Protein Alignment Ir75b and si:ch211-264f5.8

DIOPT Version :10

• Sequence 1: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_017207885.1
• Gene: si:ch211-264f5.8 / 100331381
• ZFINID: ZDB-GENE-081104-209
• Length: 1063
• Species: Danio rerio
• Alignment Length: 741
• Identity: 158/741 - (21%)
• Similarity: 270/741 - (36%)
• Gaps: 200/741 - (26%)

  Fly     1 MLQLHNLILHNLIHMAKLSHVLILHCSLSHLALLAQSKNIFTQFQPLHSDIQLNDDFLNHNILKL 65
            :|:|..|:.|.||....|| |.:|..:|....||.                ::.||       |:
Zfish   183 LLRLEELVRHFLISRETLS-VRMLDENLDPTPLLK----------------EIRDD-------KV 223

  Fly    66 G-VFLDINCDKSGTVLDMASAKRFFSHRYHWLIYDRSMNFSV--LESHFKEAQIFVDADVTYVTH 127
            . :.:|.|...|..:|..||.....|..|.:::  .:|:|.:  |:....:....|...:...:|
Zfish   224 ATIIIDANASVSILILKKASELGMTSAFYKYIL--TTMDFPLLRLDDVVNDQSNIVGFSMLNNSH 286

  Fly   128 DPFSKNF-------------------------LLYDV----------YNKGRQLGGE-LNITAD- 155
             ||...|                         |::|.          .|:.:::|.: |:.|:.
Zfish   287 -PFYLEFIRSLNLSWREGCDLSPYPGPALSSALMFDAVHVVVGAVRELNRSQEIGVKPLSCTSSL 350

  Fly   156 ------------REIFCNKTNCRVERYLSELYTRSALQHRKSFTG-------------LTMRATA 195
                        |.:..:....|||.......|...|:..:.|.|             |.|.:|:
Zfish   351 IWQHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILEKFKGGHKEIGVWYSNNTLAMNSTS 415

  Fly   196 V--------------VTALPLN--VSIKEIF-DFMNSKYRIQLDTYARLGYQARQPLRDMLDCKF 243
            :              ||.:..|  |..||.: ||..|      |.|........:.|.|:|
Zfish   416 LDINTSETLANKTLTVTTILENPYVMRKENYQDFQGS------DQYEGFCVDMLRELADIL---- 470

  Fly   244 KYIFRDRWSDGNATG---------GMIGDLILDKADLAIAPFIYSFDRAL---FLQPITK--FSV 294
            |:.||.:..|....|         ||:|:||..|||||:|.|..:.:|..   |.:|...  .|:
Zfish   471 KFSFRIKLVDDGLYGAPEPNGSWTGMVGELINRKADLAVAGFTITSEREKVIDFSKPFMNLGISI 535

  Fly   295 FREICMFRNPRSVSAGLSATEFLQPFSGGVWLTFALLLLLAGCLLWVTFILERRKQWKP------ 353
            ...:.:.|.|...|       ||.|||..|||...|..|...|:|::...|...:.:.|
Zfish   536 LYRVHIGRKPGYFS-------FLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPFPCWRE 593

  Fly   354 ---------SLLTSCLLSFGAGCIQGAWLTPRSMGGR------MAFFALMVTSYLMYNYYTSIVV 403
                     :|..|.....|....||:.:.||::..|      .||..::::|      ||:.:.
Zfish   594 RRDLLENQYTLGNSLWFPIGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISS------YTANLA 652

  Fly   404 SKLLGQPIKSNIRTLQQLAD-SNLDVGIEPTVYTRIYVETSEEPDVRDLYRKKVLGSKRSPDKIW 467
            :.|..|.::..|.:.:.||| :|:..|......|..:...|.....:.::  ..:.||: |....
Zfish   653 AFLTVQRMEVPIESAEDLADQTNIQYGTIQGGSTMTFFMNSRYQTYQRMW--NYMYSKQ-PSVFV 714

  Fly   468 IPTEAGVLSVRDQEGFVYITGVATGYEFVRKHFLAHQICELNEI-PLRDASHTHTVLAKRSPYAE 531
            ..||.|:..|.:.: :.::. .:|..|:.|:     ..|.|.:| .|.|.......:...||:.:
Zfish   715 KSTEEGIARVLNSK-YAFLL-ESTMNEYHRR-----LNCNLTQIGGLLDTKGYGIGMPLGSPFRD 772

  Fly   532 LIKLSELRMLETGVHFKHERSWMETKLHCYQHNHTV-AVGLEYAAPLFIILLGAIILCMGILGLE 595
            .|.|..|::.|.......:|.|.|......:.:|.. .:|::....:|::|:..:|:.:.:..:|
Zfish   773 EITLGILQLQENNRLEILKRRWWEGGKCLKEEDHRAKGLGMDNIGGIFVVLICGLIIAVFVAIME 837

  Fly   596 VIW--------------------HRH 601
            .:|                    |||
Zfish   838 FVWSTRRSAETDEVRPHPCPVRNHRH 863

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75b	NP_001137966.2	Lig_chan-Glu_bd	<235..283	CDD:463166	20/56 (36%)
		Periplasmic_Binding_Protein_Type_2	<259..>325	CDD:473866	24/70 (34%)
		Lig_chan	343..584	CDD:459656	53/264 (20%)
si:ch211-264f5.8	XP_017207885.1	PBP1_iGluR_Kainate_KA1_2	35..413	CDD:380616	48/256 (19%)
		Periplasmic_Binding_Protein_Type_2	426..796	CDD:473866	98/402 (24%)