Protein Alignment DDX3Y and ddx3xb

DIOPT Version :10

• Sequence 1: NP_004651.2
• Gene: DDX3Y / 8653
• HGNCID: 2699
• Length: 660
• Species: Homo sapiens
• Sequence 2: XP_005168845.2
• Gene: ddx3xb / 30116
• ZFINID: ZDB-GENE-980526-150
• Length: 721
• Species: Danio rerio
• Alignment Length: 751
• Identity: 518/751 - (68%)
• Similarity: 570/751 - (75%)
• Gaps: 121/751 - (16%)

Human     1 MSHVVVKNDPELDQQLANLDLNSEKQSGGASTASKGRYIPPHLRNREASK--------------- 50
            ||||.|:|...||||||.|||:|....|    .:..|||||||||:||:|
Zfish     1 MSHVAVENVHGLDQQLAALDLSSADVQG----VTGRRYIPPHLRNKEAAKNDAPGGWDNGRSNGF 61

Human    51 --GFHD---------------------------------------------------KDSSGWSC 62
              |:||                                                   ||:.||:.
Zfish    62 VNGYHDGRDNRMNGGSSFAGRGPIRSDRGGRGGFRGKSTGSYNPIQPMQSAGFGYDNKDAGGWNV 126

Human    63 SKDKDAYSSFGSRDSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGRFERSGHSRWCD 127
            .|| :||:|||.|..|||..:|::|||.||||:              ||.|||   ..|:|||.:
Zfish   127 PKD-NAYNSFGGRSDRGKSSFFNDRGSSSRGRY--------------ERGGFG---GGGNSRWVE 173

Human   128 KSVEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGN 192
            :..::||||||||:||||.|||||.||||||||||||||||||.|.|..|::|.|::||||||||
Zfish   174 ECRDEDWSKPLPPNERLEHELFSGSNTGINFEKYDDIPVEATGHNGPQPIDSFHDLEMGEIIMGN 238

Human   193 IELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVK---- 253
            |.|:|||||||||||||||||.|||||||||||||||||||||:|||||||||||||:|.|
Zfish   239 INLSRYTRPTPVQKHAIPIIKSKRDLMACAQTGSGKTAAFLLPVLSQIYTDGPGEALQAAKNSAQ 303

Human   254 ENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLL 318
            |||:||||||||||||||||||||:|||:|||||||||.||||||||||||||||||||||||||
Zfish   304 ENGKYGRRKQYPISLVLAPTRELALQIYDEARKFSYRSHVRPCVVYGGADIGQQIRDLERGCHLL 368

Human   319 VATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATF 383
            |||||||||||||||||||:|.||||||||||||||||||||||||||||||||:|.||||||||
Zfish   369 VATPGRLVDMMERGKIGLDYCNYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGLRQTMMFSATF 433

Human   384 PKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGAT------------ 436
            |||||:||||||::||||||||||||||||||||||||:.||||||||:|.||
Zfish   434 PKEIQILARDFLEDYIFLAVGRVGSTSENITQKVVWVEENDKRSFLLDLLNATVIPSEVQESTGE 498

Human   437 -----GSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVAT 496
                 |.|||||||||||||||:||||||.|||||||||||||||||||||||||||:.||||||
Zfish   499 SVEKPGKDSLTLVFVETKKGADALEDFLYREGYACTSIHGDRSQRDREEALHQFRSGRCPILVAT 563

Human   497 AVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEA 561
            ||||||||||||:|||||||||||||||||||||||||||||||||||:||.||||||||:||||
Zfish   564 AVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNDKNGNITKDLLDILVEA 628

Human   562 KQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSSRSGGGGY 626
            |||||||||::||||.:|..||||||  |||||||||||||:|.|...|||...|.|:    ||:
Zfish   629 KQEVPSWLESLAYEHQHKSSSRGRSK--RFSGGFGARDYRQNSSSGGGGFGGRGGRST----GGH 687

Human   627 GNSRGFGG--GGYGGFYNSDGYGGNYNSQGVDWWGN 660
            |.:|||||  ||:|.||:||||||||:.  ||||||
Zfish   688 GGNRGFGGGKGGFGNFYSSDGYGGNYSQ--VDWWGN 721

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DDX3Y	NP_004651.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..121		60/187 (32%)
		DEADc_DDX3	158..408	CDD:350809	223/253 (88%)
		Q motif	178..206		20/27 (74%)
		DEAD box	345..348		2/2 (100%)
		SF2_C_DEAD	413..543	CDD:350174	119/146 (82%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	578..625		27/46 (59%)
ddx3xb	XP_005168845.2	None