DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment DDX3Y and Ddx3y

DIOPT Version :10

Sequence 1:NP_004651.2 Gene:DDX3Y / 8653 HGNCID:2699 Length:660 Species:Homo sapiens
Sequence 2:NP_036138.1 Gene:Ddx3y / 26900 MGIID:1349406 Length:658 Species:Mus musculus


Alignment Length:661 Identity:588/661 - (88%)
Similarity:621/661 - (93%) Gaps:4/661 - (0%)


- Green bases have known domain annotations that are detailed below.


Human     1 MSHVVVKNDPELDQQLANLDL-NSEKQSGGASTASKGRYIPPHLRNREASKGFHDKDSSGWSCSK 64
            ||.|..::...||||...||| :|:.|:||.:|.||||||||||||||.|||..|||||||||||
Mouse     1 MSQVAAESTAGLDQQFVGLDLKSSDNQNGGGNTESKGRYIPPHLRNRETSKGVCDKDSSGWSCSK 65

Human    65 DKDAYSSFGSRDSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGRFERSGHSRWCDKS 129
            |||||||||||||||||.|||:|||||||||||.||:||||||.|:|.|||:|||||||||.|:|
Mouse    66 DKDAYSSFGSRDSRGKPNYFSDRGSGSRGRFDDHGRNDYDGIGGRDRTGFGKFERSGHSRWSDRS 130

Human   130 VEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIE 194
            .||||||||||||||||||||||||||||||||||||||||:||||||||||||:||||||||||
Mouse   131 DEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIENFSDIEMGEIIMGNIE 195

Human   195 LTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYG 259
            |||||||||||||||||||.|||||||||||||||||||||||||||||||||||||:|||||||
Mouse   196 LTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAMKENGRYG 260

Human   260 RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGR 324
            ||||||||||||||||||||||||||||||||||||||||||||..|||||||||||||||||||
Mouse   261 RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADTVQQIRDLERGCHLLVATPGR 325

Human   325 LVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQM 389
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   326 LVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQM 390

Human   390 LARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADS 454
            ||||||||||||||||||||||||||||||||:|||||||||:|.|||.||||||||||||||||
Mouse   391 LARDFLDEYIFLAVGRVGSTSENITQKVVWVEELDKRSFLLDLLNATGKDSLTLVFVETKKGADS 455

Human   455 LEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSD 519
            ||:||:.|.||||||||||||:||||||||||||:.||||||||||||||||||:||||||||||
Mouse   456 LENFLFQERYACTSIHGDRSQKDREEALHQFRSGRKPILVATAVAARGLDISNVKHVINFDLPSD 520

Human   520 IEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRG 584
            ||||||||||||||||||||||||||:|:||||||||||||||||||||||:|||||||||.|||
Mouse   521 IEEYVHRIGRTGRVGNLGLATSFFNERNLNITKDLLDLLVEAKQEVPSWLESMAYEHHYKGSSRG 585

Human   585 RSKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGYGGN 649
            |||| |||||||||||||||||:::||.::|.:||||.|..:  :|||||||||||||:||||||
Mouse   586 RSKS-RFSGGFGARDYRQSSGSANAGFNSNRANSSRSSGSSH--NRGFGGGGYGGFYNNDGYGGN 647

Human   650 YNSQGVDWWGN 660
            ||||.||||||
Mouse   648 YNSQAVDWWGN 658

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DDX3YNP_004651.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..121 90/120 (75%)
DEADc_DDX3 158..408 CDD:350809 243/249 (98%)
Q motif 178..206 26/27 (96%)
DEAD box 345..348 2/2 (100%)
SF2_C_DEAD 413..543 CDD:350174 117/129 (91%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 578..625 35/46 (76%)
Ddx3yNP_036138.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..143 108/141 (77%)
DEADc_DDX3 159..409 CDD:350809 243/249 (98%)
Q motif 179..207 26/27 (96%)
DEAD box 346..349 2/2 (100%)
SF2_C_DEAD 414..544 CDD:350174 117/129 (91%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 597..627 18/31 (58%)

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