Protein Alignment EIF3G and eIF3g1

DIOPT Version :10

• Sequence 1: NP_003746.2
• Gene: EIF3G / 8666
• HGNCID: 3274
• Length: 320
• Species: Homo sapiens
• Sequence 2: NP_570011.1
• Gene: eIF3g1 / 31243
• FlyBaseID: FBgn0029629
• Length: 269
• Species: Drosophila melanogaster
• Alignment Length: 313
• Identity: 130/313 - (41%)
• Similarity: 171/313 - (54%)
• Gaps: 52/313 - (16%)

Human     9 KPSWADQVEEEGEDDKCVTSELLKGIPLATGDTSPEPELLPGAPLPPPKEVINGNIKTVTEYKID 73
            |.||||:||                              |....|||..|.:....|.|||||.:
  Fly     8 KSSWADEVE------------------------------LDYGGLPPTTETVENGQKYVTEYKYN 42

Human    74 EDGKKFKIVRTFRIETRKASKAVARRKNWKKFGNSEFDPPGPNVATTTVSDDVSMTFITSKEDLN 138
            :|.||.|:|||::|..:...|.||:|:.|.|||:|:.|.||||..||.||:::.|.|:.||||
  Fly    43 KDDKKTKVVRTYKISKQVVPKTVAKRRTWTKFGDSKNDKPGPNSQTTMVSEEIIMQFLNSKED-- 105

Human   139 CQEEEDPMNKLKGQK-IVSCRICKGDHWTTRCPYKDTLGPMQKELAEQLGLSTGEKEKLPGELEP 202
             ::..||:  |...| |..||||.|:||:..||||.|            .:.|...||.......
  Fly   106 -EKANDPL--LDPTKNIAKCRICNGEHWSVNCPYKGT------------AMDTNMMEKKASAAAA 155

Human   203 VQATQNKTGKYVPPSLRDGASRRGESMQPNRRADDNATIRVTNLSEDTRETDLQELFRPFGSISR 267
            ......|:||||||.|:|  |::|......|  ||.|.||::||||...|.||:||.:..|..|:
  Fly   156 AAVDAPKSGKYVPPFLKD--SQKGALGMRGR--DDTAAIRISNLSESMTEADLEELVKKIGPQSK 216

Human   268 IYLAKDKTTGQSKGFAFISFHRREDAARAIAGVSGFGYDHLILNVEWAKPSTN 320
            :|||:||.||..||||::.|.:|:|||.||..::|.|||||||:|||:||..|
  Fly   217 MYLARDKNTGLCKGFAYVHFKQRKDAAAAIEILNGHGYDHLILSVEWSKPQNN 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EIF3G	NP_003746.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..59		11/49 (22%)
		eIF3G	62..173	CDD:240597	53/111 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	209..234		11/24 (46%)
		RRM_eIF3G_like	240..315	CDD:409842	41/74 (55%)
eIF3g1	NP_570011.1	eIF3g	23..140	CDD:463545	58/133 (44%)
		RRM_eIF3G_like	190..264	CDD:409842	41/73 (56%)