DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mtTFB1 and tfb1m

DIOPT Version :9

Sequence 1:	NP_648499.1	Gene:	mtTFB1 / 8674019	FlyBaseID:	FBgn0261381	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	XP_021322908.1	Gene:	tfb1m / 767802	ZFINID:	ZDB-GENE-060929-1010	Length:	354	Species:	Danio rerio

Alignment Length:	320	Identity:	163/320 - (50%)
Similarity:	212/320 - (66%)	Gaps:	12/320 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 SGMRLPPMPTIRELVKLYRLQARKQLSQNFLMDERLTDKIVKSAGRIDPRDLVLEVGPGPGGITR 75
            ||.||||:|||.|::|||.|:|:||||||||:|.|||||||:.||.::... |.||||||||:||
Zfish    13 SGCRLPPLPTIGEIIKLYNLKAQKQLSQNFLLDTRLTDKIVRQAGNLNNAH-VCEVGPGPGGLTR 76

  Fly    76 SILRRHPQRLLLVEKDPRFGETLQLLKECASPLNIQFDIHYDDILRFNIEQHIP--------DTS 132
            |||:.....||:||||.||...||||.| |:|..|:  |...|||.:.:|:..|        |..
Zfish    77 SILKAGAADLLVVEKDMRFIPGLQLLSE-AAPGRIR--IAQGDILAYKLERRFPANITKTWEDDP 138

  Fly   133 QRIHLIGNLPFAISTRLLINWLDDLAARRGAFRRIDTCMTLTFQQEVAERICAPVGGEQRCRLSV 197
            ..:|:||||||.:||.|:|.||:.::.|.|.|....|.:|||||:|||||:.|..|..||.||||
Zfish   139 PNLHIIGNLPFNVSTPLIIKWLEQMSNRTGIFMFGRTRLTLTFQKEVAERLTASTGSRQRSRLSV 203

  Fly   198 MSQVWTEPVMKFTIPGKAFVPKPQVDVGVVKLIPLKRPKTQLPFHLVERVVRHIFSMRQKYCRRG 262
            |:|..|.....|||||:||||||.||||||...||.:|:.|.||.|||::|::.|..|:|:||||
Zfish   204 MAQYLTTVKSCFTIPGQAFVPKPNVDVGVVHFTPLAQPQIQQPFKLVEKIVKNAFQFRRKHCRRG 268

  Fly   263 YGTLLPPEDREEVAEKLFQRAEVQDTLRPFELTVEQCLRLAEVYSEHLVTRPEVAAYDYR 322
            .|.|.|...|:|:.|:|...|:|..||||.|:::.:...||:.||:.......:..||:|
Zfish   269 LGMLFPESQRQELTEELLCSADVDPTLRPTEISISEFRALADAYSKLCNENQGLFDYDFR 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mtTFB1	NP_648499.1	ksgA	18..310	CDD:234708	154/299 (52%)
tfb1m	XP_021322908.1	ksgA	20..315	CDD:234708	154/298 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593709
Domainoid	1	1.000	240	1.000	Domainoid score	I2224
eggNOG	1	0.900	-	-		E1_COG0030
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9343
Inparanoid	1	1.050	295	1.000	Inparanoid score	I2741
OMA	1	1.010	-	-		QHG52847
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006502
OrthoInspector	1	1.000	-	-		oto40467
orthoMCL	1	0.900	-	-		OOG6_105999
Panther	1	1.100	-	-	LDO	PTHR11727
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4149
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.760