Protein Alignment Ir75b and grik1b

DIOPT Version :10

• Sequence 1: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_690040.5
• Gene: grik1b / 561540
• ZFINID: ZDB-GENE-070821-1
• Length: 906
• Species: Danio rerio
• Alignment Length: 592
• Identity: 118/592 - (19%)
• Similarity: 211/592 - (35%)
• Gaps: 147/592 - (24%)

  Fly    91 HRYH-WLIYDRSMNFSVLESHFKEA-------QIFV----------DADVTYVTHD--------- 128
            ||:. |....|.:      |.||||       ||.:          |.|:..:..|
Zfish   376 HRHKPWRFGSRFI------SMFKEAQWNGLTGQIIINKTDGLRKDFDLDIISLKEDGLEKPLESG 434

  Fly   129 PFSKNFLLYDVYNKGRQLGGELNIT-ADREIFCNKTNCRVERYL--SELYTRSALQHRKS----- 185
            .|:|.:....|:|...    .||:| ::::...|.|:....|.|  :.:.....:.::||
Zfish   435 RFNKVWKKIGVWNSNT----GLNLTDSNKDKNTNVTDSMANRTLIVTTILENPYVMYKKSDKPLY 495

  Fly   186 ----FTGLTMRATAVVTALPLNVSIKEIFDFMNSKYRIQLDTYARLGYQARQPLRDMLDCKFKYI 246
                |.|..:..            :||:.:.:...|.::|.|..:.|.|
Zfish   496 GNDRFEGYCLDL------------LKELSNILGFSYEVKLVTDGKYGAQ---------------- 532

  Fly   247 FRDRWSDGNATGGMIGDLILDKADLAIAPFIYSFDRALFLQPITKFSVFREICMFRNPRSVSAGL 311
                 :|.....||:.:||...||||:||...::.|...:.....|.......::..|...:.|:
Zfish   533 -----NDKGEWNGMVRELIDHVADLAVAPLTITYVREKVIDFSKPFMTLGISILYHKPNGTNPGV 592

  Fly   312 SATEFLQPFSGGVWLTFALLLLLAGCLLWVTFILERRKQWKP--------------SLLTSCLLS 362
            .:  ||.|.|..:|:...|..|...|:|:|.......:.:.|              :|:.|....
Zfish   593 FS--FLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLINSVWFG 655

  Fly   363 FGAGCIQGAWLTPRSM-----GGRMAFFALMVTSYLMYNYYTSIVVSKLLGQPIKSNIRTLQQLA 422
            .||...||:.|.|:::     ||...||.|::.|....|....:.|.::
Zfish   656 VGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERM---------------- 704

  Fly   423 DSNLDVGIEPTVYTRIYVETSEEPDVRDLYRKKVLGSKRSPDKIWI---PTEAGVLSVRDQEGF- 483
            ||.:|...:....|:|......:......::|..:.:.   :|:|.   ..:...|...::||.
Zfish   705 DSPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTY---EKMWAFMSSRKNTALVKNNREGIQ 766

  Fly   484 -VYITGVATGYEFVRKHFLAHQICELNEI-PLRDASHTHTVLAKRSPYAELIKLSELRMLETG-V 545
             |..|..|...|.....:::.:.|.|.:| .|.|:..........|||.:.:.::.|::.|.| :
Zfish   767 RVLTTDYALLMESTSIEYISQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKVTIAILQLQEEGKL 831

  Fly   546 HFKHERSWMETKLHCYQHNHTVAVGLEYAAPLFIILLGAIILCMGI------------LGLEVI- 597
            |...|:.|..............|:|:|....:||:|...::|.:.:            |.:|.:
Zfish   832 HMMKEKWWRGNGCPEEDSKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNLDIEEVS 896

  Fly   598 -----WH 599
                 ||
Zfish   897 VGQCEWH 903

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75b	NP_001137966.2	Lig_chan-Glu_bd	<235..283	CDD:463166	11/47 (23%)
		Periplasmic_Binding_Protein_Type_2	<259..>325	CDD:473866	18/65 (28%)
		Lig_chan	343..584	CDD:459656	52/266 (20%)
grik1b	XP_690040.5	PBP1_iGluR_Kainate	65..456	CDD:380605	20/89 (22%)
		Periplasmic_Binding_Protein_Type_2	471..840	CDD:473866	83/422 (20%)