Protein Alignment Ir75b and Gria4

DIOPT Version :9

• Sequence 1: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_001106655.1
• Gene: Gria4 / 29629
• RGDID: 61863
• Length: 902
• Species: Rattus norvegicus
• Alignment Length: 523
• Identity: 118/523 - (22%)
• Similarity: 203/523 - (38%)
• Gaps: 114/523 - (21%)

  Fly   137 YDVYNKGRQLGGELNITADREIF-CNKTNCRVERYLSELYTRSALQHRKSF---TGLTMRATAVV 197
            :|.|      |..:|.|.|  :| ...|..|...|.:::.....:|...:.   |......|.||
  Rat   363 FDHY------GRRVNYTMD--VFELKSTGPRKVGYWNDMDKLVLIQDMPTLGNDTAAIENRTVVV 419

  Fly   198 TAL---PLNVSIK--EIFDFMNSKYRIQLDTYARLGY--QARQPLRDMLDCKF--------KYIF 247
            |.:   |..:..|  |:|: .|.||.         ||  .....:...:..|:        ||..
  Rat   420 TTIMESPYVMYKKNHEMFE-GNDKYE---------GYCVDLASEIAKHIGIKYKIAIVPDGKYGA 474

  Fly   248 RDRWSDGNATGGMIGDLILDKADLAIAPFIYSFDRAL---FLQPITKFSVFREICMFRNPRSVSA 309
            ||  :|.....||:|:|:..||::||||...:..|..   |.:|.....:   ..|.:.|:....
  Rat   475 RD--ADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGI---SIMIKKPQKSKP 534

  Fly   310 GLSATEFLQPFSGGVWLTFALLLLLAGCLLW-------VTFILERRK--QWK----------PS- 354
            |:.:  ||.|.:..:|:          |:::       |.|::.|..  :|.          ||
  Rat   535 GVFS--FLDPLAYEIWM----------CIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSD 587

  Fly   355 -------LLTSCLLSFGAGCIQGAWLTPRSMGGRMA-----FFALMVTSYLMYNYYTSIVVSKLL 407
                   :..|...|.||...||..::|||:.||:.     ||.|::.|....|....:.|.:::
  Rat   588 QPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV 652

  Fly   408 GQPIKS--NIRTLQQLADSNLDVGIEPTVYTRIYVETSEEPDVRDLYRKKVLGSKRSPDKIWIPT 470
             .||:|  ::....::|...||.|.....:.|..:.         :|.|.....:.:...::..|
  Rat   653 -SPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIA---------VYEKMWTYMRSAEPSVFTRT 707

  Fly   471 EA-GVLSVRDQEG-FVYITGVATGYEFVRKHFLAHQICELNEIPLR-DASHTHTVLAKRSPYAEL 532
            .| ||..||..:| |.::. .:|..|::.:    .:.|:..::... |:........|.|.....
  Rat   708 TAEGVARVRKSKGKFAFLL-ESTMNEYIEQ----RKPCDTMKVGGNLDSKGYGVATPKGSSLRNA 767

  Fly   533 IKLSELRMLETGVHFKHERSWMETKLHC-----YQHNHTVAVGLEYAAPLFIILLGAIILCMGIL 592
            :.|:.|::.|.|:..|.:..|...|..|     ...:.|.|:.|...|.:|.||:|.:.|.|.:.
  Rat   768 VNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVA 832

  Fly   593 GLE 595
            .:|
  Rat   833 LIE 835

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75b	NP_001137966.2	Periplasmic_Binding_Protein_Type_2	253..553	CDD:304360	74/339 (22%)
		Lig_chan	343..585	CDD:278489	62/276 (22%)
Gria4	NP_001106655.1	PBP1_iGluR_AMPA_GluR4	28..398	CDD:107383	10/42 (24%)
		ANF_receptor	39..380	CDD:279440	7/24 (29%)
		PBP2_iGluR_AMPA_GluR4	414..795	CDD:270445	94/422 (22%)
		Lig_chan	546..825	CDD:278489	65/303 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349830
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740