Protein Alignment DDX3Y and bel

DIOPT Version :10

• Sequence 1: NP_004651.2
• Gene: DDX3Y / 8653
• HGNCID: 2699
• Length: 660
• Species: Homo sapiens
• Sequence 2: NP_001262379.1
• Gene: bel / 45826
• FlyBaseID: FBgn0263231
• Length: 801
• Species: Drosophila melanogaster
• Alignment Length: 807
• Identity: 409/807 - (50%)
• Similarity: 494/807 - (61%)
• Gaps: 157/807 - (19%)

Human     1 MSHVVVKNDPELDQQLANLDLN--SEKQSG------GASTASKGRYIPPHLRNREASKGFHDKDS 57
            ||:.:.:|...|:||:|.||||  |...||      ..::.:.|.|:|||||....:....|.:|
  Fly     1 MSNAINQNGTGLEQQVAGLDLNGGSADYSGPITSKTSTNSVTGGVYVPPHLRGGGGNNNAADAES 65

Human    58 SGWSCSKDKDAYSSFG-----SRD---SRGKPGYFSERGSGSRGRFDDRGRSDY---DGIGNRER 111
            .|....:.:...|..|     :||   |||..|.: .||.|..||..:|...||   .|.|.| |
  Fly    66 QGQGQGQGQGFDSRSGNPRQETRDPQQSRGGGGEY-RRGGGGGGRGFNRQSGDYGYGSGGGGR-R 128

Human   112 PGFGRFE-----------------RSG----------------------HSRWCDKSVEDD---- 133
            .|.||||                 |||                      .|...:::.||.
  Fly   129 GGGGRFEDNYNGGEFDSRRGGDWNRSGGGGGGGRGFGRGPSYRGGGGGSGSNLNEQTAEDGQAQQ 193

Human   134 --------WSKPLPPS------------------------------------------------- 141
                    |.:|..|:
  Fly   194 QQQPRNDRWQEPERPAGFDGSEGGQSAGGNRSYNNRGERGGGGYNSRWKEGGGSNVDYTKLGARD 258

Human   142 ERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQK 206
            ||||.|||..|||||||:||:||||||||.|.||:|.:|.|:.:.|||..|:.|.||.:||||||
  Fly   259 ERLEVELFGVGNTGINFDKYEDIPVEATGQNVPPNITSFDDVQLTEIIRNNVALARYDKPTPVQK 323

Human   207 HAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDG---PGEALKAVKENGRYGRRKQYPISL 268
            ||||||...||||||||||||||||||:|||:|:|..|   |.::.:      :|.||||||:.|
  Fly   324 HAIPIIINGRDLMACAQTGSGKTAAFLVPILNQMYELGHVPPPQSTR------QYSRRKQYPLGL 382

Human   269 VLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK 333
            |||||||||.||:|||:||:||||:||.|:|||.:..:|:|:|:|||||:|||||||.||:.|||
  Fly   383 VLAPTRELATQIFEEAKKFAYRSRMRPAVLYGGNNTSEQMRELDRGCHLIVATPGRLEDMITRGK 447

Human   334 IGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEY 398
            :||:..::||||||||||||||||||||||||..|||.|.|.|:||||||||:||.||.|||..|
  Fly   448 VGLENIRFLVLDEADRMLDMGFEPQIRRIVEQLNMPPTGQRQTLMFSATFPKQIQELASDFLSNY 512

Human   399 IFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGAT------GSDSLTLVFVETKKGADSLED 457
            |||||||||||||||||.::||.:.||||:|||:|.:.      ..|||||:||||||||||||:
  Fly   513 IFLAVGRVGSTSENITQTILWVYEPDKRSYLLDLLSSIRDGPEYTKDSLTLIFVETKKGADSLEE 577

Human   458 FLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEE 522
            |||...:..|||||||:|::|||||..||||..|||||||||||||||.:|:||||||||||:||
  Fly   578 FLYQCNHPVTSIHGDRTQKEREEALRCFRSGDCPILVATAVAARGLDIPHVKHVINFDLPSDVEE 642

Human   523 YVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSR-GRS 586
            ||||||||||:||||:|||||||||.||..|||:||:|.|||:||::|:|:.:..:.|..| ||.
  Fly   643 YVHRIGRTGRMGNLGVATSFFNEKNRNICSDLLELLIETKQEIPSFMEDMSSDRGHGGAKRAGRG 707

Human   587 KSNRFSGGFGARDYRQSSGSSSSGFGA----SRGSSSRSGGGGY---GNSRG-----FGGGG-YG 638
            ...|:.||||:||||||||....|...    |.||.|..|||.|   |||.|     .|||| ||
  Fly   708 GGGRYGGGFGSRDYRQSSGGGGGGRSGPPPRSGGSGSGGGGGSYRSNGNSYGKFGGNSGGGGYYG 772

Human   639 GFYNSDGYGGNY-------NSQGVDWW 658
            |......|||:|       :|...|||
  Fly   773 GGAGGGSYGGSYGGGSASHSSNAPDWW 799

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DDX3Y	NP_004651.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..121		50/155 (32%)
		DEADc_DDX3	158..408	CDD:350809	171/252 (68%)
		Q motif	178..206		13/27 (48%)
		DEAD box	345..348		2/2 (100%)
		SF2_C_DEAD	413..543	CDD:350174	95/135 (70%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	578..625		24/51 (47%)
bel	NP_001262379.1	DEADc_DDX3	275..522	CDD:350809	171/252 (68%)
		SF2_C_DEAD	527..663	CDD:350174	95/135 (70%)