Protein Alignment Gyc76C and npr1

DIOPT Version :10

• Sequence 1: NP_001163473.1
• Gene: Gyc76C / 8674026
• FlyBaseID: FBgn0266136
• Length: 1525
• Species: Drosophila melanogaster
• Sequence 2: XP_031747254.1
• Gene: npr1 / 100492092
• XenbaseID: XB-GENE-970522
• Length: 1053
• Species: Xenopus tropicalis
• Alignment Length: 1137
• Identity: 406/1137 - (35%)
• Similarity: 613/1137 - (53%)
• Gaps: 167/1137 - (14%)

  Fly     8 LLLLLS--VAVRDCSNHRTVLTVGYLTALTGDLKTRQGL-----AISGALTMALDEVNKDPNLLP 65
            :||||:  .|.:..:...:.||:..|..     :|.:|.     .:..|:.||::.:|:||.|||
 Frog     6 VLLLLAGCWACQGVAEGLSNLTMAILLP-----RTNRGYPWAWPRVGPAIHMAIERINRDPALLP 65

  Fly    66 NVYLDLRWNDTK------GDTVLATKAITEMICDGIATIFGPEGPCYVEAIVSQSR---NIPMIS 121
            ::.:...:.|::      .|:.....|:............|| |..|..|.|::..   .:|:|:
 Frog    66 DLRVQTFFGDSEDKDGNCSDSTAPVVAVDLQFTHHPEVFLGP-GCIYTAAPVARFTAHWKVPLIT 129

  Fly   122 YKCAEY----RASAIPTFARTEPPDTQVVKSLLALLRYYAW-NKFSILYEDVWSPVADL------ 175
            ...|.:    ::.......||....|::.:.:..:.:.|.| ::..|:|.|  |.:.|.
 Frog   130 VGAAAFGFNDKSDVYQYTTRTGLIPTKLGQFVGHIHQRYNWSSRAMIVYRD--SSLDDRPCFFTM 192

  Fly   176 --LKDQATKRNMTINHKQSFIDNRVKCCEQMLDCCRSGYWYQLVQNTMNRTRIYVFLGAANSLVD 238
              |..:..|.|:|:...| |.|..:.            .:..|:.:...:.||.......:....
 Frog   193 EGLYMELLKFNLTVLDLQ-FKDKELT------------NYTSLIHDIKQKGRIIYMCCYPDMFRQ 244

  Fly   239 FMSSMETAGLFARGEYMVIFVDM-------MVYSEREAEKYLRRVDQITFMSNCHSTENFNQMAR 296
            .|......|| ..|:|...:||:       .::.:.:...|....|      :..:.|.|..:
 Frog   245 LMIQAWREGL-CSGDYAFFYVDIWGASLQGAIFPDPQRPWYRGDPD------DAKAREAFKAV-- 300

  Fly   297 SLLVVASTPPTKDYIQFTKQVQKYSSKPPFNLEIPRLFVESNFSKFISIYAAYLYDSVKLYAWAV 361
             :::....|...:|.:|...:.:||..|         |.....|..::..:|..:|||.|||.||
 Frog   301 -MIITYKEPDNPEYREFLANLSRYSEAP---------FYYRQESTLMNALSASFHDSVLLYAHAV 355

  Fly   362 DKMLREETRVLTDDVIFEVASNG-----TRVIDTIIKNRTYMSITGSKIKIDQYGDSEGNFSVL- 420
            :     |||           :||     ...:.:.::|:::...:|. :|||..||.|.:||:.
 Frog   356 N-----ETR-----------ANGYSMKNASAVTSYMRNKSFYGASGF-VKIDDNGDRENDFSLWD 403

  Fly   421 AYKPHKWNNSNNMPCNYHMVPVAYFHQGEEHPEYKLINGSIDWPSGGEKPADEPMCGF--ANELC 483
            .|:||            ....:.|.:.|.......|....|:|| |...|.|.|.|||  ::..|
 Frog   404 MYEPH------------GTFQIVYNYNGTLRKIVPLPGREIEWP-GNRIPRDVPPCGFDHSDPKC 455

  Fly   484 KKDDTHYTSTVAAVVLGVLLFCSGVITMS---IYRKWKIELEIEGLLWKIDPNEIKGYSGN---E 542
            ||........::.|:..:||    :||:|   ||||.::|.|:...||:|...:|  ::.|   .
 Frog   456 KKSSFTILEILSIVICFILL----IITVSSIFIYRKLRLEKELAAELWRIRWEDI--HTSNLEKN 514

  Fly   543 IVSSPSKVSL-MSAQSYGSRWTN----QFVTSTGRLRGAVVRIKELKFPRKR-DISREIMKEMRL 601
            :..:.||::| :...:|||..|.    |....|...:|.::.:|.:.  ||| :::|:::.|::.
 Frog   515 LRRAGSKLTLSLRGSNYGSLLTTEGQFQIYAKTAYYKGNIIAVKHIN--RKRIELTRKVLFELKH 577

  Fly   602 LRELRHDNINSFIGASVEPTRILLVTDYCAKGSLYDIIENEDIKLDDLFIASLIHDLIKGMIYIH 666
            :|:::::::..|:|:.::|..|.::|:||.:|||.||:|||.|.||.:|..|||:|::|||:::|
 Frog   578 MRDVQNEHLTRFVGSCIDPPNICILTEYCPRGSLQDILENESITLDWMFRYSLINDIVKGMLFLH 642

  Fly   667 NSQLVYHGNLKSSNCVVTSRWMLQVTDFGLHELRQCAENESIGEHQHYRNQLWRAPELLRNHI-- 729
            ||.:|.|||||||||||.||::|::||:||...|...::|.|  |.::..:||.:|||||...
 Frog   643 NSVIVTHGNLKSSNCVVDSRFVLKITDYGLASFRCSPDSEDI--HAYFAKKLWTSPELLRMETPP 705

  Fly   730 -HGSQKGDVYAFAIIMYEIFSRKGPF--GQINFEPKEIVDYVKKLPLKGEDP-FRPEVESIIEAE 790
             .|:||||||:|.||:.|:..|.|.|  ...::.||||::.|:    ..|.| |||
 Frog   706 PQGTQKGDVYSFGIILQEVALRNGVFYVDNADYSPKEIIERVR----SREKPIFRP--------- 757

  Fly   791 SCPDYVLAC--------IRDCWAEDPEERPEFSVIRNRLKKMRGGKTKNIMDQMMEMMEKYANNL 847
             |.:  |.|        ::.||||||.|||||:.|:.:|:|.....:.||:|.::..||:|||||
 Frog   758 -CTN--LYCHIQELGQLMQRCWAEDPFERPEFNQIKVQLRKFNRESSTNILDNLLSRMEQYANNL 819

  Fly   848 EDIVTERTRLLCEEKMKTEDLLHRMLPQSVAEKLTMGQGVEPVSYDLVTIYFSDIVGFTAMSAES 912
            |::|.:||:...|||.|.|.||:::||.||||:|..|:.|:..::|.|||||||||||||:||||
 Frog   820 EELVEDRTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAES 884

  Fly   913 TPLQVVNFLNDLYTVFDRIIRGYDVYKVETIGDAYMVVSGLPIKNGDRHAGEIASMALELLHAVK 977
            ||:|||..||||||.||.||..:|||||||||||||||||||::||..||.|:|.|:|.||.|||
 Frog   885 TPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHAREVARMSLALLDAVK 949

  Fly   978 QHRIAHRPNETLKLRIGMHTGPVVAGVVGLTMPRYCLFGDTVNTASRMESNGEALKIHISNKCKL 1042
            ..:|.||||:.|:||||:|||||.||||||.|||||||||||||||||||||||||||:|.....
 Frog   950 SFKIRHRPNQQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHVSTATHC 1014

  Fly  1043 ALDKLGGGYITEKRGLVNMKGKGDVVTWWLTG 1074
            .|::. ..::.|.||.|.|||||.|.|:||.|
 Frog  1015 VLEEF-NCFVLELRGDVEMKGKGKVRTYWLQG 1045

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc76C	NP_001163473.1	PBP1_SAP_GC-like	26..445	CDD:380593	92/458 (20%)
		PK_GC-A_B	543..827	CDD:270944	117/303 (39%)
		HNOBA	<833..881	CDD:462234	25/47 (53%)
		CYCc	860..1052	CDD:214485	131/191 (69%)
npr1	XP_031747254.1	PBP1_NPR_A	27..434	CDD:380608	95/475 (20%)
		PK_GC-A_B	525..799	CDD:270944	114/293 (39%)
		HNOBA	<805..853	CDD:462234	25/47 (53%)
		CYCc	832..1017	CDD:214485	130/184 (71%)