DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42542 and SPAC186.05c

DIOPT Version :9

Sequence 1:	NP_001163614.1	Gene:	CG42542 / 8674000	FlyBaseID:	FBgn0260659	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_595023.1	Gene:	SPAC186.05c / 2542574	PomBaseID:	SPAC186.05c	Length:	262	Species:	Schizosaccharomyces pombe

Alignment Length:	433	Identity:	99/433 - (22%)
Similarity:	154/433 - (35%)	Gaps:	180/433 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 LDVQGDLNRPTDLSSLAEKPKDAADRPKTKGTFIDAFTASISVILLTELGDKTFFIAAIMAMRHP 126
            ::|:..||..|.|.||          ..:.|: :.....|||:|:..|||||:|.:.|::|.::.
pombe     2 INVESPLNLETTLGSL----------QFSHGS-VQNIGMSISMIIGCELGDKSFIVTALLAYQYG 55

  Fly   127 RLIVFGGAIAALALMTVLSCAFGMAANFI-PKIYTYYISTALFLIFGLKMLYDGYKMKPTDAQEE 190
            |..||.|:..||..||..:...|.||.|: ||..|:.:...||||||:|||            :|
pombe    56 RASVFFGSYLALFFMTSFAVLVGRAAPFLFPKSITHILGGTLFLIFGVKML------------KE 108

  Fly   191 LEEVQTDLRKREDELLRKASRKYEDAEGKRKNSNSDKEDASEQALIHGRNSISTAAGSTTDMQHR 255
            .:||      ||                            |:|:|
pombe   109 SKEV------RE----------------------------SQQSL-------------------- 119

  Fly   256 QRKQRNHLNNNNSKQNSCDKTGNDDDDRDQHESEVFLKEGGRIVEQLKLKTFPSSPAHSAASSNQ 320
                          :|..||.           .::.:.|     |.:|.......||.:.:||..
pombe   120 --------------ENEFDKV-----------EKIIVNE-----EDMKKTLELGLPASNRSSSTL 154

  Fly   321 TEQTNSIAASTATVDVQLAGHPTDPSVGGASEPRAPLAGHDSMHSLNGSLNGESGPVNGALKARL 385
            .::...:.:.:                                                ..|...
pombe   155 KDKFFKVFSMS------------------------------------------------CFKNLF 171

  Fly   386 DRDVNAALVNDAESGRRRPQKRGATYFTMRILAQAFTMTFLAEWGDRSQLTTIILAASKDVYGVI 450
            .:..:.|.:                        :||.:.|::|.|||||:.||:::|.:.|..|.
pombe   172 SKKFSRAFI------------------------KAFALIFVSELGDRSQIATIVMSAKEKVLDVF 212

  Fly   451 AGGIIGHCICTGLAVIGGRLVASKISVRTVTIVGGIVFIGFAI 493
            .|..|||.:||.:|||.||.:::||.:..|...|||||:.|.|
pombe   213 IGVNIGHMLCTMVAVIVGRYISNKIEMYKVLFFGGIVFMIFGI 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42542	NP_001163614.1	Gdt1	97..>183	CDD:225030	36/86 (42%)
		UPF0016	104..172	CDD:279508	28/68 (41%)
		Gdt1	<416..496	CDD:225030	35/78 (45%)
		UPF0016	423..492	CDD:279508	31/68 (46%)
SPAC186.05c	NP_595023.1	Gdt1	24..262	CDD:225030	91/400 (23%)
		UPF0016	33..102	CDD:279508	28/68 (41%)
		UPF0016	185..254	CDD:279508	31/68 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	1.000	Domainoid score	I2040
eggNOG	1	0.900	-	-		E1_COG2119
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1225
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002397
OrthoInspector	1	1.000	-	-		otm47283
orthoMCL	1	0.900	-	-		OOG6_101338
Panther	1	1.100	-	-	O	PTHR12608
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2098
TreeFam	1	0.960	-	-
	11	10.820