Protein Alignment Ir75b and LOC1275780

DIOPT Version :10

• Sequence 1: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_315067.5
• Gene: LOC1275780 / 1275780
• VectorBaseID: AGAMI1_007352
• Length: 622
• Species: Anopheles gambiae
• Alignment Length: 588
• Identity: 133/588 - (22%)
• Similarity: 243/588 - (41%)
• Gaps: 102/588 - (17%)

  Fly    60 HNILKLGVFLDINCD----KSGTVLDMASAKRFFSHRYHWLIYDRSM--NFSVLESHFKEAQIFV 118
            :.:.:.|:.:|.:|:    .....:|....|..:.: .||||.::.:  ..|:....:...|:.:
Mosquito    67 NRVSQAGLLIDASCEIEPISKLWQMDQLLNKLLYGN-LHWLIVEKQLPVKRSIDSGPYSSDQLEL 130

  Fly   119 -------DADVTYVTH-----DPFSKNFLLYDVYNKGRQLGGELNITADREIFCNKTNCRVERYL 171
                   ..||...|:     ...|.::.|:::|...|:  ..|::.   .|..|.... |:||.
Mosquito   131 LYNERLRPLDVMPYTNVVLAFQKISDSWELFELYKPYRK--ARLSVV---NIASNYLPA-VDRYG 189

  Fly   172 SELYTRSAL-QHRKSFTGLTMRATAVVTA---------------------LPLNVSIKEI-FDFM 213
            |:|..|..| ..|::..|..|......|:                     .|.   |:|: :|..
Mosquito   190 SQLIVRRKLVDRRRNLQGFAMPCGTATTSPEYFTGMDDRNDVHDLFTKANFPF---IRELMYDLN 251

  Fly   214 NSKYRIQLDTYARLGYQARQPLRDMLDCKFKYIFRDRWSDGNATGGMIGDLI----LDKADLAIA 274
            .:...:|||   ::||:.......::         .::.:.:...|.:|.|:    |:.||..|.
Mosquito   252 FTLNMVQLD---KVGYKQNGTFSGVM---------GKFQNRSIELGCLGTLMRTERLEVADFMIV 304

  Fly   275 PFIYSFDRALFLQPITKFSVFREICMFRNPRSVSAGLSATEFLQPFSGGVW-LTFALLLLLAGCL 338
            ..|.. ...:|.||               |.|:.|.:    |..|||.||| ..|||:     .:
Mosquito   305 TLIIK-SSIIFRQP---------------PLSIVANI----FELPFSVGVWACCFALM-----AI 344

  Fly   339 LWVTFILERR--KQWKPSLLTSCLLSFGAGCIQGAWLTPRSMGGRMAFFALMVTSYLMYNYYTSI 401
            .|:|.|..|:  ...:...:.|.:...|..|.:|..:.|:..|.|:..|:|.:||:.:...|::.
Mosquito   345 YWMTMIAIRQLTSGERFGAIESLVYIIGTMCQRGCDIVPQFNGTRLLMFSLQLTSFFILTSYSAS 409

  Fly   402 VVSKLLGQPIKSNIRTLQQLADSNLDVGIEPTVYTRIYVETSEEPDVRDLYRKKVLGSKRSPDKI 466
            :|: ||..|.:: |.::..|..|.|..|:..|.|.|:|.:.:::|||::|||||:   |...:|.
Mosquito   410 IVA-LLQSPSRA-IASVGDLVRSPLKAGVMDTSYGRVYYQETQDPDVQELYRKKI---KPHGEKA 469

  Fly   467 WIPTEAGVLSVRDQEGFVYITGVATGYEFVRKHFLAHQICELNEIPLRDASHTHTVLAKRSPYAE 531
            ::....|:..|: ||.:.|...:...|:.:::.|...::|:|.|:...........:.|.|.|.|
Mosquito   470 FLEPNEGIGRVK-QEMYAYEGELNAAYKVIKETFAPEEVCKLQELEAIKLPPFGIPIVKGSKYRE 533

  Fly   532 LIKLSELRMLETGVHFKHERSWMETKLHCYQHNHTV-AVGLEYAAPLFIILLGAIILCMGILGLE 595
            ||:...:...|.|:..:....|:..|..|...|... :||:.....|::.|....:..:..|..|
Mosquito   534 LIRQRLMWQREVGIIKRFNLIWIHQKPQCENLNAGFSSVGVVEMRYLYLFLAVGFLAALATLLAE 598

  Fly   596 VIW 598
            ..|
Mosquito   599 RSW 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75b	NP_001137966.2	Lig_chan-Glu_bd	<235..283	CDD:463166	8/51 (16%)
		Periplasmic_Binding_Protein_Type_2	<259..>325	CDD:473866	19/69 (28%)
		Lig_chan	343..584	CDD:459656	63/243 (26%)
LOC1275780	XP_315067.5	None