DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nost and cd2ap

DIOPT Version :9

Sequence 1:	NP_001285029.1	Gene:	Nost / 8673992	FlyBaseID:	FBgn0259734	Length:	1330	Species:	Drosophila melanogaster
Sequence 2:	NP_001008583.2	Gene:	cd2ap / 494040	ZFINID:	ZDB-GENE-030131-8078	Length:	657	Species:	Danio rerio

Alignment Length:	156	Identity:	40/156 - (25%)
Similarity:	75/156 - (48%)	Gaps:	30/156 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly  1193 DRGQADGGSNQQDSDF-DEFSSQDEDDEPQQPQQQPQPLQSQQQQQQPLLQ---NPTINGQVQTQ 1253
            :.|..:|..|.:...| |.|..:...|||:..::..:|.::::.:::..:|   :..:...||..
Zfish    34 EEGWMEGDLNGKRGLFPDNFVKEVRKDEPKSKEESKEPKEAKEVKEESTIQRRASGNVASLVQRI 98

  Fly  1254 HFY----------------QNAQELQKGQKNGSVPILGRCKALYSYTPKLYDELELSPGDIIEVH 1302
            ..|                .:.::|:|.|          ||.|:.|.|:..|||||..|:|||:.
Zfish    99 STYGIPAGGIGLQPHSQPRASKKKLKKRQ----------CKVLFEYVPQNEDELELKVGEIIEIT 153

  Fly  1303 AKQDDGWWLGALRNHIGIFPATYVEE 1328
            .:.::|||.|::....|:||:.:|:|
Zfish   154 EEVEEGWWSGSMNGKSGLFPSNFVKE 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nost	NP_001285029.1	F-BAR_NOSTRIN	663..908	CDD:153342
Nost	NP_001285029.1	SH3_Nostrin	1276..1328	CDD:212757	22/51 (43%)
cd2ap	NP_001008583.2	SH3_CD2AP_1	12..58	CDD:212986	6/23 (26%)
		SH3_CD2AP_2	126..180	CDD:212987	24/64 (38%)
		SH3_CD2AP_3	285..341	CDD:212989
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1577081at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14167
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.110