Protein Alignment Ir75b and Grin2c

DIOPT Version :9

• Sequence 1: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_036707.3
• Gene: Grin2c / 24411
• RGDID: 2739
• Length: 1250
• Species: Rattus norvegicus
• Alignment Length: 563
• Identity: 116/563 - (20%)
• Similarity: 204/563 - (36%)
• Gaps: 149/563 - (26%)

  Fly    94 HWLIYDRSMNFSVLESHFKEAQIFVDA-DVTYVTHDPFSKNFLLYDVYNKGRQLGGELNITADRE 157
            |.::|   |.:.|...:....|..||: .:|..|.:  .:.|::.:..:.|  .||
  Rat   390 HGVLY---MKYPVWPRYSTSLQPVVDSRHLTVATLE--ERPFVIVESPDPG--TGG--------- 438

  Fly   158 IFC--NKTNCRVERYLSELYTRSALQHRKSFTGLTMRATAVVTALPLNVSIKEIFDFMNSKYRIQ 220
              |  |...||.:.           .|..|...||...........::: :|::...:...|.:.
  Rat   439 --CVPNTVPCRRQS-----------NHTFSSGDLTPYTKLCCKGFCIDI-LKKLAKVVKFSYDLY 489

  Fly   221 LDTYARLGYQARQPLRDMLDCKFKYIFRDRWSDGNATGGMIGDLILDKADLAIAPFIYSFDRALF 285
            |.|..:.|.:.                |..|:      ||||::...:||:||.....:.:|:
  Rat   490 LVTNGKHGKRV----------------RGVWN------GMIGEVYYKRADMAIGSLTINEERS-- 530

  Fly   286 LQPITKFSV-FRE----ICMFRNPRSVSAGLSATEFLQPFSGGVWLTFALLLLLAGCLLWVTFIL 345
              .|..||| |.|    :.:.|:..:|    |.:.||:|:|..||     :::...||..|...:
  Rat   531 --EIIDFSVPFVETGISVMVSRSNGTV----SPSAFLEPYSPAVW-----VMMFVMCLTVVAITV 584

  Fly   346 ERRKQWKPSLLTSCLL--------SFGAGCIQGAWL-------------TPRSMGGRM-----AF 384
            ...:.:.|......|.        ||..|  :..||             .||....::     ||
  Rat   585 FMFEYFSPVSYNQNLTKGKKPGGPSFTIG--KSVWLLWALVFNNSVPIENPRGTTSKIMVLVWAF 647

  Fly   385 FALMVTSYLMYNYYTSIVVSKLLGQPIKSNIRTLQQLADSNLD----------VGIEPTVYTRIY 439
            ||::..:     .||:.:.:.::.:   ..|.|:..|:|....          .|..|...|
  Rat   648 FAVIFLA-----SYTANLAAFMIQE---QYIDTVSGLSDKKFQRPQDQYPPFRFGTVPNGST--- 701

  Fly   440 VETSEEPDVRDLYRKKVLGSKRSPDKIWIPTEAGVLSVRDQEGFVYITGVATGYEFVRKHFLA-- 502
             |.:...:.||::...|..::||.:......:.|.|     :.|:|...|.        :::|
  Rat   702 -ERNIRSNYRDMHTHMVKFNQRSVEDALTSLKMGKL-----DAFIYDAAVL--------NYMAGK 752

  Fly   503 HQICELNEIPLRDASHT---HTVLAKRSPYAELIKLSELRMLETGVHFKHERSWMETKLHCYQHN 564
            .:.|:|..|.......|   ...:.|.|.:...|.|:.|::|..|...|.|..|:..  .|....
  Rat   753 DEGCKLVTIGSGKVFATTGYGIAMQKDSHWKRAIDLALLQLLGDGETQKLETVWLSG--ICQNEK 815

  Fly   565 HTV---AVGLEYAAPLFIILLGAIILCMGILGLE--VIWH-RH 601
            :.|   .:.::..|.:|.:||.|:.|.:.:...|  |.|. ||
  Rat   816 NEVMSSKLDIDNMAGVFYMLLVAMGLALLVFAWEHLVYWKLRH 858

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75b	NP_001137966.2	Periplasmic_Binding_Protein_Type_2	253..553	CDD:304360	74/345 (21%)
		Lig_chan	343..585	CDD:278489	54/285 (19%)
Grin2c	NP_036707.3	PBP1_iGluR_NMDA_NR2	41..397	CDD:380601	3/9 (33%)
		PBP2_iGluR_NMDA_Nr2	413..813	CDD:270436	97/490 (20%)
		NMDAR2_C	850..>925	CDD:402274	4/9 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349839
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830