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Protein Alignment Ir75b and GRIN2D

DIOPT Version :9

Sequence 1:	NP_001137966.2	Gene:	Ir75b / 8673994	FlyBaseID:	FBgn0261402	Length:	605	Species:	Drosophila melanogaster
Sequence 2:	NP_000827.2	Gene:	GRIN2D / 2906	HGNCID:	4588	Length:	1336	Species:	Homo sapiens

Alignment Length:	402	Identity:	93/402 - (23%)
Similarity:	155/402 - (38%)	Gaps:	106/402 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   259 GMIGDLILDKADLAIAPFIYSFDRALFLQPITKFSV-FRE----ICMFRNPRSVSAGLSATEFLQ 318
            ||||::...:||:||.....:.:|:    .|..||| |.|    :.:.|:..:|    |.:.||:
Human   523 GMIGEVFYQRADMAIGSLTINEERS----EIVDFSVPFVETGISVMVARSNGTV----SPSAFLE 579

  Fly   319 PFSGGVWLTFALLLLLAGCLLWV---TFILERRKQ--WKPSLLTSCL---LSFGAGCIQGAWL-- 373
            |:|..||     :::...||..|   .||.|....  :..||.|...   .:|..|  :..||
Human   580 PYSPAVW-----VMMFVMCLTVVAVTVFIFEYLSPVGYNRSLATGKRPGGSTFTIG--KSIWLLW 637

  Fly   374 -----------TPRSMGGRM-----AFFALMVTSYLMYNYYTSIVVSKLLGQPIKSNIRTLQQLA 422
                       .||....::     ||||::..:     .||:.:.:.::.:   ..:.|:..|:
Human   638 ALVFNNSVPVENPRGTTSKIMVLVWAFFAVIFLA-----SYTANLAAFMIQE---EYVDTVSGLS 694

  Fly   423 DSN----------LDVGIEPTVYTRIYVETSEEPDVR----DLYRKKVLGSKRSPDKIWIPTEAG 473
            |..          |..|..|        ..|.|.::|    |::...|..::...::.....:||
Human   695 DRKFQRPQEQYPPLKFGTVP--------NGSTEKNIRSNYPDMHSYMVRYNQPRVEEALTQLKAG 751

  Fly   474 VLSVRDQEGFVYITGVATGYEFVRKHFLAH--QICELNEIPLRDASHT---HTVLAKRSPYAELI 533
            .|     :.|:|...|.        :::|.  :.|:|..|.......|   ...|.|.|.:...|
Human   752 KL-----DAFIYDAAVL--------NYMARKDEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPI 803

  Fly   534 KLSELRMLETGVHFKHERSWMETKLHCYQHNHTVAV-----GLEYAAPLFIILLGAIILCMGILG 593
            .|:.|:.|........||.|:..  .|  ||..:.|     .::..|.:|.:||.|:.|.:.:..
Human   804 DLALLQFLGDDEIEMLERLWLSG--IC--HNDKIEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFA 864

  Fly   594 LE--VIWH-RHC 602
            .|  |.|. |||
Human   865 WEHLVYWRLRHC 876

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.