Protein Alignment ALDH4A1 and Aldh4a1

DIOPT Version :10

• Sequence 1: NP_003739.2
• Gene: ALDH4A1 / 8659
• HGNCID: 406
• Length: 563
• Species: Homo sapiens
• Sequence 2: NP_780647.3
• Gene: Aldh4a1 / 212647
• MGIID: 2443883
• Length: 562
• Species: Mus musculus
• Alignment Length: 562
• Identity: 516/562 - (91%)
• Similarity: 549/562 - (97%)
• Gaps: 0/562 - (0%)

Human     2 LLPAPALRRALLSRPWTGAGLRWKHTSSLKVANEPVLAFTQGSPERDALQKALKDLKGRMEAIPC 66
            :||.|:|||:|||..|.||||||||||||||.|||:|||:||||||||||||||||||:||||||
Mouse     1 MLPLPSLRRSLLSHAWRGAGLRWKHTSSLKVTNEPILAFSQGSPERDALQKALKDLKGQMEAIPC 65

Human    67 VVGDEEVWTSDVQYQVSPFNHGHKVAKFCYADKSLLNKAIEAALAARKEWDLKPIADRAQIFLKA 131
            |||||||||||:|||:|||||.|||||||||||:|||:||:|||||||||||||:|||||:||||
Mouse    66 VVGDEEVWTSDIQYQLSPFNHAHKVAKFCYADKALLNRAIDAALAARKEWDLKPMADRAQVFLKA 130

Human   132 ADMLSGPRRAEILAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISVPPSTNSTV 196
            |||||||||||:||||||||||||||||||||||||||||||||:||||||:||||||||||.||
Mouse   131 ADMLSGPRRAEVLAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPSTNHTV 195

Human   197 YRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQF 261
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   196 YRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQF 260

Human   262 VPADGPLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKNFHFVHRS 326
            ||||||.|||||||||||||||||||||||||||:|||||||||.||||||||||||||||||.|
Mouse   261 VPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAGECGGKNFHFVHSS 325

Human   327 ADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSRIKVGDPAEDFGTFFSAV 391
            |||:|||||||||||||||||||||||||||.|||||||||||||||||||||||||||||||||
Mouse   326 ADVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLLEEHSRIKVGDPAEDFGTFFSAV 390

Human   392 IDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIVESKDPQEPIMKEEIFGPVLSVY 456
            ||||:|||||||||||||||||:|||||:|::||||:|||||:|||||||||||||||||||:||
Mouse   391 IDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIESKDPQEPIMKEEIFGPVLTVY 455

Human   457 VYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEATKVLRNAAGNFYINDKSTGSIVGQQPFG 521
            |||||||:|||||||||||||||||||:|||.:|||||::|||||||||||||||||:|||||||
Mouse   456 VYPDDKYRETLQLVDSTTSYGLTGAVFAQDKAIVQEATRMLRNAAGNFYINDKSTGSVVGQQPFG 520

Human   522 GARASGTNDKPGGPHYILRWTSPQVIKETHKPLGDWSYAYMQ 563
            ||||||||||||||||||||||||||||||||||||.|:|||
Mouse   521 GARASGTNDKPGGPHYILRWTSPQVIKETHKPLGDWRYSYMQ 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ALDH4A1	NP_003739.2	ALDH_F4-17_P5CDH	32..553	CDD:143441	483/520 (93%)
Aldh4a1	NP_780647.3	ALDH_F4-17_P5CDH	31..552	CDD:143441	483/520 (93%)