Protein Alignment DDX3Y and ddx3x

DIOPT Version :10

• Sequence 1: NP_004651.2
• Gene: DDX3Y / 8653
• HGNCID: 2699
• Length: 660
• Species: Homo sapiens
• Sequence 2: XP_012812110.1
• Gene: ddx3x / 394804
• XenbaseID: XB-GENE-999731
• Length: 723
• Species: Xenopus tropicalis
• Alignment Length: 733
• Identity: 557/733 - (75%)
• Similarity: 603/733 - (82%)
• Gaps: 83/733 - (11%)

Human     1 MSHVVVKNDPELDQQLANLDLNS-EKQSGGASTASKGRYIPPHLRNREAS--------------- 49
            ||||.|:|...||||.|.||||| :.||||::|  |||||||||||:|||
 Frog     1 MSHVAVENVLSLDQQFAGLDLNSADAQSGGSAT--KGRYIPPHLRNKEASRQGYPRCQYPAVDVY 63

Human    50 -----------------------------------------------------KGFHDKDSSGWS 61
                                                                 :||:|:::|||:
 Frog    64 KGYGDWWSQRTDANWDAGRGGNGYVNGTNDDRDSRMNGYDRSGYGNRGSGRTDRGFYDRENSGWN 128

Human    62 CSKDKDAYSSFGSRDSRGKPGYFSER-GSGSRGRFDDRGRSDYDGIGNR-ERPGFGRFERSGHSR 124
            ..:|||||||||||..||||..|::| ||||| |.|||....|||:.|| :|.|||||:| |:||
 Frog   129 SGRDKDAYSSFGSRGERGKPSLFNDRGGSGSR-RPDDRRPDGYDGMANRGDRSGFGRFDR-GNSR 191

Human   125 WCD-KSVEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEI 188
            |.| ::.||||||||.|::|:|||||||.||||||||||||||||||:|||||||:|.|:.||||
 Frog   192 WSDERNDEDDWSKPLAPNDRVEQELFSGSNTGINFEKYDDIPVEATGNNCPPHIESFQDVTMGEI 256

Human   189 IMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVK 253
            |||||:|:||||||||||||||||..|||||||||||||||||||||||||||.||||:|:|.:|
 Frog   257 IMGNIQLSRYTRPTPVQKHAIPIIIEKRDLMACAQTGSGKTAAFLLPILSQIYADGPGDAMKHLK 321

Human   254 ENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLL 318
            ||||||||||:|:|||||||||||||||||||||:||||||||||||||||||||||||||||||
 Frog   322 ENGRYGRRKQFPLSLVLAPTRELAVQIYEEARKFAYRSRVRPCVVYGGADIGQQIRDLERGCHLL 386

Human   319 VATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATF 383
            |||||||||||||||||||||.||||||||||||||||||||||||||||||||||.||||||||
 Frog   387 VATPGRLVDMMERGKIGLDFCNYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRQTMMFSATF 451

Human   384 PKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVET 448
            |||||:||||||||||||||||||||||||||||||||::||||||||:|.|||.||||||||||
 Frog   452 PKEIQILARDFLDEYIFLAVGRVGSTSENITQKVVWVEEMDKRSFLLDLLNATGKDSLTLVFVET 516

Human   449 KKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVIN 513
            |||||:||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||
 Frog   517 KKGADALEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVIN 581

Human   514 FDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHY 578
            ||||||||||||||||||||||||||||||||||:|||||||||||||||||||||||||||.|:
 Frog   582 FDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNINITKDLLDLLVEAKQEVPSWLENMAYEQHH 646

Human   579 KGGSRGRSKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGGGGYGGFYNS 643
            |..:|||||| ||||||||||||||||:||...|:|||..|    .|:|.|||| ||||||||||
 Frog   647 KSSTRGRSKS-RFSGGFGARDYRQSSGASSGFGGSSRGGRS----SGHGGSRGF-GGGYGGFYNS 705

Human   644 DGYGGNY-NSQGVDWWGN 660
            ||||||| .|..||||||
 Frog   706 DGYGGNYGGSSQVDWWGN 723

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DDX3Y	NP_004651.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..121		79/190 (42%)
		DEADc_DDX3	158..408	CDD:350809	229/249 (92%)
		Q motif	178..206		21/27 (78%)
		DEAD box	345..348		2/2 (100%)
		SF2_C_DEAD	413..543	CDD:350174	122/129 (95%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	578..625		30/46 (65%)
ddx3x	XP_012812110.1	PRK12678	<71..>167	CDD:237171	32/96 (33%)
		DEADc_DDX3	226..476	CDD:350809	229/249 (92%)
		SF2_C_DEAD	481..611	CDD:350174	122/129 (95%)