Protein Alignment Ir75b and Grin2c

DIOPT Version :9

• Sequence 1: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_017169765.1
• Gene: Grin2c / 14813
• MGIID: 95822
• Length: 1307
• Species: Mus musculus
• Alignment Length: 448
• Identity: 96/448 - (21%)
• Similarity: 169/448 - (37%)
• Gaps: 110/448 - (24%)

  Fly   206 IKEIFDFMNSKYRIQLDTYARLGYQARQPLRDMLDCKFKYIFRDRWSDGNATGGMIGDLILDKAD 270
            :|::...:...|.:.|.|..:.|.:.                |..|:      ||||::...:||
Mouse   524 LKKLAKVVKFSYDLYLVTNGKHGKRV----------------RGVWN------GMIGEVYYKRAD 566

  Fly   271 LAIAPFIYSFDRALFLQPITKFSV-FRE----ICMFRNPRSVSAGLSATEFLQPFSGGVWLTFAL 330
            :||.....:.:|:    .|..||| |.|    :.:.|:..:|    |.:.||:|:|..||
Mouse   567 MAIGSLTINEERS----EIIDFSVPFVETGISVMVARSNGTV----SPSAFLEPYSPAVW----- 618

  Fly   331 LLLLAGCLLWVTFILERRKQWKPSLLTSCLL--------SFGAGCIQGAWL-------------T 374
            :::...||..|...:...:.:.|......|.        ||..|  :..||             .
Mouse   619 VMMFVMCLTVVAITVFMFEYFSPVSYNQNLTKGKKSGGPSFTIG--KSVWLLWALVFNNSVPIEN 681

  Fly   375 PRSMGGRM-----AFFALMVTSYLMYNYYTSIVVSKLLGQPIKSNIRTLQQLADSNLD------- 427
            ||....::     ||||::..:     .||:.:.:.::.:   ..|.|:..|:|....
Mouse   682 PRGTTSKIMVLVWAFFAVIFLA-----SYTANLAAFMIQE---QYIDTVSGLSDKKFQRPQDQYP 738

  Fly   428 ---VGIEPTVYTRIYVETSEEPDVRDLYRKKVLGSKRSPDKIWIPTEAGVLSV-RDQEGFVYITG 488
               .|..|...|    |.:...:.||::...|..::||.:......:.|...| |..:.|:|...
Mouse   739 PFRFGTVPNGST----ERNIRSNYRDMHTHMVKFNQRSVEDALTSLKMGARHVSRKLDAFIYDAA 799

  Fly   489 VATGYEFVRKHFLA--HQICELNEIPLRDASHT---HTVLAKRSPYAELIKLSELRMLETGVHFK 548
            |.        :::|  .:.|:|..|.......|   ...:.|.|.:...|.|:.|:.|..|...|
Mouse   800 VL--------NYMAGKDEGCKLVTIGSGKVFATTGYGIAMQKDSHWKRAIDLALLQFLGDGETQK 856

  Fly   549 HERSWMETKLHCYQHNHTVA--VGLEYAAPLFIILLGAIILCMGILGLE--VIWH-RH 601
            .|..|:....| .:.|..::  :.::..|.:|.:||.|:.|.:.:...|  |.|. ||
Mouse   857 LETVWLSGICH-NEKNEVMSSKLDIDNMAGVFYMLLVAMGLALLVFAWEHLVYWKLRH 913

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75b	NP_001137966.2	Periplasmic_Binding_Protein_Type_2	253..553	CDD:304360	75/346 (22%)
		Lig_chan	343..585	CDD:278489	55/285 (19%)
Grin2c	XP_017169765.1	PBP1_iGluR_NMDA_NR2	90..446	CDD:380601
		PBP2_iGluR_NMDA_Nr2	462..868	CDD:270436	84/401 (21%)
		NMDAR2_C	905..>980	CDD:371139	4/9 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846361
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830