DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nost and sh3d21

DIOPT Version :9

Sequence 1:	NP_001285029.1	Gene:	Nost / 8673992	FlyBaseID:	FBgn0259734	Length:	1330	Species:	Drosophila melanogaster
Sequence 2:	XP_004911622.2	Gene:	sh3d21 / 100145355	XenbaseID:	XB-GENE-5889544	Length:	552	Species:	Xenopus tropicalis

Alignment Length:	179	Identity:	40/179 - (22%)
Similarity:	76/179 - (42%)	Gaps:	27/179 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly  1152 KIISTTNAAIAVSVKSKTLANLQDGHHNNQQHHHHHHNHHSDRGQADGGSNQQDSDFDEFSSQDE 1216
            |..|.....::|....:.|..::||....:            :|:|.|.          |.|...
Frog   120 KASSADELELSVGEVFQVLEEIEDGWWLGK------------KGEAVGA----------FPSNFV 162

  Fly  1217 DDEPQQPQQQPQPLQSQQQQQQPLLQNPTINGQVQTQHFYQNAQELQKGQKNGSVPILGR--CKA 1279
            .:.|:.|.:: .|..|:..:::|.:.:...:.:.:.:...::....:...|..|.|...:  |:.
Frog   163 KEVPEPPSEK-IPELSKNAKKRPAMMDINFSAKEEEKSKQEDKSVPENQSKEDSSPPHAKEYCRV 226

  Fly  1280 LYSYTPKLYDELELSPGDIIEVHAKQ--DDGWWLGALRNHIGIFPATYV 1326
            ::.|.|.|.|||.|..||:|.:.:|:  |:|||.|......|:||..:|
Frog   227 MFDYKPFLPDELALKKGDVILLISKETGDEGWWQGEHNGKTGLFPDNFV 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nost	NP_001285029.1	F-BAR_NOSTRIN	663..908	CDD:153342
Nost	NP_001285029.1	SH3_Nostrin	1276..1328	CDD:212757	21/55 (38%)
sh3d21	XP_004911622.2	SH3	6..59	CDD:418401
		SH3_CD2AP-like_2	112..164	CDD:212807	11/65 (17%)
		SH3_D21-like	223..277	CDD:213018	21/53 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1577081at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010