Protein Alignment Ir75b and grin2cb

DIOPT Version :10

• Sequence 1: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_009305071.3
• Gene: grin2cb / 100333648
• ZFINID: ZDB-GENE-100308-2
• Length: 1328
• Species: Danio rerio
• Alignment Length: 624
• Identity: 123/624 - (19%)
• Similarity: 223/624 - (35%)
• Gaps: 182/624 - (29%)

  Fly    48 HSDIQLNDD--FLNHNILKLGVFLDINCDKSGT----VLDMASAKRFFSHRYH-WLIY------- 98
            |.|:..|.|  ..|.:::.:.:..:.:.||.|:    :|.|         ||. |..|
Zfish   349 HKDLSFNSDGYLTNPSMVIIALDRENHWDKVGSYEGGILQM---------RYPVWPRYGSFLEPV 404

  Fly    99 --DRSMNFSVLESHFKEAQIFVDADVTYVTHDPFSKNFLLYDVYNKGRQLGGELNITADREIFCN 161
              :|.:..:.||.     :.||..:    :.||                        |......|
Zfish   405 SDNRHLTVATLEE-----RPFVIVE----SVDP------------------------ATGTCVRN 436

  Fly   162 KTNCRVERYLSELYTRSALQHRKSFTGLTMRATAVVTALPLNVSIKEIFDFMNSKYRIQLDTYAR 226
            ...||.:...:|    |.:.|.:.:|.|..:...:.....|:.:||..:|       :.|.|..:
Zfish   437 TVPCRRQSNRTE----SIIGHTEPYTKLCCKGFCIDILKKLSRTIKFSYD-------LYLVTNGK 490

  Fly   227 LGYQARQPLRDMLDCKFKYIFRDRWSDGNATGGMIGDLILDKADLAIAPFIYSFDRALFLQPITK 291
            .|                .:.|..|:      ||||::...:||:||.....:.:|:    .|..
Zfish   491 HG----------------KMVRGVWN------GMIGEVFYKRADMAIGSLTINEERS----EIVD 529

  Fly   292 FSV-FRE----ICMFRNPRSVSAGLSATEFLQPFSGGVWLTFALLLLLAGCLLWV---TFILERR 348
            ||| |.|    :.:.|:..:|    |.:.||:|:|..||     :::...||..|   .|:.|
Zfish   530 FSVPFVETGISVMVARSNGTV----SPSAFLEPYSPAVW-----VMMFVMCLTVVAVTVFVFE-- 583

  Fly   349 KQWKPSLLTSCLLS--------FGAGCIQGAWL-------------TPRSMGGRM-----AFFAL 387
             .:.|......|:|        |..|  :..||             .|:....::     ||||:
Zfish   584 -YFSPVGYNRSLVSAKAPGGPTFTIG--KSVWLLWGIVFNNSVPIENPKGTTSKIMVLVWAFFAV 645

  Fly   388 MVTSYLMYNYYTSIVVSKLLGQPIKSNIRTLQQLADSNLDVGIE--PTVYTRIYVETSEEPDVR- 449
            :..:     .||:.:.:.::.:   ..|.|:..|:|.......|  |..........|.|.::|
Zfish   646 IFLA-----SYTANLAAFMIQE---QYIDTVSGLSDKKFQKPQEHYPPFRFGTVPNGSTERNIRS 702

  Fly   450 ---DLYRKKVLGSKRSPDKIWIPTEAGVLSVRDQEGFVYITGVATGYEFVRKHFLA--HQICELN 509
               |::...:..:::..::.....:.|.|     :.|:|...|.        :::|  .:.|:|.
Zfish   703 NYPDMHTHMIKYNQKGVEEALNSLKTGKL-----DAFIYDAAVL--------NYMAGKDEGCKLV 754

  Fly   510 EIPLRDASHT---HTVLAKRSPYAELIKLSELRMLETGVHFKHERSWMETKLHCYQHNHTV---A 568
            .|.......|   ...|.|.|.:...|.|:.|:.|..|...:.|..|:..  .|....:.|   .
Zfish   755 TIGSGKVFATTGYGIALQKDSRWKRPIDLALLQFLGDGDTQRLETVWLSG--ICQNEKNEVMSSK 817

  Fly   569 VGLEYAAPLFIILLGAIILCMGILGLE--VIWHRHCTLH 605
            :.::..|.:|.:||.|:.|.:.:...|  :.|....::|
Zfish   818 LDIDNMAGVFYMLLVAMGLSLLVFAWEHLLYWKLRHSVH 856

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75b	NP_001137966.2	Lig_chan-Glu_bd	<235..283	CDD:463166	10/47 (21%)
		Periplasmic_Binding_Protein_Type_2	<259..>325	CDD:473866	22/70 (31%)
		Lig_chan	343..584	CDD:459656	52/280 (19%)
grin2cb	XP_009305071.3	None