Protein Alignment DDX3Y and sum3

DIOPT Version :10

• Sequence 1: NP_004651.2
• Gene: DDX3Y / 8653
• HGNCID: 2699
• Length: 660
• Species: Homo sapiens
• Sequence 2: NP_588033.1
• Gene: sum3 / 2538689
• PomBaseID: SPCC1795.11
• Length: 636
• Species: Schizosaccharomyces pombe
• Alignment Length: 668
• Identity: 332/668 - (49%)
• Similarity: 424/668 - (63%)
• Gaps: 57/668 - (8%)

Human    12 LDQQLANLDLNSEK-QSGGASTASKGRYIPPHLRNRE---ASKGFHDKD---SSGWSCSKDKDAY 69
            :.||:.::...:|| |....|...|  ||||..|::.   |:....|.:   |.|.|.|:....:
pombe     5 VQQQVDSVGSVTEKLQKTNISRPRK--YIPPFARDKPSAGAAPAVGDDESVSSRGSSRSQTPSEF 67

Human    70 SS-FGSRDSRGKPGYFSERGSGSRGRFDDRGRSDY-DGIGNRERPGFGRFERSGHSRWCDKSVED 132
            || :|.|....:.|::. .|.|.:..:.......| :|.|.|...|||::....|......::
pombe    68 SSNYGGRREYNRGGHYG-GGEGRQNNYRGGREGGYSNGGGYRNNRGFGQWRDGQHVIGARNTL-- 129

Human   133 DWSKPLPPSERLEQELFSG------GNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMG 191
                       ||::||..      .:||||||||||||||.:|.:..| :..|:...:...::.
pombe   130 -----------LERQLFGAVADGTKVSTGINFEKYDDIPVEVSGGDIEP-VNEFTSPPLNSHLLQ 182

Human   192 NIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENG 256
            ||:|:.||:||||||::|||:...|||||||||||||||.||.||||..:..||. |:...::.|
pombe   183 NIKLSGYTQPTPVQKNSIPIVTSGRDLMACAQTGSGKTAGFLFPILSLAFDKGPA-AVPVDQDAG 246

Human   257 R-YGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVA 320
            . |..||.||.:|:|||||||..||:||:|||.|||.||||.|||||||..|||.:::||.||.|
pombe   247 MGYRPRKAYPTTLILAPTRELVCQIHEESRKFCYRSWVRPCAVYGGADIRAQIRQIDQGCDLLSA 311

Human   321 TPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPK 385
            |||||||:::||:|.|...|:|||||||||||||||||||.|||...|.....|.|:|||||||:
pombe   312 TPGRLVDLIDRGRISLANIKFLVLDEADRMLDMGFEPQIRHIVEGADMTSVEERQTLMFSATFPR 376

Human   386 EIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKK 450
            :||:||||||.:|:||:||||||||||||||||.|||.:|||:|||||.....:.|||:|||||:
pombe   377 DIQLLARDFLKDYVFLSVGRVGSTSENITQKVVHVEDSEKRSYLLDILHTLPPEGLTLIFVETKR 441

Human   451 GADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFD 515
            .||:|.|:|.:..:..|||||||:||:||.||..||||::.|:||||||:|||||.||.||||:|
pombe   442 MADTLTDYLLNSNFPATSIHGDRTQRERERALELFRSGRTSIMVATAVASRGLDIPNVTHVINYD 506

Human   516 LPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKG 580
            ||:||::||||||||||.||.|.|.:|||..|..|.|:|::||.||.||.||:|..||.|..:.|
pombe   507 LPTDIDDYVHRIGRTGRAGNTGQAVAFFNRNNKGIAKELIELLQEANQECPSFLIAMARESSFGG 571

Human   581 GSRGRSKSNRFSGG---FGARDYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGGGGYGGFYN 642
            ..||...|.|...|   :||||:|:.:.|||                  |.|.|....|||||.:
pombe   572 NGRGGRYSGRGGRGGNAYGARDFRRPTNSSS------------------GYSSGPSYSGYGGFES 618

Human   643 SDGYGGN-YNS-QGVDWW 658
            ...:.|| ||| ....||
pombe   619 RTPHHGNTYNSGSAQSWW 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DDX3Y	NP_004651.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..121		32/117 (27%)
		DEADc_DDX3	158..408	CDD:350809	153/250 (61%)
		Q motif	178..206		10/27 (37%)
		DEAD box	345..348		2/2 (100%)
		SF2_C_DEAD	413..543	CDD:350174	84/129 (65%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	578..625		14/49 (29%)
sum3	NP_588033.1	SrmB	171..550	CDD:440279	239/379 (63%)