Protein Alignment Nost and C36E8.4

DIOPT Version :9

• Sequence 1: NP_001285029.1
• Gene: Nost / 8673992
• FlyBaseID: FBgn0259734
• Length: 1330
• Species: Drosophila melanogaster
• Sequence 2: NP_497805.2
• Gene: C36E8.4 / 183279
• WormBaseID: WBGene00007983
• Length: 548
• Species: Caenorhabditis elegans
• Alignment Length: 730
• Identity: 142/730 - (19%)
• Similarity: 275/730 - (37%)
• Gaps: 206/730 - (28%)

  Fly   615 SRQSMSPERTQRDVTESCEDVTERTEMESSMSHRNSEEDL------SPHAKRFKDEGQNGFEELR 673
            ||.|    :.:|.::.|.      .::.||:|.:||...|      |......|....:.|.:||
 Worm     3 SRMS----KLRRSISRSV------FQLNSSLSRQNSLNGLVDLPTMSNTTLVDKFATPSNFRQLR 57

  Fly   674 RYVKQGGDFSKELIFVLQERADSELIYSKSLSKLANKLNKAGREIPGSVADAWRGVATEMESRSD 738
            ..::...:...|::...:|:|..:..|||:|.|::.:|:|..:.:...:...|..||.:.:..:.
 Worm    58 DLIRNNNELLAEVVTAFEEKAALDFHYSKTLKKISIRLHKLTQSVESGIDKGWTNVAEQFDIHAT 122

  Fly   739 IHRQLAASLTDELVKPLKIVVEGHHKARKAVESNVDKAARVLGEWRASEAKAKKASHTAARENEK 803
            ||..|.:::|:::::||:.:.....|..:|.::.|::..|.|.:.:....|.|::.:..|:|.||
 Worm   123 IHSNLGSAITEDIIQPLRSIQSNQQKTIRAADNFVEREIRKLKDKKDETQKMKRSLYVLAKELEK 187

  Fly   804 LQDAMLDVRIQKSPSIALLHQGPNKQAAEKELKSAEKDCVKLDNKRKKAEEAVKRADVEYYTLCV 868
            .::                       :||:|....||..:    :|||.::.:.|::.:|....|
 Worm   188 TEN-----------------------SAEREKAQPEKFAL----RRKKYKDQMIRSEDDYVWQTV 225

  Fly   869 RSERARVDWEMAVLRGSAQLQSSEQQRLGNMHNFAQQYARLISDMNPILGGLSTRLQPQLDACNV 933
            ..|:.|...|..:.:|...::|.|:|||.:......:|.|.|..:.|.|..:..|....|:....
 Worm   226 DLEKQRRMTENVLRKGVESMESVERQRLAHCQTALGRYKRKIETLGPNLRQMFERHSNNLELAVD 290

  Fly   934 AKDMQVVRHIRRNSEGPSEQLLPDFYCEHTTLAMNRERRKHALIKLLQLVKTDLER--ERRSRDG 996
            :.....::.|:.::...:...|.|.:.|:....|:..||:..|.::..::.::|:|  ..::.|.
 Worm   291 SVPEDYIQTIQPSTSAVNHITLIDLHAENFGEVMSSTRRRQNLERVSGVLDSELKRLYNNQTADV 355

  Fly   997 LRGLSQSLNHQEHQNITDKLYHIRSMLTYLEGARLKLHSALLELD-HKPRATHPLAQHIHITRDR 1060
            :...|:.:                |:|.::|....||:.::..:| .:.|..|.|::..|..:|:
 Worm   356 MVSNSKQI----------------SVLEFIEYLYYKLNDSINIVDGGQNRGFHRLSRFQHKIKDK 404

  Fly  1061 TGLQQSILKVPNWLKNNDKSQTQQSTSMLAHDITDITTNHEDELPDENCSHLHSSSHSNNNSNGS 1125
            :||..:||.:|  |..::.|......||.|                       |:::.:...:|.
 Worm   405 SGLPMTILTIP--LSGDNNSLPPPCLSMEA-----------------------STAYPSPRGSGE 444

  Fly  1126 CTDVSSVVKPFNRSKSNIETNFTSQPKIISTTNAAIAVSVKSKTLANLQDGHHNNQQHHHHHHNH 1190
            ..:...:                |.....|||..:
 Worm   445 YEEYEKI----------------SDDGFYSTTTTS------------------------------ 463

  Fly  1191 HSDRGQADGGSNQQDSDFDEFSSQDEDDEPQQPQQQPQPLQSQQQQQQPLLQNPTINGQVQTQHF 1255
                  ::||..:..:.|||            |...|                |||
 Worm   464 ------SNGGPIRTTTTFDE------------PTSSP----------------PTI--------- 485

  Fly  1256 YQNAQELQKGQKNGSVPILGRCKALYSYTPKLYDELELSPGDIIEVHAKQDDGWWLG-ALRNH-- 1317
                                 |:.||.:.||..||:|:..|..:.|..:..|.|.:| .:..|
 Worm   486 ---------------------CRVLYDFEPKHADEIEIREGQCVLVEDRIGDDWLIGHVISQHDN 529

  Fly  1318 ------IGIFPATYV 1326
                  .|.||.|||
 Worm   530 SSIDPRSGRFPTTYV 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nost	NP_001285029.1	F-BAR_NOSTRIN	663..908	CDD:153342	54/244 (22%)
		SH3_Nostrin	1276..1328	CDD:212757	20/60 (33%)
C36E8.4	NP_497805.2	BAR	47..265	CDD:299863	54/244 (22%)
		SH3	485..543	CDD:212690	18/87 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	78	1.000	Domainoid score	I5690
eggNOG	1	0.900	-	-		E1_KOG4429
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006524
OrthoInspector	1	1.000	-	-		oto20204
orthoMCL	1	0.900	-	-		OOG6_108098
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4981
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.700