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Protein Alignment Ir75b and Gria3

DIOPT Version :9

Sequence 1:	NP_001137966.2	Gene:	Ir75b / 8673994	FlyBaseID:	FBgn0261402	Length:	605	Species:	Drosophila melanogaster
Sequence 2:	NP_001268858.2	Gene:	Gria3 / 53623	MGIID:	95810	Length:	888	Species:	Mus musculus

Alignment Length:	565	Identity:	121/565 - (21%)
Similarity:	207/565 - (36%)	Gaps:	180/565 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 HWLIYDRSMNFSVLESHFKEAQIFVDAD--------VTYVTHDPFSKNFLLYDVYNKG-RQLGGE 149
            :|..|:|.:.||       :.||..|:.        ||.:...|       |.:|.|. .||.|
Mouse   392 YWNEYERFVPFS-------DQQISNDSSSSENRTIVVTTILESP-------YVMYKKNHEQLEG- 441

  Fly   150 LNITADREIFCNKTNCRVERYLSELYTRSALQHRKSFTGLTMRATAVVTALPLNVSIKEIFDFMN 214
                          |.|.|.|..:|                               ..||...:.
Mouse   442 --------------NERYEGYCVDL-------------------------------AYEIAKHVR 461

  Fly   215 SKYRIQLDTYARLG---YQARQPLRDMLDCKFKYIFRDRWSDGNATGGMIGDLILDKADLAIAPF 276
            .||::.:     :|   |.||.|     :.|.       |:      ||:|:|:..:||:|:||.
Mouse   462 IKYKLSI-----VGDGKYGARDP-----ETKI-------WN------GMVGELVYGRADIAVAPL 503

  Fly   277 IYSFDRAL---FLQPITKFSVFREICMFRNPRSVSAGLSATEFLQPFSGGVWLTFALLLLLAGCL 338
            ..:..|..   |.:|.....:   ..|.:.|:....|:.:  ||.|.:..:|:          |:
Mouse   504 TITLVREEVIDFSKPFMSLGI---SIMIKKPQKSKPGVFS--FLDPLAYEIWM----------CI 553

  Fly   339 LW-------VTFILERRK--QW-------KP-------------SLLTSCLLSFGAGCIQGAWLT 374
            ::       |.|::.|..  :|       :|             .:..|...|.||...||..::
Mouse   554 VFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDIS 618

  Fly   375 PRSMGGRMA-----FFALMVTSYLMYNYYTSIVVSKLLGQPIKS--NIRTLQQLADSNLDVGIEP 432
            |||:.||:.     ||.|::.|....|....:.|.::: .||:|  ::....::|...||.|...
Mouse   619 PRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV-SPIESAEDLAKQTEIAYGTLDSGSTK 682

  Fly   433 TVYTRIYVETSEEPDVRDLYRKKVLGSKRSPDKIWIPTEA-GVLSVRDQEG-FVYITGVATGYEF 495
            ..:.|..:.         :|.|.....|.:...::..|.| ||..||..:| |.::. .:|..|:
Mouse   683 EFFRRSKIA---------VYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLL-ESTMNEY 737

  Fly   496 VRKHFLAHQICELNEIPLRDASHTHTVL-----AKRSPYAELIKLSELRMLETGVHFKHERSWME 555
            :.:    .:.|:..::.....|..:.|.     |.|:|    :.|:.|::.|.|:..|.:..|..
Mouse   738 IEQ----RKPCDTMKVGGNLDSKGYGVATPKGSALRTP----VNLAVLKLSEQGILDKLKNKWWY 794

  Fly   556 TKLHC-----YQHNHTVAVGLEYAAPLFIILLGAIILCMGILGLE 595
            .|..|     ...:.|.|:.|...|.:|.||:|.:.|.|.:..:|
Mouse   795 DKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIE 839

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.