| Sequence 1: | NP_001032360.1 | Gene: | EIF3B / 8662 | HGNCID: | 3280 | Length: | 814 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_611228.1 | Gene: | eIF3b / 36981 | FlyBaseID: | FBgn0034237 | Length: | 690 | Species: | Drosophila melanogaster |
| Alignment Length: | 702 | Identity: | 354/702 - (50%) |
|---|---|---|---|
| Similarity: | 478/702 - (68%) | Gaps: | 32/702 - (4%) |
- Green bases have known domain annotations that are detailed below.
|
Human 121 AQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGIDS 185
Human 186 VIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYP-EEDGKTKGYIFLEYASPAHAVDAVKN 249
Human 250 ADGYKLDKQHTFRVNLFTDFDKYMTISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGD 314
Human 315 RTSI--FWNDV-KDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALWGGEKFKQIQRFSHQGV 376
Human 377 QLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFHCESSAHWPIFKWSHDGKFFARM 441
Human 442 TLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGNIIAFWVPEDKDIPARVTLMQLPTRQEIRV 506
Human 507 RNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQ----------GVVTNFEIFRMREKQVPVDVVEM 561
Human 562 KETIIAFAWEPNGSKFAVLHGEAPRISVSFYHVKNNGKIELIKMFDKQQANTIFWSPQGQFVVLA 626
Human 627 GLRSMNGALAFVD-TSDCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRL 690
Human 691 LQKNNKDRFCQLLWRPRPPTLLSQEQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMME 755
Human 756 DFRKYRKMAQELYMEQKNERLELRGGVDTDELDSNVDDWEEETIEFFVTEEI 807 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| EIF3B | NP_001032360.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..158 | 9/36 (25%) | |
| PRK07764 | <4..161 | CDD:236090 | 10/39 (26%) | ||
| Sufficient for interaction with EIF3E | 124..413 | 139/292 (48%) | |||
| Sufficient for interaction with EIF3J | 170..274 | 63/104 (61%) | |||
| RRM_eIF3B | 184..264 | CDD:409720 | 45/80 (56%) | ||
| COG5354 | 305..805 | CDD:227657 | 265/513 (52%) | ||
| WD40 repeat | 338..371 | CDD:293791 | 19/32 (59%) | ||
| WD 3 | 366..425 | 28/58 (48%) | |||
| WD40 repeat | 376..423 | CDD:293791 | 23/46 (50%) | ||
| WD 4 | 426..489 | 36/62 (58%) | |||
| WD40 repeat | 429..463 | CDD:293791 | 21/33 (64%) | ||
| WD40 repeat | 467..506 | CDD:293791 | 23/38 (61%) | ||
| WD 5 | 490..553 | 43/72 (60%) | |||
| WD40 repeat | 514..545 | CDD:293791 | 21/40 (53%) | ||
| WD 6 | 554..598 | 24/43 (56%) | |||
| WD40 repeat | 556..604 | CDD:293791 | 25/47 (53%) | ||
| WD 7 | 599..642 | 19/43 (44%) | |||
| WD40 repeat | 612..647 | CDD:293791 | 16/35 (46%) | ||
| WD 8 | 643..685 | 20/41 (49%) | |||
| WD40 repeat | 654..684 | CDD:293791 | 19/29 (66%) | ||
| eIF3b | NP_611228.1 | WD40 | <216..352 | CDD:295369 | 75/139 (54%) |
| WD40 repeat | 216..248 | CDD:293791 | 18/31 (58%) | ||
| WD40 repeat | 297..321 | CDD:293791 | 10/23 (43%) | ||
| RRM_eIF3B | 56..137 | CDD:240724 | 45/80 (56%) | ||
| COG5354 | 194..690 | CDD:227657 | 263/501 (52%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165156354 | |
| Domainoid | 1 | 1.000 | 258 | 1.000 | Domainoid score | I2021 |
| eggNOG | 1 | 0.900 | - | - | E1_COG5354 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H2780 | |
| Inparanoid | 1 | 1.050 | 703 | 1.000 | Inparanoid score | I669 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG54076 | |
| OrthoDB | 1 | 1.010 | - | - | D1194797at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0003562 | |
| OrthoInspector | 1 | 1.000 | - | - | oto89310 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_101924 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR14068 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R377 |
| SonicParanoid | 1 | 1.000 | - | - | X2436 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 16 | 15.800 | |||||