Protein Alignment Nost and nostrin

DIOPT Version :10

• Sequence 1: NP_001285029.1
• Gene: Nost / 8673992
• FlyBaseID: FBgn0259734
• Length: 1330
• Species: Drosophila melanogaster
• Sequence 2: NP_001107076.2
• Gene: nostrin / 100148449
• ZFINID: ZDB-GENE-070522-2
• Length: 537
• Species: Danio rerio
• Alignment Length: 670
• Identity: 161/670 - (24%)
• Similarity: 281/670 - (41%)
• Gaps: 168/670 - (25%)

  Fly   669 FEELRRYVKQGGDFSKELIFVLQERADSELIYSKSLSKLANKLNKAGREI-PGSVADAWRGVATE 732
            ::||:|..|.|..|.|||:.|.|:|::.|:.|||.|.|:|.||.|..:|: ..|...||..::.|
Zfish    14 YQELKRISKNGEFFCKELLAVFQQRSELEINYSKGLQKIAGKLLKVSKEMSDNSTYHAWSFISDE 78

  Fly   733 MESRSDIHRQLAASLTDELVKPLKIVVEGHHKARKAVESNVDKAAR-VLGEWRASEAKAKKASHT 796
            |.:.:|.||.|..:|..::::.::.:::.|.|.::.:::.|:|:.: ||..| :.:.|.||....
Zfish    79 MFASADAHRILGNALNQDVIQEIRQILDEHGKRKRPLDNAVEKSGKLVLTNW-SEQIKLKKKLIG 142

  Fly   797 AARENEKLQDAMLDVRIQKSPSIALLHQGPNKQAAEKELKSAEKDCVKLDNKRKKAEEAVKRADV 861
            ..||:|.|...     ::|           |||..      .||:..|:.|:..|:.|...|.|.
Zfish   143 LTREHEALFSF-----VEK-----------NKQIC------TEKEKQKMFNRLSKSAELQVRVDE 185

  Fly   862 EYYTLCVRSERARVDWEMAVLRGSAQLQSSEQQRLGNMHNFAQQYARLISDMNPILGGLSTRLQP 926
            ||:...:.....|:..|..:......:|..|:||:..:.|...:|:..::..:..:.....::..
Zfish   186 EYFNTNMEGHHIRLKLENTLKTCYQIVQELEKQRIETLANTLNKYSLFMTVYSQTVIHSHKQIDQ 250

  Fly   927 QLDACNVAKDMQ-VVRHIRRNS-EGPSEQLLPDFYCEHTTLAMNRERRKHALIKLLQLVKTDLER 989
            .:...:|.||:| :|..:...: |..:|.|:.|::.|.....|.::|||.|:...||.::..:.:
Zfish   251 AVRRVDVEKDIQSLVEDVATTADENKAEFLMADYFEEEGKTMMGKDRRKDAIRTKLQRLEDWITK 315

  Fly   990 ERRSRDGLRGL----SQSLNHQEHQNI--TDKLYHIRSMLTYLEGARLKLHSALLELDHKPRATH 1048
            .:..|:||..:    ::..|....:|:  |::|         ||.|.|||.  |||..| .:.||
Zfish   316 SKTDREGLEKMVKVYTEQPNFSNQKNLEETEQL---------LEEAILKLD--LLEATH-CKLTH 368

  Fly  1049 PLAQHIHITRDRTGLQQSILKVPNWLKNNDKSQTQQSTSMLAHDITDITTNHEDELPDENCSHLH 1113
            .||:                     ::...||:         |..:|..|..:    :::|.|
Zfish   369 SLAE---------------------IEGKPKSR---------HRFSDSITKWK----EKDCEH-- 397

  Fly  1114 SSSHSNNNSNGSCTDVSSVVKPFNRSKSNIETNFTSQPKIISTTNAAIAVSVKSKTLANLQDGHH 1178
                          .|..:.:|....|    |.|.|:..:.:|.:
Zfish   398 --------------SVVQLSRPVRIKK----TPFRSRQSMRATVS-------------------- 424

  Fly  1179 NNQQHHHHHHNHHSDRGQADGGSNQQDSDFDEFSSQDEDDEPQQPQQQPQPLQSQQQQQQPLLQN 1243
                      |..|...:..|     ::..:|.::.|..                        :|
Zfish   425 ----------NETSPSPEGTG-----ENPLNEATNSDGQ------------------------KN 450

  Fly  1244 PTINGQVQTQHFYQNAQELQKGQKNGSVPILGRCKALYSYTPKLYDELELSPGDIIEVHAKQDDG 1308
            ..:||.|..   |::       .|...:..:||||||||:.....|||.::.||::|:..|.|.|
Zfish   451 GPVNGSVSE---YED-------DKGAELCCIGRCKALYSFASDREDELNINEGDVLEIFEKDDTG 505

  Fly  1309 WWLGALRNHIGIFPATYVEE 1328
            ||.|.|....|:||:|||||
Zfish   506 WWFGELNGQRGLFPSTYVEE 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nost	NP_001285029.1	F-BAR_NOSTRIN	663..908	CDD:153342	69/240 (29%)
		SH3_Nostrin	1276..1328	CDD:212757	26/51 (51%)
nostrin	NP_001107076.2	None