Protein Alignment DDX3Y and ddx3xa

DIOPT Version :10

• Sequence 1: NP_004651.2
• Gene: DDX3Y / 8653
• HGNCID: 2699
• Length: 660
• Species: Homo sapiens
• Sequence 2: XP_021334401.1
• Gene: ddx3xa / 566947
• ZFINID: ZDB-GENE-030131-1565
• Length: 841
• Species: Danio rerio
• Alignment Length: 868
• Identity: 510/868 - (58%)
• Similarity: 567/868 - (65%)
• Gaps: 235/868 - (27%)

Human     1 MSHVVVKNDPELDQQLANLDLNSEKQSGGASTASKGRYIPPHLRNREASK--------------- 50
            ||||||.....||||||.|||||   :.|....:..|||||||||::|||
Zfish     1 MSHVVVDGSHGLDQQLAVLDLNS---ADGQGVGTGRRYIPPHLRNKDASKNAGNAYSSGRQSGYS 62

Human    51 ----------------------------------------------------------------- 50
                                                                             
Zfish    63 VAPVQSFSPKQYPQSWHPEGNQRHRQNYPTGWNDFRTGNYLEKADLLLRSSICEGMVVLSALYFC 127

Human    51 ----------------------------------------------------------------- 50
                                                                             
Zfish   128 LGSQRFASQELAFYHTYTSGWPDRCASPARTDSSVATDGNEDTASVISWADRCDSPGWDGSRTNG 192

Human    51 ---GFHD-----------------------------------------------KDSSGWSCSKD 65
               |:||                                               || .||:...:
Zfish   193 FVNGYHDSRMNGTANFARGPLRNDRGGRGGFRGNRNGASFNQPVHNAGYGTYENKD-GGWNSVVN 256

Human    66 KDAYSSFGSRDSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGRFERSGHSRWCDKS- 129
            :|||:|||.|..|||..:|::||:.||||:              ||.|||. ...|:|||.::|
Zfish   257 RDAYASFGGRSDRGKSAFFNDRGASSRGRY--------------ERGGFGG-GTGGNSRWVEESR 306

Human   130 VEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIE 194
            .|:|||||:||:||||.||||..||||||||||||||||||:|.|.|||:|.|:||||||||||.
Zfish   307 DEEDWSKPMPPNERLEHELFSASNTGINFEKYDDIPVEATGTNSPGHIESFHDVDMGEIIMGNIT 371

Human   195 LTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVK-----E 254
            |:||||||||||:||||||.|||||||||||||||||||||:|||||::||||||:|.|     |
Zfish   372 LSRYTRPTPVQKYAIPIIKTKRDLMACAQTGSGKTAAFLLPVLSQIYSEGPGEALQATKASTQQE 436

Human   255 NGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLV 319
            ||:|.||||||||||||||||||:|||:|||||:|||||||||||||||||||||||||||||||
Zfish   437 NGKYVRRKQYPISLVLAPTRELALQIYDEARKFAYRSRVRPCVVYGGADIGQQIRDLERGCHLLV 501

Human   320 ATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFP 384
            ||||||||||||||||||:||||||||||||||||||||||||||||||||||.|.|||||||||
Zfish   502 ATPGRLVDMMERGKIGLDYCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGSRQTMMFSATFP 566

Human   385 KEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETK 449
            ||||:||||||:|||||||||||||||||||||||||:.||||||||:|.|||.|||||||||||
Zfish   567 KEIQILARDFLEEYIFLAVGRVGSTSENITQKVVWVEENDKRSFLLDLLNATGKDSLTLVFVETK 631

Human   450 KGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINF 514
            ||||:||||||.|||||||||||||||||||||||||||:.||:|||||||||||||||:|||||
Zfish   632 KGADALEDFLYREGYACTSIHGDRSQRDREEALHQFRSGRCPIMVATAVAARGLDISNVKHVINF 696

Human   515 DLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYK 579
            ||||||||||||||||||||||||||||:|:||.||||||||:||||||||||||||:||||.:|
Zfish   697 DLPSDIEEYVHRIGRTGRVGNLGLATSFYNDKNSNITKDLLDILVEAKQEVPSWLENLAYEHQHK 761

Human   580 GGSRGRSKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGG--GGYGGFYN 642
            ..:|||.|  |||||||||||||..|..:: || :||:.:.   ||:|.:|||||  ||:|.| .
Zfish   762 STNRGRPK--RFSGGFGARDYRQMPGGGNT-FG-NRGARNT---GGHGGNRGFGGNKGGFGSF-G 818

Human   643 SDGYGGNYNSQG-----VDWWGN 660
            .|.|||.|.:.|     ||||||
Zfish   819 GDSYGGTYGNYGGNYTQVDWWGN 841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DDX3Y	NP_004651.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..121		59/314 (19%)
		DEADc_DDX3	158..408	CDD:350809	224/254 (88%)
		Q motif	178..206		22/27 (81%)
		DEAD box	345..348		2/2 (100%)
		SF2_C_DEAD	413..543	CDD:350174	118/129 (91%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	578..625		23/46 (50%)
ddx3xa	XP_021334401.1	DEADc_DDX3	335..590	CDD:350809	224/254 (88%)
		SF2_C_DEAD	595..725	CDD:350174	118/129 (91%)