FlyBaseID:	FBgn0266136	Length:	1525	Species:	Drosophila melanogaster
Sequence 2:	NP_504553.1	Gene:	acy-2 / 191607	WormBaseID:	WBGene00000069	Length:	1080	Species:	Caenorhabditis elegans

Alignment Length:	237	Identity:	78/237 - (32%)
Similarity:	120/237 - (50%)	Gaps:	38/237 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   844 ANNLEDIVTERTRLLCEEKMK--TEDLLHRMLP--------QSVAEKLTMGQGVE-PVS------ 891
            |..|.:.|..||.|   |.:|  .|.||..::|        :|:.:..:.|..|| |.:
Worm   236 ARKLTEAVYRRTEL---ETLKDRQEQLLLSVIPAYLADQVSKSIIQSSSTGSTVEVPRTGKNNTK 297

  Fly   892 ------------YDLVTIYFSDIVGFTAMSAESTPLQVVNFLNDLYTVFDRIIRGYDVYKVETIG 944
                        :|.|:|.|:|||.||.::|:.|...:|..||:||:.|||..:.....:::.:|
Worm   298 NHKLFHDLHVQVHDNVSILFADIVNFTVLAAQLTAKDLVRTLNELYSKFDRDAQRLQCMRIKFLG 362

  Fly   945 DAYMVVSGLPIKNGDRHAGEIASMALELLHAVKQHRIAHRPNETLKLRIGMHTGPVVAGVVGLTM 1009
            |.|..|||:|: |...||.....|.||:::.:||.|||  ....:.:|||:|||.|:.|::||..
Worm   363 DCYYCVSGMPV-NRPNHADMCVVMGLEMINTIKQVRIA--TGVDVNMRIGVHTGSVLCGIMGLRK 424

  Fly  1010 PRYCLFGDTVNTASRMESNGEALKIHISNKCKLALDKLGGGY 1051
            .::.::.|.|..|:.|||.|....:||:...|   |.|.|.|
Worm   425 WQFDIWSDDVTLANHMESAGVPGAVHITKSTK---DMLLGDY 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gyc76C	NP_001163473.1	PBP1_Speract_GC_like	26..445	CDD:107365
		ANF_receptor	48..412	CDD:279440
		PK_GC-A_B	543..827	CDD:270944
		HNOBA	<835..881	CDD:285003	13/46 (28%)
		CYCc	860..1052	CDD:214485	72/221 (33%)
		Guanylate_cyc	887..1074	CDD:278633	64/184 (35%)
acy-2	NP_504553.1	CYCc	253..463	CDD:214485	70/215 (33%)
		Guanylate_cyc	308..459	CDD:278633	58/156 (37%)
		CYCc	817..1034	CDD:214485
		Guanylate_cyc	840..1054	CDD:278633
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900