DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir75b and LOC100334689

DIOPT Version :9

Sequence 1:	NP_001137966.2	Gene:	Ir75b / 8673994	FlyBaseID:	FBgn0261402	Length:	605	Species:	Drosophila melanogaster
Sequence 2:	XP_017206939.1	Gene:	LOC100334689 / 100334689	-ID:	-	Length:	991	Species:	Danio rerio

Alignment Length:	576	Identity:	127/576 - (22%)
Similarity:	215/576 - (37%)	Gaps:	148/576 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 HRYH-WLIYDRSMNFSVLESHF------------KEAQIFVDADVTYVTHDPFSKNFLLYDVYNK 142
            ||:. |....|.|:| :.|||:            ...:...|.|:..:..|...|       ..|
Zfish   344 HRHKPWRFGGRFMSF-IKESHWDGLTGRLCFNRTTGLRTDFDLDIVSLKEDGLQK-------VGK 400

  Fly   143 GRQLGGELNIT-ADREIFCNKTNCRVER------YLSELY-----TRSALQHRKSFTGLTMRATA 195
            ....|| |||| ..|:...|.|:....|      .|.|.|     :..||.....|.|..:..
Zfish   401 WSASGG-LNITEVPRQNGMNITDSLSNRSLVITTILEEPYVMLKKSDKALVGNDRFEGFCIDL-- 462

  Fly   196 VVTALPLNVSIKEIFDFMNSKYRIQLDTYARLGYQARQPLRDMLDCKFKYIFRDRWSDGNATGGM 260
                      :||:...:...|.|.|....:.|:|                     .|.....||
Zfish   463 ----------LKELASILGFSYEIHLVPDGKYGFQ---------------------DDKGQWNGM 496

  Fly   261 IGDLILDKADLAIAPFIYSF--DRAL-FLQPI--TKFSVFREICMFRNPRSVSAGLSATEFLQPF 320
            |.:|:..:||||:||...:|  ::|: |.:|.  |..|:     ::|.|.|.::|..:  ||.|.
Zfish   497 IRELMEHRADLAVAPLTITFMREKAIDFSKPFLNTGISI-----LYRKPNSTNSGFFS--FLNPM 554

  Fly   321 SGGVWLTFALLLLLAGCLLWVTFILERRK--QW------KP---------SLLTSCLLSFGAGCI 368
            :..:|:...|..|...|:|   |::.|..  :|      .|         :||.|  ..||.|.:
Zfish   555 TPDIWVYILLAYLGVSCVL---FVIARFSPYEWYDAHPCNPGSDVVENNFTLLNS--FWFGVGSL 614

  Fly   369 --QGAWLTPRSM-----GGRMAFFALMVTSYLMYNYYTSIVVSKLLGQPIKSNIRTLQQLADSNL 426
              ||:.|.|:::     ||...||.|::.|....|....:.|.::                ||.:
Zfish   615 MQQGSELMPKALSTRIIGGIWWFFTLIIISSYTANLAAFLTVERM----------------DSPV 663

  Fly   427 DVGIEPTVYTRIYVETSEEPDVRDLYRKKVLGSKRSPDKIWIPTEAGVLSVRDQEGFVYITGVAT 491
            |...:....|:|.....::......::|..:.:.   :|:|     ..:|.|....||  ..:..
Zfish   664 DSADDLAKQTKIEYGVVKDGATMSFFKKSRVSTF---EKMW-----AFMSSRQSTSFV--KSIED 718

  Fly   492 GYEFVRK------------HFLAHQICELNEI-PLRDASHTHTVLAKRSPYAELIKLSELRMLET 543
            |.:.|.|            .::..:.|.|.:: .:.|:........|.|||.:.|.::.|.:||.
Zfish   719 GIQRVLKSDYALLMESTTIEYVTRRNCNLTQVGGIIDSKGYGIGTPKGSPYRDKITIAILGILED 783

  Fly   544 G-VHFKHERSWMETKLHCYQHNHTVAVGLEYAAPLFIILLGAIILCMGILGLEVIW 598
            | :|...|:.|..:.....:...|..:|::....:||:|...::|.:.:...|.|:
Zfish   784 GRLHMLKEKWWSGSSCLEDERYETGPMGIQNLGGIFIVLASGLVLSVFVAIGEFIY 839

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir75b	NP_001137966.2	Periplasmic_Binding_Protein_Type_2	253..553	CDD:304360	80/342 (23%)
Ir75b	NP_001137966.2	Lig_chan	343..585	CDD:278489	57/279 (20%)
LOC100334689	XP_017206939.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591226
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740