Protein Alignment Ir75b and gria3b

DIOPT Version :9

• Sequence 1: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_938174.1
• Gene: gria3b / 368416
• ZFINID: ZDB-GENE-030616-53
• Length: 883
• Species: Danio rerio
• Alignment Length: 814
• Identity: 149/814 - (18%)
• Similarity: 265/814 - (32%)
• Gaps: 312/814 - (38%)

  Fly    17 KLSHVLILHCSLSHLALLAQSKNIFTQFQPLHSDIQLNDDFLNHNILKLGVFLDINCDKSGTVLD 81
            |..:.|...|...|.:.:..|       .|:.||:|.              .:.:.....|.||.
Zfish    98 KSMNTLTSFCGALHTSFVTPS-------YPIDSDVQF--------------VIQMRPPLKGAVLS 141

  Fly    82 MASAKRFFSHRYHW----LIYDRSMNFSVLES------------------------HFK------ 112
            :.|       .|.|    .:||....||:|::                        .|:
Zfish   142 LLS-------HYKWDKFVYLYDTDRGFSILQAIMEAAVANNWQVTARSVGSITDPQEFRRIIEEM 199

  Fly   113 ----EAQIFVDADVTYVTHDPFSKNFLLYDVYNKGRQLGGE---------LNITADREIF----- 159
                |.:..:|.:|..:       |.:|..|...|:...|.         .||:.|: :|
Zfish   200 DRRQEKRYLIDCEVDRI-------NVILEQVVTLGKNSRGYHYIIANLGFTNISLDK-VFLGGAN 256

  Fly   160 ------CNKTNCRVERYLSE-----------------LYTRSALQH-------------RKSFTG 188
                  .|..|..|:::|..                 .|| |||.:             |:....
Zfish   257 ISGFQIINPENLVVQQFLQRWDRLDEREFPEAKNTPLKYT-SALSYDAILVIAEAFRYLRRQRVD 320

  Fly   189 LTMRATA----VVTALP------LNVSIKEI----------FDFMNSKYRIQLDTY-------AR 226
            ::.|.:|    ...|:|      :..::|.:          ||....:....:|.|       .:
Zfish   321 VSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDSFGRRTNYTIDVYEMKTGGPRK 385

  Fly   227 LGY-QARQPLRDMLDCKF----------------------------------------------- 243
            :|| ...:...:::|.:|
Zfish   386 IGYWNEFERFVNIMDQQFTNDSSSVENRTIVVTTIMEAPYVMYKKNHMHLEGNEKYEGYCVDLAS 450

  Fly   244 ------------------KYIFRDRWSDGNATGGMIGDLILDKADLAIAPFIYSFDRAL---FLQ 287
                              ||..||  .:..:..||:|:|:..:||:|:||...:..|..   |.:
Zfish   451 EIAKHVGIKYRLSIVMDGKYGARD--PETKSWNGMVGELVYGRADIAVAPLTITLVREEVIDFSK 513

  Fly   288 PITKFSVFREICMFRNPRSVSAGLSATEFLQPFSGGVWLTFALLLLLAGCLLW-------VTFIL 345
            |.....:   ..|.:.|:....|:.:  ||.|.:..:|:          |:::       |.|::
Zfish   514 PFMSLGI---SIMIKKPQKSKPGVFS--FLDPLAYEIWM----------CIVFAYIGVSVVLFLV 563

  Fly   346 ERRK--QWK----------------PS---LLTSCLLSFGAGCIQGAWLTPRSMGGRMA-----F 384
            .|..  :|:                |:   :..|...|.||...||..::|||:.||:.     |
Zfish   564 SRFSPYEWQLDETDEVKDPQTPPDPPNDFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWF 628

  Fly   385 FALMVTSYLMYNYYTSIVVSKLLGQPIKS--NIRTLQQLADSNLDVGIEPTVYTR----IYVE-- 441
            |.|::.|....|....:.|.::: .||:|  ::....::|...||.|.....:.|    :|.:
Zfish   629 FTLIIISSYTANLAAFLTVERMV-SPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMW 692

  Fly   442 ---TSEEPDVRDLYRKKVLGSKRSPDKIWIPTEAGVLSVRDQEG-FVYITGVATGYEFVRKHFLA 502
               .|.||.|         .:|.:||        ||..||..:| |.::. .:|..|::.:
Zfish   693 SYMKSAEPSV---------FAKTTPD--------GVARVRKSKGKFAFLL-ESTMNEYIEQ---- 735

  Fly   503 HQICELNEIPLR-DASHTHTVLAKRSPYAELIKLSELRMLETGVHFKHERSWMETKLHC-----Y 561
            .:.|:..::... |:........|.|.....:.|:.|::.|.|:..|.:..|...|..|     .
Zfish   736 RKPCDTMKVGGNLDSKGYGVATPKGSALRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGD 800

  Fly   562 QHNHTVAVGLEYAAPLFIILLGAIILCMGILGLE 595
            ..:.|.|:.|...|.:|.||:|.:.|.|.:..:|
Zfish   801 SKDKTSALSLSNVAGVFYILVGGLGLAMMVALIE 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75b	NP_001137966.2	Periplasmic_Binding_Protein_Type_2	253..553	CDD:304360	75/348 (22%)
		Lig_chan	343..585	CDD:278489	65/285 (23%)
gria3b	NP_938174.1	Periplasmic_Binding_Protein_Type_1	25..396	CDD:299141	54/334 (16%)
		ANF_receptor	36..379	CDD:279440	52/317 (16%)
		PBP2_iGluR_AMPA	412..794	CDD:270433	81/421 (19%)
		Lig_chan	544..824	CDD:278489	68/312 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591264
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740