DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Gyc76C and ADCY6

DIOPT Version :9

Sequence 1:NP_001163473.1 Gene:Gyc76C / 8674026 FlyBaseID:FBgn0266136 Length:1525 Species:Drosophila melanogaster
Sequence 2:NP_001377760.1 Gene:ADCY6 / 112 HGNCID:237 Length:1168 Species:Homo sapiens


Alignment Length:236 Identity:77/236 - (32%)
Similarity:122/236 - (51%) Gaps:26/236 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly   861 EKMKTED-------LLHRMLPQSVAEKLTMGQGVEPVSY----DLVTIYFSDIVGFT----AMSA 910
            ||.:.|:       |||.:||:.||......:......|    :.|.:.|:.|..|:    .:.|
Human   933 EKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEA 997

  Fly   911 ESTPLQVVNFLNDLYTVFDRII---RGYDVYKVETIGDAYMVVSGLPIKNGDR----HAGEIASM 968
            .:..::.:..||::...||.||   |...:.|::|||..||..|||.....|:    |...:|..
Human   998 NNEGVECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADY 1062

  Fly   969 ALELLHAVKQHRIAHRPNETLKLRIGMHTGPVVAGVVGLTMPRYCLFGDTVNTASRMESNGEALK 1033
            |:.|:..:| |...|..| ..:::||::.|||||||:|...|:|.::|:|||.:|||:|.|...:
Human  1063 AMRLMEQMK-HINEHSFN-NFQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDR 1125

  Fly  1034 IHISNKCKLALDKLGGGYITEKRGLVNMKGKGDVVTWWLTG 1074
            |.::......|  ...||..|.||:|.:||||::.|::|.|
Human  1126 IQVTTDLYQVL--AAKGYQLECRGVVKVKGKGEMTTYFLNG 1164

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gyc76CNP_001163473.1 PBP1_Speract_GC_like 26..445 CDD:107365
ANF_receptor 48..412 CDD:279440
PK_GC-A_B 543..827 CDD:270944
HNOBA <835..881 CDD:285003 10/26 (38%)
CYCc 860..1052 CDD:214485 65/212 (31%)
Guanylate_cyc 887..1074 CDD:278633 66/201 (33%)
ADCY6NP_001377760.1 AC_N <16..368 CDD:318454
Guanylate_cyc 370..554 CDD:306677
DUF1053 582..668 CDD:399378
Guanylate_cyc 970..1164 CDD:306677 66/197 (34%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.