Protein Alignment EIF3G and trv

DIOPT Version :10

• Sequence 1: NP_003746.2
• Gene: EIF3G / 8666
• HGNCID: 3274
• Length: 320
• Species: Homo sapiens
• Sequence 2: NP_001163754.3
• Gene: trv / 43362
• FlyBaseID: FBgn0085391
• Length: 651
• Species: Drosophila melanogaster
• Alignment Length: 304
• Identity: 72/304 - (23%)
• Similarity: 105/304 - (34%)
• Gaps: 108/304 - (35%)

Human    41 TSPEPELLPGAPLPPPKEV-INGNIKTVTEYKIDED-------GKKFKIV---RTFRIETRKASK 94
            |.|.|..|   |||||... ..|..:.:.:  .||:       .|:|.|.   .:..|||::..:
  Fly   271 TPPAPHSL---PLPPPHAARTEGGGQDMED--SDEEMEYMPPLHKQFHIFVGDLSSEIETQQLRE 330

Human    95 AVARRKNWKKFGNSEFDPPGPNVATTTVSDDVSM--------TFITSKEDLNCQEEEDPMNKLKG 151
            |              |.|.|.......|.|..::        :||..      .|.|..:..:.|
  Fly   331 A--------------FTPFGEISDCRVVRDPQTLKSKGYGFVSFIKK------SEAESAITAMNG 375

Human   152 QKIVSCRICKGDHWTTRCPYKDTLGPMQKELAEQLGLSTGEKEKLPGELEPVQATQNKTGKYVPP 216
            |.:.|..|  ..:|.||.|      |..||                 .::|:...:    .|
  Fly   376 QWLGSRSI--RTNWATRKP------PASKE-----------------NIKPLTFDE----VY--- 408

Human   217 SLRDGASRRGESMQPNRRADDNATIRV-------TNLSEDTRETDLQELFRPFGSISRIYLAKDK 274
                           |:.:..|.|:.|       |.|||:.    ||:.|.|:|:|..|.:.||
  Fly   409 ---------------NQSSPSNCTVYVGGVNSALTALSEEV----LQKTFAPYGAIQEIRVFKD- 453

Human   275 TTGQSKGFAFISFHRREDAARAIAGVSGFGYDHLILNVEWAKPS 318
                 ||:||:.|..:|.|..||.||.....:...:...|.|.|
  Fly   454 -----KGYAFVRFSTKEAATHAIVGVHNTEINAQPVKCSWGKES 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EIF3G	NP_003746.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..59		9/17 (53%)
		eIF3G	62..173	CDD:240597	27/128 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	209..234		2/24 (8%)
		RRM_eIF3G_like	240..315	CDD:409842	26/81 (32%)
trv	NP_001163754.3	RRM2_TIA1_like	313..387	CDD:409789	18/95 (19%)
		RRM3_TIA1_like	416..489	CDD:409790	26/82 (32%)