Protein Alignment Ir75b and glr-5

DIOPT Version :9

• Sequence 1: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_505244.1
• Gene: glr-5 / 179251
• WormBaseID: WBGene00001616
• Length: 932
• Species: Caenorhabditis elegans
• Alignment Length: 740
• Identity: 139/740 - (18%)
• Similarity: 249/740 - (33%)
• Gaps: 238/740 - (32%)

  Fly    26 CSLSHLALLAQSKNIFTQFQPLH------SDIQLNDDFLNHNILKLGVFLDINCDKSGTVLDMA- 83
            |.|.|....::...:.....|.|      :.:|:....|.|      .||..|.:.|  .:||.
 Worm   203 CRLLHKKDCSEFSRLLVDMNPEHTYTFLLASLQMGLIELKH------WFLLTNMELS--TMDMEL 259

  Fly    84 ---SAKRF-------------------FSH-RYH----WLI-YDRSMNFSVLESHFKEAQIFVDA 120
               :..||                   ||| :.|    |.: .|.|.|..::|:.|....::..|
 Worm   260 FRYNHARFISPYPVDSTFLTENRDAFNFSHFKEHITEKWAMKTDNSRNLKMMEAVFTFDAVYAFA 324

  Fly   121 DVTYVTHDPFSKNFLLYDV--------------YNKGRQ------------LGGELNITADREIF 159
            :|    .:..|.:..:.||              |..||.            |.|:|
 Worm   325 NV----FNELSSHMQMNDVPQTLCRKSSRNSRKYQHGRSLIDNIVHNDLHGLSGDL--------- 376

  Fly   160 CNKTNCRVERYLSELYTRSALQHRKSFTGLTMRATAV-----VTALPLNVS---------IKEIF 210
                     |.|:....:|....|....|.:.|...:     .|.:.:|:|         ..::.
 Worm   377 ---------RRLNGHPLKSNFSMRIQLLGYSGRLDDIGFWEPATNVHVNMSGDSKAQLQRNVQVS 432

  Fly   211 DFMNSKYRI----------------QLDTYARL-GYQARQPLRDML-----DCKFKYIF------ 247
            |.:...:|:                :||..::. |:     ..|:|     |..|.|..
 Worm   433 DELKPHFRVTTIMERPYVMLKKNHYELDANSKFEGF-----CIDLLAELSKDLGFTYTIHAVKDG 492

  Fly   248 ---RDRWSDGNATGGMIGDLILDKADLAIAPFIYSFDRAL---FLQPITKFSVFREICMFRNPRS 306
               .|::.:| :..||:|:::..:|::|:||...::.|:.   |.:|.....:   ..:::.|..
 Worm   493 KYGNDKYGNG-SWDGMMGEILRGEAEMAVAPLTVNYRRSEAVDFTKPFLSLGI---SILYKVPDD 553

  Fly   307 VSAGLSATEFLQPFSGGVWLTFALLLLLAGCLLWVTFILE-RRKQWKPSLLTSC----------- 359
            ....|.:  ||.|.|..:|...|..::..  .|.:.|:.. ...:|  :|..||
 Worm   554 QQPDLFS--FLNPLSWQIWTAIATSIITV--TLGMYFVANVTPYEW--NLNFSCCTAHEPHPAAA 612

  Fly   360 -----------------------LLS--FGAGCIQG-AWLTPRSMGGRMAFFALMVTSYLMYNYY 398
                                   :||  ...||..| ..::.|.:||....|.|::.|....|..
 Worm   613 FATNQEAPIVMSNNYSFWNTVWYVLSTMLKGGCDFGPRAVSTRLLGGTWWVFYLVIISAYTANLA 677

  Fly   399 TSIVVSKLLGQPIKSNIRTLQQLADSNLDVGIEPTVYTRIYVETSEEPDVRDLYRKKVLGSKRSP 463
            ..:.||:.. .|||:    |..||:.           |.|...|.........:::..:.:.
 Worm   678 AVLTVSRPY-IPIKN----LDDLANQ-----------TTISYGTIRGGSTMQFFQESRIAAH--- 723

  Fly   464 DKIWIPTEAGVLSVRDQEGFVYITG------VATGYEFVRK----HFLAHQICELNEIPLRDASH 518
            .|:|       ..::|::.||...|      ::..|.::.:    .:...|.|.|.:|.....|.
 Worm   724 VKMW-------QYMKDKDVFVTSNGKGVERALSMNYAYLMESTSLEYETQQNCNLTQIGGVLGSK 781

  Fly   519 THTV-LAKRSPYAELIKLSELRMLETGVHFKHERSWMETK-------LHCYQHNHTVAVGLEYAA 575
            .:.: |||:|.:.:.|....|...:.|:....:..|..:|       ....:|:. .|:.:...|
 Worm   782 GYGIALAKKSEWTDRISRQILLYAKRGIIEMKKTKWWRSKGAACASTASAVKHDR-FALSMYNVA 845

  Fly   576 PLFIILLGAIILCMGILGLEVIWHR 600
            .|||.|...|:|...::..|:| ||
 Worm   846 GLFITLGVGIVLAAIVVIFELI-HR 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75b	NP_001137966.2	Periplasmic_Binding_Protein_Type_2	253..553	CDD:304360	67/351 (19%)
		Lig_chan	343..585	CDD:278489	56/297 (19%)
glr-5	NP_505244.1	PBP1_iGluR_delta_like	26..418	CDD:107376	45/244 (18%)
		ANF_receptor	38..377	CDD:279440	37/203 (18%)
		PBP2_iGluR_Kainate	438..819	CDD:270432	78/421 (19%)
		Lig_chan	568..855	CDD:278489	59/317 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810