Protein Alignment Ir75b and glr-1

DIOPT Version :9

• Sequence 1: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_498887.2
• Gene: glr-1 / 176204
• WormBaseID: WBGene00001612
• Length: 962
• Species: Caenorhabditis elegans
• Alignment Length: 771
• Identity: 155/771 - (20%)
• Similarity: 278/771 - (36%)
• Gaps: 233/771 - (30%)

  Fly     4 LHNLILHNLIHMAKLSHVLIL----HCSL------SHLALLAQSKNIFTQFQPLHSDIQLNDDFL 58
            :..|:...::|.. ...||:|    |.||      .||.....:....:.|.....:.|.....:
 Worm   149 ISELLADFIVHKG-WGEVLVLIDPVHASLHLPSLWRHLRTRTNTSVKASMFDLPADEKQFEAYLM 212

  Fly    59 NHNILKLGVFLDINCDKSGTVLDMASAKR------------FFSHRYHWLI-------YDRSM-- 102
            ..|:::       |.:.:..::|.||.||            |....||:::       ||:.|
 Worm   213 QFNMMR-------NNETNRILIDCASPKRLKKLLINIRSAQFNQANYHYVLANYDFLPYDQEMFQ 270

  Fly   103 -------NFSV----------LESHFKEA-------QIFVDA----DVTYVTHDPFSK----NFL 135
                   .|::          |:.|.|.:       .:.|:|    |...||...|:|    |..
 Worm   271 NGNINISGFNIINKDGREYWSLKKHLKTSSSLGGGDDVSVEAAVGHDAMLVTWHGFAKCLQANDS 335

  Fly   136 L--------------------------------YDVYNKGRQLG------------GEL--NITA 154
            |                                :..:..|:.:|            |.|  ||..
 Worm   336 LFHGTFRHRRFFNRGFPGIYCDPLSDRSHPNRPFSSFEHGKTIGVAFRNMKIGHKEGTLTGNIEF 400

  Fly   155 DREIFCNKTNCRVERYLSELYT-----------------------RSALQH-RKSFTGLTMRATA 195
            ||  |.|:.|..|.  :.:|.:                       |:..|| |||..........
 Worm   401 DR--FGNRKNFDVS--IVDLVSNTKATFNSKEVLAWRQGVGFFSNRTVAQHSRKSQNDHKDNQVI 461

  Fly   196 VVTAL--PLNVSIKEIFDFM-------NSKYRIQLDTYARLGY--QARQPLRDMLDCKFKYIFR- 248
            |:|.|  |..:..:|..:..       |:|:.         |:  ...:.|.|.:: :|.|..:
 Worm   462 VLTNLVAPFVMIKRECLEMANLTECQGNNKFE---------GFCIDLLKLLADKIE-EFNYEIKL 516

  Fly   249 -----DRWSDGNATGGMIGDLILDKADLAIAPFIYSFDRAL---FLQPI--TKFSVFREICMFRN 303
                 .:.:|| :..||||:|:..:|...:|....:.:|..   |.:|.  |..|:     |.:.
 Worm   517 GTKAGSKQADG-SWDGMIGELLSGRAHAVVASLTINQERERVVDFSKPFMTTGISI-----MIKK 575

  Fly   304 PRSVSAGLSATEFLQPFSGGVWLTFALLLLLAGCLLWVTFILERRK--QWKPS------------ 354
            |....  .|...|:||.|..:|:  .::....|..: |.|::.|..  :|:..
 Worm   576 PDKQE--FSVFSFMQPLSTEIWM--YIIFAYIGVSV-VIFLVSRFSPYEWRVEETSRGGFTISND 635

  Fly   355 -LLTSCL-LSFGAGCIQGAWLTPRSMGGRMA-----FFALMVTSYLMYNYYTSIVVSKLLGQPIK 412
             .:.:|| .:..|...||..:.|||:.||:|     ||.:::.|     .||:.:.:.|..:.::
 Worm   636 FSVYNCLWFTLAAFMQQGTDILPRSISGRIASSAWWFFTMIIVS-----SYTANLAAFLTLEKMQ 695

  Fly   413 SNIRTLQQLA-DSNLDVGIEPTVYTRIYVETSEEPDVRDLYRKKVLGSKRSPDKIWIPTEA-GVL 475
            :.|.:::.|| .|.:..||:....|..:.:.|.....:.::|  .:.|:..|  :::.:.| |:.
 Worm   696 APIESVEDLAKQSKIKYGIQGGGSTASFFKYSSVQIYQRMWR--YMESQVPP--VFVASYAEGIE 756

  Fly   476 SVRDQEG-FVY-ITGVATGYEFVRKHFLAHQI-CELNEIPLRDASHTHTVLAKRSPYAELIKLSE 537
            .||..:| :.: :...|..||..||.....:: ..||.|....|:      ...|.:.:.|.|:.
 Worm   757 RVRSHKGRYAFLLEATANEYENTRKPCDTMKVGANLNSIGYGIAT------PFGSDWKDHINLAI 815

  Fly   538 LRMLETGVHFKHERSWMETKLHC----YQHNHTVAVGLEYAAPLFIILLGAIILCM 589
            |.:.|.|...|.|..|...:..|    .....:.::.|...|.:|.||:|.:::.|
 Worm   816 LALQERGELKKLENKWWYDRGQCDAGITVDGSSASLNLSKVAGIFYILMGGMVISM 871

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75b	NP_001137966.2	Periplasmic_Binding_Protein_Type_2	253..553	CDD:304360	77/330 (23%)
		Lig_chan	343..585	CDD:278489	61/271 (23%)
glr-1	NP_498887.2	PBP1_iGluR_AMPA	10..439	CDD:107375	51/301 (17%)
		ANF_receptor	44..417	CDD:279440	50/279 (18%)
		Periplasmic_Binding_Protein_Type_2	457..832	CDD:304360	89/410 (22%)
		Lig_chan	593..867	CDD:278489	64/291 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810