Protein Alignment Ir75b and glr-3

DIOPT Version :9

• Sequence 1: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_492017.3
• Gene: glr-3 / 172449
• WormBaseID: WBGene00001614
• Length: 836
• Species: Caenorhabditis elegans
• Alignment Length: 574
• Identity: 114/574 - (19%)
• Similarity: 216/574 - (37%)
• Gaps: 139/574 - (24%)

  Fly    75 KSGTVLDMASAKRFF-------SHRYHWL-----------IYDRSMNFSVLESHFKEAQIFVDAD 121
            |||:.:    .||||       |...||.           :|.|:::|..........:....::
 Worm   325 KSGSDI----KKRFFENPLAGISGDLHWAPSGERSNYTLHVYRRTLSFQKFAEWSSRTRRIASSE 385

  Fly   122 VTYVTHDPFSKNFLLYDVYNKGRQLGGELNITADREIFCNKTNCRVERYLSELYTRSALQHRKSF 186
            ...:.:.  |:...|     :|:.|  ::::..:.......:|...|.|..:|.      |:
 Worm   386 AVVIANS--SEKLTL-----EGKHL--KISVYLEAPFVMITSNGSYEGYCIDLL------HK--- 432

  Fly   187 TGLTMRATAVVTALPLNVSIKEIFDFMNSKYRIQLDTYARLGYQARQPLRDMLDCKFKYIFRDRW 251
                     :...|....:|:::.|  |:             |.:::.             ..:|
 Worm   433 ---------IANILKFTYTIQKVRD--NA-------------YGSKES-------------NGKW 460

  Fly   252 SDGNATGGMIGDLILDKADLAIAPFIYSFDRALFLQPITKFSVFREICMFRNPRSVSAGLSATEF 316
            |      ||:|:|....||||:|....|:.|:..:.....:.......:|:.||...:  ...:|
 Worm   461 S------GMVGELQRGDADLAVASLTISYGRSEVIDFTVPYMHLGISILFKKPRIRDS--DWFKF 517

  Fly   317 LQPFSGGVW-LTFALLLLLAGCLLWVTFIL---------ERRKQWKP-----SLLTSCLLSFGAG 366
            :.|.|..|| :|||...::: ..:|:...:         |...|:||     ||..|...:..:.
 Worm   518 MDPLSTQVWIMTFASYFVVS-VAIWIIAKISPYEQFERDEDNGQYKPVDNQFSLRNSFWFTVCSL 581

  Fly   367 CIQGAWLTPRSMGGRMA-----FFALMVTSYLMYNYYTSIVVSKLLGQPIKS--NIRTLQQLADS 424
            ..||:.|.||:...|:.     ||||::.|....| ..:::.::.:..||::  ::....::...
 Worm   582 MQQGSELCPRAASTRLLTGIWWFFALILISSYTAN-LAAVLTTRRMETPIENADDLAAQTKIKYG 645

  Fly   425 NLDVGIEPTVYTRIYVETSEEPDVRDLYRKKVLGSKRSPDKIW--IPTEAGVLSVRDQEGFVYIT 487
            .|..|...:.:....:||.|                    ::|  :.:..|:.....:||...:.
 Worm   646 TLGRGSTMSFFNESKIETYE--------------------RMWQLMSSSPGLFVQSSKEGIARVK 690

  Fly   488 GVATGYEFVRK----HFLAHQICELNEI-PLRDASHTHTVLAKRSPYAELIKLSELRMLE-TGVH 546
              ::.|.::.:    .:...:.|||.:| .|.|.......|.|.|||.|||..:.||:.| |.:.
 Worm   691 --SSDYAYLMESSMLEYAVERDCELMQIGGLIDQKGYGIGLPKGSPYRELISTAILRLQEKTELT 753

  Fly   547 FKHERSWMETKLHCYQHNHTVAVGLEYAAPLFIILLGAIILCMGILGLEVIWHR 600
            ...|:.|.:..:.|.|.........|....:||||:..::|...::..|:|..|
 Worm   754 ELKEKWWKDKSVVCEQPKRKDQDDGESIGGIFIILVVGLVLTAVLVIFELITTR 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75b	NP_001137966.2	Periplasmic_Binding_Protein_Type_2	253..553	CDD:304360	73/329 (22%)
		Lig_chan	343..585	CDD:278489	58/270 (21%)
glr-3	NP_492017.3	PBP1_iGluR_non_NMDA-like	21..385	CDD:380591	13/63 (21%)
		Periplasmic_Binding_Protein_Type_2	401..761	CDD:419667	86/439 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810