Protein Alignment Gyc76C and LOC1269328

DIOPT Version :10

• Sequence 1: NP_001163473.1
• Gene: Gyc76C / 8674026
• FlyBaseID: FBgn0266136
• Length: 1525
• Species: Drosophila melanogaster
• Sequence 2: XP_061499691.1
• Gene: LOC1269328 / 1269328
• VectorBaseID: AGAMI1_002187
• Length: 1739
• Species: Anopheles gambiae
• Alignment Length: 1658
• Identity: 448/1658 - (27%)
• Similarity: 688/1658 - (41%)
• Gaps: 403/1658 - (24%)

  Fly    34 LTGDLKTRQGLAISGAL----TMALDEVNKDPNLLPNVYLDLRWNDTKGDTVLATKAITE----- 89
            |..|......||::..|    |:|:|..:     :|:.:     ||:.|..|:...:|..
Mosquito   295 LATDANRALSLALASNLHIPYTIAMDATS-----IPSSF-----NDSNGKVVIICSSINSPQTIS 349

  Fly    90 -------------MICDGIATIFGPEGPCY----------VEAIVSQSRNIPMISYKCAEYRASA 131
                         ::.|.:.|||......|          ...::...||:.:::....::| |.
Mosquito   350 VINQLKQYSRTKILLLDLVGTIFNSNNVLYRRLAENGAEPFGEVLRHRRNLLVLTILTEKFR-SF 413

  Fly   132 IPTFARTEPPDTQVVKSLLALLRYY---------------AWNKFSILYEDVWSPVA-------- 173
            :......:..|.:.:...|..:|..               ..:.|:...:|..:|.|
Mosquito   414 LHRLHGVDLGDYKHISENLLKIRLMDDKLPRDTGNDDDGDGADGFNATTDDAAAPSAYGDEQPAP 478

  Fly   174 -----DLLKDQATKRNMTINHKQSFIDNRVKCCEQMLDCCRSGYWYQLVQNTMNRTRIYVFLGA- 232
                 .||.....:..:.:....:...|..:.|:......:...||:::..|.:..|.....|:
Mosquito   479 VPDLPPLLPPHPPEMLLELLSLATNGTNASESCDFHYLLTQVANWYEILAQTFDTARCQTLFGSY 543

  Fly   233 ------------------------ANSLVDFMSSMETAGLFARGEYMVIFVDMMV--YSEREAEK 271
                                    .|:..|  .::....|.|..:.:..|.|:.:  |....|::
Mosquito   544 CEAGAGHGADSAGDRNLHHPSSSPVNNETD--RALANRSLEATIDEIERFCDLFLASYDRLLADE 606

  Fly   272 YLRRVDQITFMSNCHSTENFNQMARSLLVVASTPPTKDYIQFTKQVQKYSSKPPFNLEIPRLFVE 336
                :..||..|:..||.|   .:.|....|:.|||.|::                     |...
Mosquito   607 ----LSTITTTSSSSSTAN---ASWSWGAEATQPPTTDHL---------------------LMFG 643

  Fly   337 SNFSKFISIYAAYLYDSVKLYAWAVDKMLRE------ETRVLTDDVIFEVASNGTRVIDTIIKNR 395
            .:|         |.:|  .|.|.|.|...|:      ..:...|.|.|:..:...|  .|.:..|
Mosquito   644 EHF---------YFFD--YLLAVAEDAQARDGPGYGPHRKFQFDFVAFDFKNISHR--RTAVMWR 695

  Fly   396 TYMSITGSKIKIDQYGDSEGNFSVLAYKPHKWNNSNNMPCNYHMVPVAYFHQGEEHPEYKLINGS 460
            .::.:..|::...|:                         :.|.||..|...        ::..:
Mosquito   696 PFLILQQSQLHRHQF-------------------------SMHPVPPGYADW--------VVEAT 727

  Fly   461 ID--WPSGGEKPADEPMCGFANELCKKDDTHYTSTVAAVVLGVLLFCSGVITMSIYRKW-----K 518
            ::  |           :||.   ||............|:::|.::|...|....|..:.     |
Mosquito   728 LETIW-----------ICGV---LCWAIVGLVGLIAVAMIVGSIVFSIAVRNYIIKTRLSKGPNK 778

  Fly   519 IELEIEGLLWKID-----------------------------PNEIKGYSG---NEIVSSPSKVS 551
            |.|.....::.:|                             |:.:||..|   |..:.:|:|.|
Mosquito   779 IVLSPSDFVFPVDMRRVDEGIEAMLCCWLQQLQEFGGPEVEKPDLLKGSIGSLKNLGLPAPTKPS 843

  Fly   552 LMSAQSYGSRWTNQFVTSTGRLRGAVVRIKEL-KFPRKRDISREIMKEMRLLRELRHDNINSFIG 615
              |......|.:...:....|..|.:|::||: ......::..:.|..:.:...|||:|||..||
Mosquito   844 --SGSETLIRHSTAAIDHKARYNGDLVQLKEIPSSSASHELKTKAMDLLVMAHGLRHENINPLIG 906

  Fly   616 ASVEPTRILLVTDYCAKGSLYDIIENEDIKLDDLFIASLIHDLIKGMIYIHNSQLVYHGNLKSSN 680
            ...||:|..||.::|::|||.|::..::||||..|..||:.||::||.|:|.|.|..||:|.|.|
Mosquito   907 WLNEPSRTALVFEHCSRGSLQDVLIMDEIKLDWSFRLSLLTDLVRGMRYLHASPLRVHGSLSSRN 971

  Fly   681 CVVTSRWMLQVTDFGL---HELRQCAENESIGEHQHYRNQLWRAPELLRNH----IHGSQKGDVY 738
            |||.:||:|::||:|:   :|.:..|.     ..::.:..||.|||.||:.    ..|:|..|||
Mosquito   972 CVVDARWVLKITDYGMLSFYEAQGIAP-----APRNAKELLWTAPEALRDSRTYPKAGTQPADVY 1031

  Fly   739 AFAIIMYEIFSRKGPFGQINFEPKEIVDYVKKLPLKGEDPFRPEVESIIEAESCPDYVLACIRDC 803
            ||.|||.|:..|..|:..::..|.||:..:||.|        |.:...:...:.|...:..:|.|
Mosquito  1032 AFGIIMQEVVVRGEPYCMLSLTPDEIIAKIKKPP--------PLIRPSVSKGAAPPEAINIMRQC 1088

  Fly   804 WAEDPEERPEFSVIRNRLKKMRGGKTKNIMDQMMEMMEKYANNLEDIVTERTRLLCEEKMKTEDL 868
            |||:||.||:|:.|..|.|::..|:..|.:|.|.:|:|||:||||:::.|||.||..|:.|||.|
Mosquito  1089 WAENPEMRPDFATICERFKQLNHGRKVNFVDTMFQMLEKYSNNLEELIRERTELLDIERKKTEQL 1153

  Fly   869 LHRMLPQSVAEKLTMGQGVEPVSYDLVTIYFSDIVGFTAMSAESTPLQVVNFLNDLYTVFDRIIR 933
            |:||||.||||||.:|..|||..:..||||||||||||.::|..||:|||:.||||||.||..|.
Mosquito  1154 LNRMLPSSVAEKLKLGLAVEPEEFAEVTIYFSDIVGFTTIAAHCTPVQVVDLLNDLYTCFDATIN 1218

  Fly   934 GYDVYKVETIGDAYMVVSGLPIKNGDRHAGEIASMALELLHAVKQHRIAHRPNETLKLRIGMHTG 998
            .|:||||||||||||||||||::..| ||.:||:|||:||......::.|.|...|:||||:|||
Mosquito  1219 AYNVYKVETIGDAYMVVSGLPVRTPD-HAEQIATMALDLLSQSGHFKVRHLPGVPLQLRIGLHTG 1282

  Fly   999 PVVAGVVGLTMPRYCLFGDTVNTASRMESNGEALKIHISNK-CKLALDKLGGGYITEKRGLVNMK 1062
            |..||||||||||||||||||||||||||.|.:.:||:|.: |.| |:| .|||:.|.||.:.:|
Mosquito  1283 PCCAGVVGLTMPRYCLFGDTVNTASRMESTGSSWRIHMSQQTCNL-LEK-AGGYVIEPRGPIEIK 1345

  Fly  1063 GKGDVVTWWLTGANENAIQKKLVDMMDMPPP----------------LF-SRPRKSPKLNPDSRQ 1110
            |||.:.|:||.|       ||..|....|||                || |:.....|:|    .
Mosquito  1346 GKGKMHTYWLLG-------KKGFDKALPPPPPIGESHGLDVAILKHSLFQSQQNHGAKIN----N 1399

  Fly  1111 PSIQAMHFCGTGSRRQSTVPRAMDGESTYSLQGSVRESPRMVSKRD-RDRERPPINGLGAGHFVG 1174
            .|||: :.|.|.:...|..| ::.||   |:...|..:|.:....| ..:::.|.....|.....
Mosquito  1400 ASIQS-NTCSTANHSSSHSP-SVAGE---SIDVKVEITPPVPPSLDPGQQQQQPGQDTAAVLSTS 1459

  Fly  1175 GALLESAQASLSTLNHSETNETNCD--------------MDGG--SGG------------VSGSG 1211
            .::..|:..:..|||..|..:....              .||.  |.|            .|.|.
Mosquito  1460 FSIESSSSNNTFTLNLGEFGQPKASPLPSPQARKLSEVIADGSFLSAGATFDRLNPSPSSASASS 1524

  Fly  1212 SGLVRQPNALHKPLAMVRPHRIISAAQ--LPQLGDNDDDSADTLLRESRSLDPMPMQQLRKRHDR 1274
            :.|.::...|....:....::.:|.::  |.|..::...|.. |..:|.|..|...:.||::.
Mosquito  1525 TRLFKRIEELIDLSSPYNYYKCLSPSENNLSQCTESRYGSYQ-LRSDSCSSKPGSTRFLRRQF-- 1586

  Fly  1275 VKLPPSKLSKNNSRSLDTGVSLISGNPNGEVHSSQLDLDNEMTANPVDATDGYDDELGLLMRHDN 1339
                  .|.|:     |.|.|  ||.......|::..||   |.:.:..              |.
Mosquito  1587 ------SLDKD-----DVGPS--SGGHGAATLSAKATLD---TISSISV--------------DR 1621

  Fly  1340 GQLPALRYSGSFPNAQISIVPTGRSAGGGGGGREGGGSNCAKHLNNNCNGGVNVEDDLESPLLQR 1404
            .||..:....|.|    ||..|..:...|||.::   .:.|.|...:.:...::|...|.||
Mosquito  1622 EQLARMGTLTSIP----SISSTNSATLPGGGQKQ---RSLAMHRQQSASVAQDLEKIEEIPL--- 1676

  Fly  1405 QASLSVPPEEMLAHNKRWHSLEHMDGPGGHGGNSVSYAADIDNRHPGDLDFFSGSSNQHHRSKAA 1469
                  .|:..:        :.|..|.||.||.|.|.::            .....|:..||...
Mosquito  1677 ------SPQSFI--------INHTGGGGGGGGGSSSTSS------------LQSEVNERGRSFRN 1715

  Fly  1470 GGSKLTNWMTNIFKGNGVRSGEARRVGILPSGV 1502
            |.|...|.          .||:..|:.:...|:
Mosquito  1716 GASTAPNG----------HSGKELRLSVEALGL 1738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc76C	NP_001163473.1	PBP1_SAP_GC-like	26..445	CDD:380593	79/503 (16%)
		PK_GC-A_B	543..827	CDD:270944	101/291 (35%)
		HNOBA	<833..881	CDD:462234	29/47 (62%)
		CYCc	860..1052	CDD:214485	123/192 (64%)
LOC1269328	XP_061499691.1	None