Protein Alignment Ir75b and gria1

DIOPT Version :10

• Sequence 1: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_004912781.1
• Gene: gria1 / 100127569
• XenbaseID: XB-GENE-995621
• Length: 903
• Species: Xenopus tropicalis
• Alignment Length: 463
• Identity: 110/463 - (23%)
• Similarity: 183/463 - (39%)
• Gaps: 93/463 - (20%)

  Fly   188 GLTMRATAVVTALPL-NVSIKEIFDFMNSKYRIQLDTYARLGYQARQPLRDMLDCKFKY---IFR 248
            |:..|...|.|.|.. .|.:|:..|.:....|.:       ||.............|||   |.:
 Frog   404 GVQNRTYIVTTILEAPYVMLKKNADQLEGNDRFE-------GYCVELAAEIAKHVGFKYKLEIVK 461

  Fly   249 D-----RWSDGNATGGMIGDLILDKADLAIAPFIYSFDRAL---FLQPITKFSVFREICMFRNPR 305
            |     |.||..|..||:|:|:..:||||:||...:..|..   |.:|.....:   ..|.:.|:
 Frog   462 DGKYGARDSDMKAWNGMVGELVYGRADLAVAPLTITLVREEVIDFSKPFMSLGI---SIMIKKPQ 523

  Fly   306 SVSAGLSATEFLQPFSGGVWLTFALLLLLAGCLLW-------VTFILERRK--QW---------- 351
            ....|:.:  ||.|.:..:|:          |:::       |.|::.|..  :|
 Frog   524 KSKPGVFS--FLDPLAYEIWM----------CIVFAYIGVSVVLFLVSRFSPYEWHNEEFEEGKE 576

  Fly   352 KPS--------LLTSCLLSFGAGCIQGAWLTPRSMGGRMA-----FFALMVTSYLMYNYYTSIVV 403
            :|:        :..|...|.||...||..::|||:.||:.     ||.|::.|....|....:.|
 Frog   577 QPTTDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV 641

  Fly   404 SKLLGQPIKS--NIRTLQQLADSNLDVGIEPTVYTRIYVETSEEPDVRDLYRKKVLGSKRS--PD 464
            .::: .||:|  ::....::|...||.|.....:.|..:...|          |:....||  |.
 Frog   642 ERMV-SPIESADDLAKQTEIAYGTLDSGSTKEFFKRSKIAVFE----------KMWTYMRSAEPS 695

  Fly   465 KIWIPTEAGVLSVRDQEG-FVYITGVATGYEFVRKHFLAHQICELNEIPLR-DASHTHTVLAKRS 527
            .....||.|:..||..:| :.|:. .:|..|::.:    .:.|:..::... |:........|.|
 Frog   696 VFVKTTEEGMNRVRKSKGKYAYLL-ESTMNEYIEQ----RKPCDTMKVGGNLDSKGYGIATPKGS 755

  Fly   528 PYAELIKLSELRMLETGVHFKHERSWMETKLHC-----YQHNHTVAVGLEYAAPLFIILLGAIIL 587
            |....:.|:.|::.|.||..|.:..|...|..|     ...:.|.|:.|...|.:|.||:|.:.|
 Frog   756 PLRGAVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGL 820

  Fly   588 CMGILGLE 595
            .|.:..:|
 Frog   821 AMLVALIE 828

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75b	NP_001137966.2	Lig_chan-Glu_bd	<235..283	CDD:463166	19/55 (35%)
		Periplasmic_Binding_Protein_Type_2	<259..>325	CDD:473866	19/68 (28%)
		Lig_chan	343..584	CDD:459656	64/276 (23%)
gria1	XP_004912781.1	PBP1_iGluR_AMPA_GluR1	26..393	CDD:380613
		PBP2_iGluR_AMPA_GluR1	407..788	CDD:270447	97/418 (23%)