Protein Alignment Ir75b and grid1b

DIOPT Version :10

• Sequence 1: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_009304811.1
• Gene: grid1b / 557511
• ZFINID: ZDB-GENE-121214-84
• Length: 1048
• Species: Danio rerio
• Alignment Length: 692
• Identity: 138/692 - (19%)
• Similarity: 241/692 - (34%)
• Gaps: 168/692 - (24%)

  Fly     4 LHNLILHNLIHMAKLSHVLILHCSLSHLAL--LAQSK----NIFTQFQPLHSDIQLNDDFLNHNI 62
            :|..:..||  .:|.||.:.::..:|...:  ||.|.    .:..|..||..|..::....:|.|
Zfish   240 IHQAVETNL--ASKDSHWVFVNEEISDTEILELAHSSLGRMTVVRQIFPLWRDSSVSCMRNSHRI 302

  Fly    63 LKLGVFLDINCDKSGTVLDMASAKRFFSHRYHWLIYDRSMNFSVLESHF------KEAQIFVDAD 121
            ..|      .||.....|........:       :||..:   :|.:.|      ::.......:
Zfish   303 SSL------LCDPQEGYLQSLEVSNLY-------LYDSVL---MLANAFYRKLEDRKWHSMASLN 351

  Fly   122 VTYVTHDPFSKNFLLYDVYNKGRQLGGELNITADREIFCNKTNCRVE-------------RYLSE 173
            ....:..|::..:.:.:...|||..|    :|...:...|.:|..|:             :.:..
Zfish   352 CIRKSTKPWNGGWSMLETIQKGRITG----LTGIMDFMENGSNSHVQFEILGTSFSETFGKDIKR 412

  Fly   174 LYT-------RSALQHRKSFTGLTMRATAVVTALPLNVSIKEIFDFMNSKYRIQLDTYARLGYQA 231
            |.|       ..:|:..:...|:......|||.|      ::.|..:......|...|.......
Zfish   413 LATWDSVHGLNGSLKESRIENGMQGVTVKVVTLL------EDPFVMVAENILGQPKRYKGFSIDV 471

  Fly   232 RQPLRDMLDCKFKY-IFR-------DRWSDGNATGGMIGDLILDKADLAIAPFIYSFDRALFLQP 288
            .:.|..:|.  ||| |::       .:.|:| :..||||:||..:||||::....:.:|...:..
Zfish   472 LEALAKILG--FKYDIYQVADSKYGSQLSNG-SWNGMIGELINKRADLAVSAITITPERENVVDF 533

  Fly   289 ITKFSVFREICMFRNPRSVSAGLSATEFLQPFSGGVWLTFALLLLLAGCLLWVTFILER----RK 349
            ..::..:....:.|.|..   .::......||...||...|..:.:.|.|:   |:|.|    |.
Zfish   534 SKRYMDYSVGILHRKPEE---KINIFSLFAPFDLAVWACIAAAIPVVGVLI---FLLTRMQMLRS 592

  Fly   350 QWKP----------SLLTSCLLSFGAGCIQG-----AWLTPRSMGGRMAFFALMVTSYLMYNYYT 399
            |..|          ||.::..:.:||...||     ..:..|.:.|....|.|:|.|....|...
Zfish   593 QNPPGAHHASSMSNSLHSAIWIVYGAFVQQGGDSVVGSVALRIVMGSWWLFTLIVCSSYTANLAA 657

  Fly   400 SIVVSKLLGQPIKSNIRTLQQLA-----------DSNL-----DVGIEPTVYTRIYVE---TSEE 445
            .:.||::     .:.|||.|.||           ||.:     ..|..|......|.|   |..:
Zfish   658 FLTVSRM-----DNTIRTFQDLARQMDFAYGTVRDSAVYDYFKAKGTNPLEQDSTYAELWRTISK 717

  Fly   446 PDVRDL--------YRKKVLGSKRSPDK-IWIPTEAGVLSVRDQEGFVYITG---VATGYEFVRK 498
            .:.:|.        .||    :|:.|.. :|........::.|.:..:.::|   .:.||....:
Zfish   718 NNGQDFSVSSPSEGIRK----AKKGPYAFLWDMAVVEYAALTDDDCTITVSGNSMSSKGYGIAMQ 778

  Fly   499 HFLAHQICELNEIPLRDASHTHTVLAKRSPYAELIKLSELRMLETGVHFKHERSWMETKLHCYQH 563
            |                          .|||.:||....|.:.|.|.....::.|......|..:
Zfish   779 H--------------------------GSPYRDLISQKILELQEKGDLDVLKQKWWPRTGRCDLN 817

  Fly   564 NHTVA------VGLEYAAPLFIILLGAIILCMGILGLEVIWH 599
            :|:.|      :.|...|.:|.||...::|...:..||:.|:
Zfish   818 SHSNAQPDGRSLKLHSFAGVFCILAAGLLLACLVAALEMWWN 859

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75b	NP_001137966.2	Lig_chan-Glu_bd	<235..283	CDD:463166	18/55 (33%)
		Periplasmic_Binding_Protein_Type_2	<259..>325	CDD:473866	15/65 (23%)
		Lig_chan	343..584	CDD:459656	62/296 (21%)
grid1b	XP_009304811.1	PBP1_iGluR_delta_1	25..426	CDD:380615	35/207 (17%)
		Periplasmic_Binding_Protein_Type_2	437..809	CDD:473866	89/421 (21%)