Protein Alignment Ir75b and grik1

DIOPT Version :10

• Sequence 1: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_004912220.1
• Gene: grik1 / 100493949
• XenbaseID: XB-GENE-957124
• Length: 928
• Species: Xenopus tropicalis
• Alignment Length: 572
• Identity: 120/572 - (20%)
• Similarity: 204/572 - (35%)
• Gaps: 154/572 - (26%)

  Fly    58 LNHNILKLGVFLDINCDKSGTVLDMASAKRFFSHRYHWLIYDRSMNFSVLESHFKEAQIFVDADV 122
            ||....|:||:      .|.|.|:|...           :.|:|.|  :.:|......|     |
 Frog   419 LNKVWKKVGVW------NSNTGLNMTDN-----------LKDKSTN--ITDSLANRTLI-----V 459

  Fly   123 TYVTHDPFSKNFLLYDVYNKGRQLGGELNITADREIFCNKTNCRVERYLSELYTRSALQHRKSFT 187
            |.:..||       |.::.|           :|:.::.|.   |.|.|..:|
 Frog   460 TTILEDP-------YVMFRK-----------SDKPLYGND---RFEGYCLDL------------- 490

  Fly   188 GLTMRATAVVTALPLNVSIKEIFDFMNSKYRIQLDTYARLGYQARQPLRDMLDCKFKYIFRDRWS 252
                              :||:.:.:...|.::|....:.|.|                     :
 Frog   491 ------------------LKELSNILGFTYEVRLVVDGKYGAQ---------------------N 516

  Fly   253 DGNATGGMIGDLILDKADLAIAPFIYSFDRALFLQPITKFSVFREICMFRNPRSVSAGLSATEFL 317
            |.....||:.:||..|||||:||...::.|...:.....|.......::|.|...:.|:.:  ||
 Frog   517 DKGEWNGMVRELIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFS--FL 579

  Fly   318 QPFSGGVWLTFALLLLLAGCLLWVTFILERRKQWKP--------------SLLTSCLLSFGAGCI 368
            .|.|..:|:...|..|...|:|:|.......:.:.|              :||.|.....||...
 Frog   580 NPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQ 644

  Fly   369 QGAWLTPRSM-----GGRMAFFALMVTSYLMYNYYTSIVVSKLLGQPIKSNIRTLQQLADSNLDV 428
            ||:.|.|:::     ||...||.|::.|     .||:.:.:.|..:.::|.|.:...||..
 Frog   645 QGSELMPKALSTRIVGGIWWFFTLIIIS-----SYTANLAAFLTVERMESPIDSADDLAKQ---- 700

  Fly   429 GIEPTVYTRIYVETSEEPDVRDLYRKKVLGSKRSPDKIWIPTEAGVLSVRDQ--------EGF-- 483
                   |:|......:......::|..:.:.   :|:|     ..:|.|.|        ||.
 Frog   701 -------TKIEYGAVRDGSTMTFFKKSKISTY---EKMW-----AFMSSRQQTALVKNNDEGIQR 750

  Fly   484 VYITGVATGYEFVRKHFLAHQICELNEI-PLRDASHTHTVLAKRSPYAELIKLSELRMLETG-VH 546
            |..|..|...|.....::..:.|.|.:| .|.|:..........|||.:.|.::.|::.|.| :|
 Frog   751 VLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLH 815

  Fly   547 FKHERSWMETKLHCYQHNHTVAVGLEYAAPLFIILLGAIILCMGILGLEVIW 598
            ...|:.|..............|:|:|....:||:|...::|.:.:...|.|:
 Frog   816 MMKEKWWRGNGCPEEDSKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIY 867

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75b	NP_001137966.2	Lig_chan-Glu_bd	<235..283	CDD:463166	12/47 (26%)
		Periplasmic_Binding_Protein_Type_2	<259..>325	CDD:473866	20/65 (31%)
		Lig_chan	343..584	CDD:459656	58/271 (21%)
grik1	XP_004912220.1	PBP1_iGluR_Kainate	46..439	CDD:380605	9/25 (36%)
		Periplasmic_Binding_Protein_Type_2	454..823	CDD:473866	97/472 (21%)