DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mtTFB1 and Tfb1m

DIOPT Version :9

Sequence 1:	NP_648499.1	Gene:	mtTFB1 / 8674019	FlyBaseID:	FBgn0261381	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_852139.2	Gene:	Tfb1m / 308140	RGDID:	727795	Length:	345	Species:	Rattus norvegicus

Alignment Length:	318	Identity:	161/318 - (50%)
Similarity:	216/318 - (67%)	Gaps:	14/318 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 RLPPMPTIRELVKLYRLQARKQLSQNFLMDERLTDKIVKSAGRIDPRDL-VLEVGPGPGGITRSI 77
            ||||:|||||::||:.|:|.||||||||:|.|||||||:.||.:  .|: |.|||||||||||||
  Rat    11 RLPPLPTIREIIKLFGLRAAKQLSQNFLLDLRLTDKIVRKAGSL--ADVYVYEVGPGPGGITRSI 73

  Fly    78 LRRHPQRLLLVEKDPRFGETLQLLKECASPLNIQFDIHYDDILRFNIEQHIPDTSQR-------- 134
            |......||:||||.||...||:|.: |:|..::  |.:.|:|.:.||:..||..:|
  Rat    74 LNADIAELLVVEKDTRFIPGLQMLSD-AAPGKLR--IVHGDVLTYKIEKAFPDNIRRQWEDDPPN 135

  Fly   135 IHLIGNLPFAISTRLLINWLDDLAARRGAFRRIDTCMTLTFQQEVAERICAPVGGEQRCRLSVMS 199
            :|:||||||::||.|:|.||::::.:.|.|....|.||||||:|||||:.|..|.:||.|||:|:
  Rat   136 VHIIGNLPFSVSTPLIIKWLENISLKNGPFVYGRTKMTLTFQKEVAERLVATTGSKQRSRLSIMA 200

  Fly   200 QVWTEPVMKFTIPGKAFVPKPQVDVGVVKLIPLKRPKTQLPFHLVERVVRHIFSMRQKYCRRGYG 264
            |........||||||||||||:||||||.|:||.:||.:.||.|||:||:::|..|:|||.||.|
  Rat   201 QYLCNVEHLFTIPGKAFVPKPEVDVGVVHLMPLVQPKIKQPFKLVEKVVQNVFQFRRKYCHRGLG 265

  Fly   265 TLLPPEDREEVAEKLFQRAEVQDTLRPFELTVEQCLRLAEVYSEHLVTRPEVAAYDYR 322
            .|.|...|.|...:|.|.|::..||||..|::.....|.:||.:.....|::.||::|
  Rat   266 MLFPEAQRLESTGRLLQLADIDPTLRPTHLSLMHFKSLCDVYRKMCDEDPQLFAYNFR 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mtTFB1	NP_648499.1	ksgA	18..310	CDD:234708	153/300 (51%)
Tfb1m	NP_852139.2	ksgA	15..310	CDD:234708	153/299 (51%)
Tfb1m	NP_852139.2	S-adenosyl-L-methionine binding. /evidence=ECO:0000250	35..38		2/2 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351904
Domainoid	1	1.000	238	1.000	Domainoid score	I2237
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9343
Inparanoid	1	1.050	291	1.000	Inparanoid score	I2709
OMA	1	1.010	-	-		QHG52847
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006502
OrthoInspector	1	1.000	-	-		oto97137
orthoMCL	1	0.900	-	-		OOG6_105999
Panther	1	1.100	-	-	LDO	PTHR11727
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4149
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.900