Protein Alignment Ir75b and grin3b

DIOPT Version :9

• Sequence 1: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_017952374.2
• Gene: grin3b / 100497172
• XenbaseID: XB-GENE-990106
• Length: 1005
• Species: Xenopus tropicalis
• Alignment Length: 701
• Identity: 123/701 - (17%)
• Similarity: 227/701 - (32%)
• Gaps: 247/701 - (35%)

  Fly    73 CD--KSGTVLDMASAKRFFSHRYHWLIYDRSMNFSVLESHFKEAQIFVDADVTYVTHDPFSKNFL 135
            ||  :|..|..:|......:|.:||:| ...:|...:.:......:....:|:..|.:.|.::.:
 Frog   236 CDARRSSLVFRVARDCGLEAHEFHWMI-GHPLNGEEMTTEGMPPGLLAYGEVSRPTMEKFIRDAV 299

  Fly   136 LYDVYNKG---RQLGGELNITADREIFCNKTNCR-------------VERYLS---------ELY 175
                   |   |.:...:::..|..:..:..||.             :.|:|:         ::|
 Frog   300 -------GLVTRAISAAVHVRPDLALIQSMVNCNDKQTKQNESSGSYLSRFLANTSFSGQTGQIY 357

  Fly   176 TRSALQHRK------------------------------------------------SFTGLTMR 192
            ..:.|.|.:                                                .|....:|
 Frog   358 VSNNLIHTEHHYRIWSLVRDSLGDPTWVTVGGWRQGKMEVEEGLWQSRIQQWEPAPGGFARTKLR 422

  Fly   193 ATAVV----------------------------TALPLNVSIKEI--------FDFMNSKYRIQL 221
            ...:|                            .:..|:|..:|:        .::....|...:
 Frog   423 VVTLVEHPFVFTREVDADGSCPAGQMCLDPRTNNSAVLDVLFEELNSPNGSVPLEYKTCCYGYCI 487

  Fly   222 DTYARLGYQARQPLRDMLDCKFKYIFR--DRWSDGNATGGMIGDLILDKADLAIAPFIYSFDRAL 284
            |...:|....|......:....||..|  |||:      |::|||:...|.:|:..|..:..|:.
 Frog   488 DLLEKLSEDLRFDFELYIVGDGKYGARKGDRWT------GLVGDLLSGAAHMAVTSFSINSARST 546

  Fly   285 ---FLQPITKFSVFREICMFRNPRSVSAGLSATEFLQPFSGGVWL-TFALLLLLAGCLLWVTFIL 345
               |..|....|:...:.|    |..::.:.|  |:.|....:|: .|..|.:.|   |::||.
 Frog   547 VIDFTSPFYSTSLGILVRM----RDTASPIGA--FMWPLHWSMWVGIFVALHITA---LFLTFY- 601

  Fly   346 ERRKQWK------------------PSLLTSC-LLSFGAGCIQGAWLTPRSMGGRM-----AFFA 386
                :||                  .|.|..| .:.||...   :..||:...||:     |.|.
 Frog   602 ----EWKSPFGMTPHGRNRTKIFSYSSALNLCYAILFGRTV---SSKTPKCCTGRVLMNLWAIFC 659

  Fly   387 LMVTSYLMYNYYTSIVVSKLLGQPIKSNIRTLQQLADSNLDVGIEPTVYTRIYVETSEE------ 445
            |:|.|     .||:.:.:.::|.   .....|..:.|..|....:...:..::..::|:
 Frog   660 LLVLS-----SYTANLAAVMVGD---KTFEALSGIHDPKLHHPSQGFRFGTVWESSAEQYIKKSF 716

  Fly   446 PDVRDLYRKKVLGSKRSPDKIWIP-TEAGVLSVRDQEGFVYITGVATGYEFVR-KHFLAHQI--- 505
            |::.:..|           |..:| |..||..::        |...|...|:. |..|.:::
 Frog   717 PEMHNYMR-----------KFSVPATSDGVHLLK--------TDPPTLNAFIMDKALLDYEVSID 762

  Fly   506 --CELNEIPLRDASHTHTV-LAKRSPYAELIKLSELRMLETGVHFKHERSWMETKLH-------- 559
              |:|..|....|...:.: |.:.||....|.....|...:|        :|:| ||
 Frog   763 SDCKLLTIGKPFAIEGYGIGLPQNSPLTSNISEFISRYKSSG--------FMDT-LHDKWYKMVP 818

  Fly   560 C----YQHNHTVAVGLEYAAPLFIILLGAIILCMGILGL-------EVIWH 599
            |    |....|:.:|:.:.:.||      ::||:|..|.       .|::|
 Frog   819 CGKRVYAVTETLQMGIYHFSGLF------VLLCIGFCGSLLTSLMERVVYH 863

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75b	NP_001137966.2	Periplasmic_Binding_Protein_Type_2	253..553	CDD:304360	68/341 (20%)
		Lig_chan	343..585	CDD:278489	56/291 (19%)
grin3b	XP_017952374.2	PBP1_iGluR_NMDA_NR3	29..402	CDD:380600	23/173 (13%)
		PBP2_iGluR_NMDA_Nr3	418..814	CDD:270438	87/454 (19%)
		Lig_chan	582..848	CDD:395014	64/318 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910