Protein Alignment Ir75b and Ir31a

DIOPT Version :10

• Sequence 1: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_061519115.1
• Gene: Ir31a / 3291880
• VectorBaseID: AGAMI1_005634
• Length: 763
• Species: Anopheles gambiae
• Alignment Length: 529
• Identity: 125/529 - (23%)
• Similarity: 216/529 - (40%)
• Gaps: 62/529 - (11%)

  Fly    95 WLIYDRSMNFSVL-ESHFKEAQIFVDADVTYVTHDPFSKN-FLLYDVYNKGRQLGGELNITADRE 157
            ||:..|:....:| ...:..|.|.:::|:.........:. |.|:|:|:|||.|        .::
Mosquito     7 WLLLSRNTTADLLPRVLWNTAGIQMNSDLVAAIETTDHRGVFNLFDIYSKGRHL--------CKD 63

  Fly   158 IF---CNKTNCRVERYLSELYTRSALQHRKSFTGLTMRATAVVTALPLNVSIKEIFDFMNSKYRI 219
            ||   ....:..|...|:..|  |..:.|::|..|.:|...|:..  .||:..::...:......
Mosquito    64 IFQTLLGTWSADVGFRLTPNY--SPYKIRQNFNFLQLRGVTVIDR--ENVTSGKVDQLLGEPGLT 124

  Fly   220 Q-LDTYARLGYQARQPLRDMLDCKFKYIFRDRWSDGNATG---GMIGDLILDKADLAIAPFIYSF 280
            : :..:.:..|.....|||..:...|:.....|:....:|   |::|.:...:.|:|....|...
Mosquito   125 KGIVAFVKYHYALLVVLRDFHNFTIKFRPTRGWAGRLRSGYRLGLLGVVQRHETDVAATGIIMRL 189

  Fly   281 DRALFLQPITKFSVFREICMFRNPRSVSAGLSATEFLQPFSGGVWLTFALLLLLAGCLLWVTFIL 345
            .|...|..|.....|....:::....:.:......|:.|||..||:  ||||.||..:|.:.::.
Mosquito   190 SRQPELDSIHYSWAFETGFIYKITPDIGSKSEGNGFVAPFSLPVWV--ALLLSLALSVLVLQYLA 252

  Fly   346 ERRKQWKPSLLTSCLLSFGAGCI--QGAWLTPRSMGGRMAFFALMVTSYLMYNYYTSIVVSKLLG 408
            ......:.:..|...:.....|:  ||.....|.:..|:|...|:|.:.::||||||.|||.||.
Mosquito   253 RLSADERNTRATMAYVLDVMACVAQQGVPNVSRLVPTRVAVIVLLVANLVLYNYYTSTVVSGLLS 317

  Fly   409 QPIKSNIRTLQQLADSNLDVGIEPTVYTRIYVETSEEPDVRDLYRKKVLGSKRSPD--KIWIPTE 471
            ..: ....|:.|:.||.|.:.:..|.|.||.:.....|....::.:|.| ..|||:  .::...|
Mosquito   318 SQM-IGPETIAQVIDSPLLLSLTDTGYHRILLREQTLPYSTRMHERKAL-PPRSPNDLPLFTDVE 380

  Fly   472 AGVLSVRDQEGFVYITGVATGYEFVRKHFLAHQICELNEIP---LRDASHTHTVLAKRSPYAELI 533
            ..|..:| :.|.|....:...|..:...|.|::||||..:.   ..|......||.|.|.|:||.
Mosquito   381 HAVPYLR-RGGHVLHCELTEVYPAIANQFTANEICELRTVEGLYRYDIRVMAFVLPKHSMYSELF 444

  Fly   534 KLSELRMLETGVHFK---------HERSWME--TKLHCYQHNHTVAVGLEYAAPLFIILLGAIIL 587
            |::      .|..|:         .|.|::.  |....|.           .|.:..::|| ::.
Mosquito   445 KIT------LGFIFRLTPELNGATRETSYLSPFTDTTWYS-----------VASVLALVLG-VLQ 491

  Fly   588 CMGILGLEV 596
            |:.|...|:
Mosquito   492 CIAIFHAEL 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75b	NP_001137966.2	Lig_chan-Glu_bd	<235..283	CDD:463166	11/50 (22%)
		Periplasmic_Binding_Protein_Type_2	<259..>325	CDD:473866	13/65 (20%)
		Lig_chan	343..584	CDD:459656	64/258 (25%)
Ir31a	XP_061519115.1	None