Protein Alignment Gyc76C and gcy-32

DIOPT Version :10

• Sequence 1: NP_001163473.1
• Gene: Gyc76C / 8674026
• FlyBaseID: FBgn0266136
• Length: 1525
• Species: Drosophila melanogaster
• Sequence 2: NP_506452.5
• Gene: gcy-32 / 179887
• WormBaseID: WBGene00001552
• Length: 684
• Species: Caenorhabditis elegans
• Alignment Length: 714
• Identity: 178/714 - (24%)
• Similarity: 294/714 - (41%)
• Gaps: 191/714 - (26%)

  Fly   465 SGGEKPADEPMCGFANELCKKDDTHYTSTVAAVVLGVL------LFCSGVITMSIYRKWKIELEI 523
            ||.|...:..|    |......||:......::||.|.      ::...:||.|:...|
 Worm    29 SGFESGKENIM----NHYYSDTDTYVLVDSVSLVLKVTKDQVWEMYGGFLITYSMEIGW------ 83

  Fly   524 EGLLWKIDPNEIKGYSGN---------EIVSSPSKVSLMSAQSY-------GSRWTNQFVTSTGR 572
            :.|:..:.|| :||:..|         .:|...:    :...|:       |:...:.|   |||
 Worm    84 DELVRSMSPN-LKGFLDNLDSLHYFIDHVVYKAN----LRGPSFRCEETPDGTLLLHYF---TGR 140

  Fly   573 ------LRGAVVRIKELKFPRKRDISREIMKEMRLLRELRHDNINSFIGASVEPTRILLVTDYC- 630
                  ::|.|..:.:..|    |:...::.:.|..|.:..:|     |..||...:.|:.:..
 Worm   141 PGLYHIVKGVVKEVAKRVF----DLDITLVVQGRTQRSVHMNN-----GERVEEHVVFLINNLSE 196

  Fly   631 ----AKGSLYDIIENEDIK----LDDLFIASLIHDLIKGMIYIHNSQLVYHGNLKSSNCVVTSRW 687
                ::||...::.:.:..    :||....|| .|..|.        |.||..:..| |
 Worm   197 PRRDSEGSEVSLLTSTNANFPTIVDDTLGISL-DDFSKA--------LPYHFVIDES-C------ 245

  Fly   688 MLQVTDFGLHELRQCAENESIGEHQHYRNQLWR-APELLRNHIHGSQKGDVYAFAIIMYEIFSRK 751
                      :|.||...    .|.|..|:|.: ...:||                 ::||...:
 Worm   246 ----------KLVQCGSE----LHNHIPNELLQPGTPILR-----------------IFEINRPQ 279

  Fly   752 GP--FGQI-NFEPKEIVDYVKKLPLK-------GEDPFRPEVESIIEAES--------------- 791
            .|  |..| ||.....|..||..|||       .::..:.|:|::.|..:
 Worm   280 IPLDFENICNFINAVFVLQVKTSPLKKKHMDAMSQEELKQEMETLDEDATNELTQGHHLKLKGQM 344

  Fly   792 ------------CPDYVLACIRDCWAEDPEERPEFSVIRNRLKKM-RGGKTKNI-------MDQM 836
                        |..||.:.         .|..::.:   ||..| ....|:::       :..:
 Worm   345 MLLASKKHIIYLCSPYVTSI---------NELMQYGM---RLTAMPLHDATRDLILLNQQRLSDV 397

  Fly   837 MEMMEKYANNLEDIVTERTRLLCEEKMKTEDLLHRMLPQSVAEKLTMGQGVEPVSYDLVTIYFSD 901
            ...::..||| |.:.| .||.|..|:.||:.:|..|||:.:|::|..|:.:|...:: .|:.|.|
 Worm   398 EVNLQLEANN-EQLET-MTRELELERQKTDSILKDMLPRRIAQQLLSGEHIEACEHE-ATVMFCD 459

  Fly   902 IVGFTAMSAESTPLQVVNFLNDLYTVFDRI--IRGYDVYKVETIGDAYMVVSGLPIKNGDRHAGE 964
            :..|.....:.:|..:||.||:::...|||  |||  ||||||:.|:||.|||:|....: ||..
 Worm   460 LPAFQQAIPQCSPKDIVNMLNEIFRKLDRIVVIRG--VYKVETVSDSYMAVSGIPDYTPE-HAEN 521

  Fly   965 IASMALELLHAVKQ--HRIAHRPNETLKLRIGMHTGPVVAGVVGLTMPRYCLFGDTVNTASRMES 1027
            :..:||.::...:.  ..::..|   ..||||:|:|.:.|||||...|:|||||:||..||:|||
 Worm   522 MCHVALGMMWEARSVIDPVSKTP---FLLRIGIHSGTITAGVVGTVHPKYCLFGETVTLASQMES 583

  Fly  1028 NGEALKIHISNKCKLALDKL--GGGYITEKRGLVNMKGKGDVVTWWLTGANENAIQKKLVDMMD 1089
            .|.|.||..|   |.|..|.  .|.:....||.:::|.:|...|::||    .:::|.:.:::|
 Worm   584 LGMAGKIQCS---KWAYQKAMETGRFEFSPRGRIDVKQRGLTETYFLT----RSLKKSIWEIID 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc76C	NP_001163473.1	PBP1_SAP_GC-like	26..445	CDD:380593
		PK_GC-A_B	543..827	CDD:270944	63/344 (18%)
		HNOBA	<833..881	CDD:462234	16/47 (34%)
		CYCc	860..1052	CDD:214485	77/197 (39%)
gcy-32	NP_506452.5	HNOB	3..167	CDD:462233	31/159 (19%)
		HNOBA	226..440	CDD:462234	58/274 (21%)
		CYCc	419..608	CDD:214485	77/198 (39%)