Protein Alignment Ir75b and grik5

DIOPT Version :9

• Sequence 1: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_001315085.1
• Gene: grik5 / 798791
• ZFINID: ZDB-GENE-070821-6
• Length: 1067
• Species: Danio rerio
• Alignment Length: 754
• Identity: 154/754 - (20%)
• Similarity: 272/754 - (36%)
• Gaps: 220/754 - (29%)

  Fly     1 MLQLHNLILHNLIHMAKLSHVLILHCSLSHLALLAQSKNIFTQFQPLHSDIQLNDDFLNHNILKL 65
            :|:|..||...||....|| :.:|..:|....||.                ::.||       |:
Zfish   184 LLRLEELIRRFLISRETLS-IRMLDDNLDPTPLLK----------------EIRDD-------KI 224

  Fly    66 G-VFLDINCDKSGTVLDMASAKRFFSHRYHWLIYDRSMNFSV--LESHFKEAQIFVDADVTYVTH 127
            . :.:|.|...|..:|..||.....|..|.:::  .:|:|.:  |:....|....|...:...||
Zfish   225 ATIIIDANASISYLILKKASELGMTSAFYKYIL--TTMDFPLLWLDDIVDEQSNIVGFSMFNTTH 287

  Fly   128 DPFSKNF-------------------------LLYDVYNKGRQLGGELNITADREIFCNKTNC-- 165
             ||...|                         ||:|..:.......|||  ..:||.....:|
Zfish   288 -PFYLEFIRSLNLSWREGCDINPYPGPALSSALLFDAVHVVVSAVQELN--RSQEIGVKPLSCTS 349

  Fly   166 -RVERYLSEL--YTRSALQHRKSFTGLTMRA---------------------------------T 194
             ::.::.:.|  |.|..     .:.|||.|.                                 |
Zfish   350 PQIWQHGTSLMNYLRMV-----EYDGLTGRVEFNSKGQRTNYTLHILEKHRGGHKEIGIWYSNNT 409

  Fly   195 AVVTALPLNVSIKE--------IFDFMNSKYRIQLDTYARLGYQARQ-----------PLRDMLD 240
            .::.:..|::::.|        |...:.:.|.::     ::.||..:           .||::.|
Zfish   410 LLMNSTSLDINVSETLANKSLIITTILENPYVMR-----KINYQEFEGNEQYEGFCVDMLRELSD 469

  Fly   241 CKFKYIFRDRWSDGNATG---------GMIGDLILDKADLAIAPFIYSFDRAL---FLQPITK-- 291
            . .|:.:|.:..|....|         ||:|:||..|||||:|.|..:.:|..   |.:|...
Zfish   470 I-LKFTYRIKLVDDGLYGAPEPNGSWTGMVGELINRKADLAVAAFTITSEREKVIDFSKPFMTLG 533

  Fly   292 FSVFREICMFRNPRSVSAGLSATEFLQPFSGGVWLTFALLLLLAGCLLWVTFILERRKQWKP--- 353
            .|:...:.:.|.|...|       ||.|||..|||...|..|...|:|:::..|...:.:.|
Zfish   534 ISILYRVHIGRKPGYFS-------FLDPFSPAVWLFMLLAYLAVSCVLFLSARLSPYEWYNPHPC 591

  Fly   354 ------------SLLTSCLLSFGAGCIQGAWLTPRSMGGR------MAFFALMVTSYLMYNYYTS 400
                        :|..|.....|....||:.:.||::..|      .||..::::|      ||:
Zfish   592 LRERRDLLENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISS------YTA 650

  Fly   401 IVVSKLLGQPIKSNIRTLQQLAD-SNLDVGIEPTVY---TRIYVETSEEPDVRDLYRKKVLGSKR 461
            .:.:.|..|.::..|.:...||| :|:..|   |::   |..:...|.....:.::  ..:.||:
Zfish   651 NLAAFLTVQRMEVPIESPDDLADQTNIQYG---TIHGGSTMTFFMNSRYQTYQRMW--NYMYSKQ 710

  Fly   462 SPDKIWIPTEAGVLSVRDQEGFVYITGVATGYEFVRKHFL--AHQI--CELNEI-PLRDASHTHT 521
             |......||.|:..|           |.:.|.|:.:..:  .|:.  |.|.:| .|.|......
Zfish   711 -PSVFVKSTEEGIARV-----------VNSKYAFLLESTMNEYHRSLNCNLTQIGGLLDTKGYGI 763

  Fly   522 VLAKRSPYAELIKLSELRMLETG-VHFKHERSWMETKLHCYQHNHTVAVGLEYAAPLFIILLGAI 585
            .:...||:.:.:.|:.|::.|.. :.....|.|...|....:.:....:|:|....:|::|:..:
Zfish   764 GMPLGSPFRDELSLAVLQLQENNRLEILKRRWWEGGKCPKEEDHRAKGLGMENIGGIFVVLICGL 828

  Fly   586 ILCMGILGLEVIW--------------------HRHCTL 604
            |:.:.:..:|.:|                    |.|.|:
Zfish   829 IIAVFVAVMEFVWSTRRSAETDEVRPLSCDRQYHSHTTV 867

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75b	NP_001137966.2	Periplasmic_Binding_Protein_Type_2	253..553	CDD:304360	81/344 (24%)
		Lig_chan	343..585	CDD:278489	54/272 (20%)
grik5	NP_001315085.1	PBP1_iGluR_Kainate_KA1_2	38..412	CDD:107389	50/261 (19%)
		ANF_receptor	55..392	CDD:279440	49/241 (20%)
		Periplasmic_Binding_Protein_Type_1	<313..383	CDD:299141	16/76 (21%)
		Periplasmic_Binding_Protein_Type_2	427..797	CDD:304360	90/405 (22%)
		Lig_chan	558..828	CDD:278489	61/292 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591258
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840