Protein Alignment Gyc76C and Gyc32E

DIOPT Version :10

• Sequence 1: NP_001163473.1
• Gene: Gyc76C / 8674026
• FlyBaseID: FBgn0266136
• Length: 1525
• Species: Drosophila melanogaster
• Sequence 2: XP_061515263.1
• Gene: Gyc32E / 1279811
• VectorBaseID: AGAMI1_014500
• Length: 1277
• Species: Anopheles gambiae
• Alignment Length: 1227
• Identity: 489/1227 - (39%)
• Similarity: 691/1227 - (56%)
• Gaps: 161/1227 - (13%)

  Fly     5 PFNLLLLLSVAVR---DC---------------SNHRTVLTVG---------YLTALTGDLKTRQ 42
            |..|..|.|...|   ||               :|..::||.|         |:..|.|.:.::
Mosquito    27 PVELHALASAIARMSCDCPRSSTSSSSVDSFLRANVSSLLTTGTRNRTGDELYVGFLAGYVHSK- 90

  Fly    43 GLAISGALTMALDEVNKDPNLLPNVYLDLRWND---TKGDTVLATKAITEMICDGIATIFGPEGP 104
              .:.|||.:|::.:|.|..|||...|.||..|   .|.......|.:|||..:||....||:..
Mosquito    91 --VVLGALLLAIETINNDSTLLPGKKLRLRAVDIGAQKSLKAFPIKKMTEMRDNGIVVFIGPDET 153

  Fly   105 CYVEAIVSQSRNIPMISYKCAEYRAS---AIPTFARTEPPDTQVVKSLLALLRYYAWNKFSIL-- 164
            |..||:|:.:.|:||||||||:...|   ...:||||.||.|:|.||:.|||....|:.|||:
Mosquito   154 CTSEALVASAWNLPMISYKCADIAVSDKTVYSSFARTLPPATKVSKSVAALLLANNWHCFSIVAS 218

  Fly   165 YEDVWS-PVADLLKDQATKRNMTINH---KQSFIDNRVKCCEQMLDCCRSGYWYQLVQNTMNRTR 225
            ....|| .:|..::.||...|:|:||   ...:|.:::...::::|            ||...||
Mosquito   219 KHPAWSMEIAHAIELQAELNNLTVNHFRFYSDYIPSKIYELQEIVD------------NTYRNTR 271

  Fly   226 IYVFLGAANSLVDFMSSMETAGLFARGEYMVIFVDMMVYSEREA-----------EKYL----RR 275
            :|||:|....:|||:..::...|.:.|:|:||.:|..:|.....           :||:    .:
Mosquito   272 VYVFVGDHIEMVDFVRCLQNRKLLSTGDYIVISIDDEIYDPNMKRNIYQEYSDFYQKYIGNSKDK 336

  Fly   276 VDQITFMSNCHSTENFNQMARSLLVVAST-PPTKDYIQFTKQVQKYSSKPPFNLEIP---RLFVE 336
            ..|.....|....|...:..:|:|.::.. |....|.:...|.:.||.|.||.:.:|   .:|.|
Mosquito   337 HQQNRKRYNYKDQERLQEAFQSVLRISPLFPMNPKYRKLCHQFKLYSRKDPFRVPLPYNRHIFDE 401

  Fly   337 SNFSKFISIYAAYLYDSVKLYAWAVDKMLREETRVLTDDVIFEVASNGTRVIDTIIKNRTYMSIT 401
            ..    :.||.|||||::.:||.|..::||:...|          |:| |:|...|.||:|.||.
Mosquito   402 IQ----VPIYGAYLYDALIIYARAATEVLRDGGDV----------SDG-RLIMRHIFNRSYHSIQ 451

  Fly   402 GSKIKIDQYGDSEGNFSVLA-YKPHKWNNSNNMPCNYHMVPVAYFHQGEEH--------PEYKLI 457
            |..:.||..||:||||||:| .|..|.|||.:|    .|.|||.|..|..:        ||::.:
Mosquito   452 GFDVYIDANGDAEGNFSVIALQKDDKVNNSLHM----SMQPVALFAYGARNATGTGTTLPEFRYL 512

  Fly   458 NGS--IDWPSGGEKPADEPMCGFANELC--KKDDTHYTSTVAAVVLGVLLFCSGVITMSIYRKWK 518
            |.:  |.|.. |..|..||:|||.||.|  |..|..|.:....|:|.:.:|     |:.:::.::
Mosquito   513 NPNRPIMWLK-GRPPLAEPVCGFYNEKCRPKAKDWRYITGALVVILFMAIF-----TIILFKHYR 571

  Fly   519 IELEIEGLLWKIDPNEIKGYSGNEIVSSPS-------KVSLMSAQSY----GSRWTNQFVTSTGR 572
            .|..:..||||:|..::      .:::||.       :.:|:..||.    ......:..|:.|.
Mosquito   572 YEQTLACLLWKVDMKDV------ILITSPDALYNNELRKNLVCQQSIMVNSAGDVNKRAYTTIGL 630

  Fly   573 LRGAVVRIKELKFPRKRDISREIMKEMRLLRELRHDNINSFIGASVEPTRILLVTDYCAKGSLYD 637
            .||.:|.||.| ..|..||:|.|.||::.:||:||:|:.:|:|||::...:.::|.|||:|||.|
Mosquito   631 YRGNIVAIKYL-HKRTVDITRNIRKELKQMREIRHENLITFVGASIDHGTVSILTSYCARGSLVD 694

  Fly   638 IIENEDIKLDDLFIASLIHDLIKGMIYIHNSQLVYHGNLKSSNCVVTSRWMLQVTDFGLHELRQC 702
            ::.|||:|||.:|::||:.|::||:||:|:|.:..||||:||..::.|||:.|:.||||||.:.|
Mosquito   695 VLSNEDLKLDHMFVSSLVSDIVKGLIYLHDSDVGSHGNLRSSKILIDSRWVAQIADFGLHEFKSC 759

  Fly   703 AENESIGEHQHYRNQLWRAPELLRN---HIHGSQKGDVYAFAIIMYEIFSRKGPFGQINFEPKEI 764
            .|..|..| :..|..||:||||||:   ...|:||||||:|.|::|||..||||:|.:|...::|
Mosquito   760 QEEPSKFE-KELRRSLWKAPELLRDPNCPPKGTQKGDVYSFGIVLYEIIGRKGPWGDLNMSWQDI 823

  Fly   765 VDYVKKLPLKGEDPFRPEVESIIEAESCPDYVLACIRDCWAEDPEERPEFSVIRNRLKKMRGGKT 829
            |..|......|  .|||.:..|    ..|:||:..:..||.||||:||:..::|.:||.|:.|..
Mosquito   824 VARVMSPEEYG--IFRPSLRGI----DAPEYVIQLLHSCWEEDPEDRPDIRLVRVKLKPMQAGLK 882

  Fly   830 KNIMDQMMEMMEKYANNLEDIVTERTRLLCEEKMKTEDLLHRMLPQSVAEKLTMGQGVEPVSYDL 894
            .||.|.|:.:|||||.|||.||.|||..|.|||.|||.||.||||:||||.|..|:.||...:|.
Mosquito   883 PNIFDNMLAIMEKYAYNLEGIVQERTNQLSEEKKKTESLLLRMLPKSVAESLKRGERVEAECFDC 947

  Fly   895 VTIYFSDIVGFTAMSAESTPLQVVNFLNDLYTVFDRIIRGYDVYKVETIGDAYMVVSGLPIKNGD 959
            |||:|||:||||.:.|:|||.:||..||||||..|.||..||||||||||||||||||||::|||
Mosquito   948 VTIFFSDLVGFTELCAQSTPFEVVEMLNDLYTCCDFIISSYDVYKVETIGDAYMVVSGLPLRNGD 1012

  Fly   960 RHAGEIASMALELLHAVKQHRIAHRPNETLKLRIGMHTGPVVAGVVGLTMPRYCLFGDTVNTASR 1024
            ||||||||:||.||:::....|.|||.|.:::|||:|:|..|||||||.||||||||||||||||
Mosquito  1013 RHAGEIASLALHLLNSISNLEIRHRPGEFIQMRIGIHSGQCVAGVVGLKMPRYCLFGDTVNTASR 1077

  Fly  1025 MESNGEALKIHISNKCKLALDKLGGGYITEKRGLVNMKGKGDVVTWWLTGANENAIQKKL----- 1084
            |||||||||||||:.....|.|| |||..|:||::.:||||::.|:||.|.::   ||::
Mosquito  1078 MESNGEALKIHISSITYGLLKKL-GGYKCEERGIIKVKGKGEMRTYWLLGEDD---QKRMDRFGS 1138

  Fly  1085 ---VDMMDMPPPL---------FSRPRKSPKLNPDSRQPSIQAMHFCGTGSRRQSTV 1129
               :..:.:|..|         .|||.....|: |:..|.:|..|...|..::..:|
Mosquito  1139 NDAITSLTIPDLLCTPDQSQTNLSRPSLRRMLS-DATVPMLQTSHQHSTSDQQIPSV 1194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc76C	NP_001163473.1	PBP1_SAP_GC-like	26..445	CDD:380593	151/459 (33%)
		PK_GC-A_B	543..827	CDD:270944	123/297 (41%)
		HNOBA	<833..881	CDD:462234	32/47 (68%)
		CYCc	860..1052	CDD:214485	132/191 (69%)
Gyc32E	XP_061515263.1	None