|
Human 30 STEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTV-------------DQIQLMK 81
:.||||||.||.|:|:|:|:|:.|... |..|.||||..||.:.| |......
Fly 242 NNEKRRREAENGYIEQLSEILTLNKRG-DMTSTKPDKAAILNQVVRTYREICDKGQNRDISSTST 305
Human 82 RMEQEKSTTDDD-------------------------------VQKSDISSSSQGVIEKESLGPL 115
......:||::: ||:.::||:...:.| |.
Fly 306 NNNNSTTTTNNNTNSNNNNNTSKPQATSTRCSRCATDNCSIHPVQQGEVSSTEPPLPE-----PS 365
Human 116 LL-----------EALDGF-------FFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHV 162
|| |||:.: ...||..|.|...::|:...:||.::||.:..:|..|:.
Fly 366 LLLGQVPEISAYFEALEHYISGVGWVLLQVNANGIIESCTQNIRDLIGYEKQELYHQPLYMYLYS 430
Human 163 GDHA--EFVKNLL--------PKSLVNGVP-----------WPQ--------------------- 185
|||| |.:.|.: ..|..|..| |..
Fly 431 GDHAKLEPIINTMYNNPNGGNSNSANNSGPGGSSAGTSAGVWGDLEELNNGNASQGSNSSGAGGL 495
Human 186 ------EATRRNSHTFNCRMLIHPPDEPGTENQEACQ-----------RYEVMQCFTVSQPKSIQ 233
.|.::.|.:...|||: ......|:....|: :|| :...::.| ::
Fly 496 GGAGGAAAGKKRSISTKVRMLV-KDTRTATQTSSNCEEKPLRQSGHQDKYE--EVVLIAAP--VK 555
Human 234 EDGEDFQSCLICIARRLPRPPAITGVESFMTKQ---------DTTGKIISIDTSSLRA------- 282
:|.:...|.|..|.|.....|....::..:.:| |..|||:::|.::||.
Fly 556 DDADASSSVLCLITRPEDESPLEINIQQHVQQQPIEQMTFKLDIHGKILTLDPTALREPFKQHLQ 620
Human 283 --AGRTGWEDLVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSP---------SYRFILNDGT 336
.||. |:||... .:.|..:...:::....:|:|| |..|.|..|.
Fly 621 TWVGRL-WQDLCHP----------HDLSTLKSHLRDIQDSASANSPGAGAGTSVVSRPFRLRLGA 674
Human 337 M-LSAHTKC--KLCYPQSPDMQPFIMGIHIIDREHSGLSPQDDTNSGMSIPRVNPSVNPSISPAH 398
. :..|.|. :|...|:|....|||.:..: |:.::|.|| |...:.|...
Fly 675 PDVYVHVKANSRLFLNQTPGEGDFIMSVQTL------LNSENDMNS---------SNTGAGSGGL 724
Human 399 GVARSSTLPPSNSNMVSTRINRQQSSDLHSSSHSNSSNSQGSFGCSP---------GSQIVANVA 454
|:.:...:.||.| :.|:.::......||..:.|.||:|..:.|..| |.|
Fly 725 GLGQLCAMAPSPS-LASSLLSSLSMDGLHGGTGSGSSSSPAASGMLPTHLLGGLVGGGQ------ 782
Human 455 LNQGQASSQSSNPSLN---LNNSPMEGTGISLAQFMSPRRQVTSGLATRPRMPNNSFPP------ 510
||...:.:...|:. ::::.:.|||:...|....|...:|..::......|:|..
Fly 783 --QGGGGNSTQTTSVGGPLMSSAIINGTGLQQQQQQQQRSGASSSASSSANALVNAFTASPAPAE 845
Human 511 -----------NISTLSS-----PVGMTSSACNN--NNRSYSNIPVTSLQGMNEGPNNSVGFS-- 555
:|:..|| |.|...:..:: |:|:....||::.: |.:..|||
Fly 846 HSFYGSDTFEFDIAAHSSSFELDPSGGVGAWTDSRPNSRASVATPVSTPR-----PPSGHGFSPA 905
Human 556 -ASSPVLRQMSSQNSPSRLNIQPAKAES------------------KDNKEIASILNEMIQSDNS 601
.:||......|.:|.:.|....:.|.: |..|::....|:. ||:|:
Fly 906 VCASPATPYQLSSHSAASLPSPQSNASAGGGNYGGFNFHSFDSSDVKPEKDVQQQQNQQ-QSNNN 969
Human 602 SSDGKPLDSGLLHNNDRLSDGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLSCTGTSNS 666
||...||..|.|.| ..|....||...: |......:||.:..:.....:.:| |.:.
Fly 970 SSSSNPLLGGGLPN----GVGGMLLSQQQQQ--QQTPPQQQQQQQQQESSERLRHLL----TKSQ 1024
Human 667 ASANSSGGSCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPDKKDSASTSVSVTGQV------ 725
:.|...|| |.:..|... .||| :::..||....:.||.
Fly 1025 SMAGGLGG--------LGDDEKYFK---PEGS-----------EEEKHASGGFKMGGQPGGMGMF 1067
Human 726 ---------QGNSSIKLELDASKKKESKDHQLLRYLLDKDEKD--------------------LR 761
.||||: ..|...|::..||:.|.:|.|.| :|
Fly 1068 GPMGSMGRGVGNSSM-----LHKAGNSQNPMLLKLLNEKSEDDDGNGSGGGPGSMNNSRQSELMR 1127
Human 762 ----------------STPNLSLDDVKVKVEKKEQMDPCNTNPTPMTKPTPE---------EIKL 801
::.|:|.:|:|..: |.|.||.......:.:|..: ..||
Fly 1128 QLKNPDGGSHGMHRNSASGNMSTEDLKAML--KIQSDPSLNRKRSLNEPDDDPSAKRSEDKPSKL 1190
Human 802 EAQSQFTADLDQFDQLLPTL---EKAAQLPGLCETDRMDGAVTSVTIKSEI-LPASLQSA-TARP 861
..|::..|.|.|....:|.. |:..|:..|.: :||.|:.|.: .|.:|.|| :..|
Fly 1191 CTQNKMLAKLLQNPPKIPKAPNPEQPLQVKTLPD-------ITSSTVSSTLAAPGNLISAGSTGP 1248
Human 862 TSRLNRLPELELEAIDNQFGQPGTGDQIPWTNNTVTAI----NQSKSEDQCISSQLDELLCPP-- 920
.:..||..:.:.:....|..| ....|..| .|.:..|..:|.|..:.|..|
Fly 1249 KAAANRNRKQQQQQQQQQQQQ---------QQQQVAGIPSQQQQQQPNDVYLSQQQQQQLQSPQL 1304
Human 921 ------------TTVEGRNDEKALLEQLVSFLSGKDETELAELDRALGIDKLVQGGGLDVLSERF 973
|::.......|......:.| |:.::||::| ||.:.|.:
Fly 1305 AFQHQQLATTATTSITTAASTSAAAAAAAAIL-GEGDSELSKL--------------LDSVMEYY 1354
Human 974 PPQQATPPLIMEERP---------------NLYSQPYSSPSPTANLPSPFQGMVRQKPSLGTMPV 1023
|.. || |:...| ::.|..:.:......:.:..|...:|:.....:.:
Fly 1355 PDD--TP--IVTNAPSEASAINDIQKSLMLDVESAAFGNDLNQQLMMTQQQQHQQQQQQQQLLAL 1415
Human 1024 QVTPPRGAFSPGMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLIHQNRQAILNQFAATAPVGI 1088
|:...: ..|.:|.|.:|||.|..|.:|.||..|.|| ||:|.|:.:..|....|
Fly 1416 QLAQQQ-------QQQRQQHLQQPPAYPGMLNMQQQQHQQQQQ----QNQQHIMQRLEAMRNQG- 1468
Human 1089 NMRSGMQQQITPQP--------PLNA------------QML--AQRQRELYSQQHRQRQLIQQQR 1131
..|.|: |.| |:|| |.| .::|::|.:.|.::|.|.|||:
Fly 1469 --NQGFQR---PPPMYPARGRGPMNAVATPGGVVLPAQQQLRNIRQQQQLAAAQQKERLLQQQQK 1528
Human 1132 AMLM----RQQSFGN--------------------------NLPPSSGLP-VQMGNPRLPQGA-- 1163
..|: ..:.:|| :|..::|.| |.:....||..|
Fly 1529 QQLLVPENASEYWGNSNLQLIIKLIVSYILAGMNAGLNNIGSLLNTTGAPNVSLSRTNLPSDAQL 1593
Human 1164 ---------PQQF------PY--PPNYGTNPGTP-------PASTSPFSQLAAN--PEASLANRN 1202
.||. || .||.|..|..| |......||...| .:..||.:.
Fly 1594 SPNFAQTLMQQQLSPGRSAPYSPQPNQGYAPQFPQPGQRLSPQQQQQLSQQQQNNVQQQQLAYQQ 1658
Human 1203 SMVSRGMTGNIGGQFGTGI---NPQMQQNVFQY---------PGAGMVPQGEA-----NFAPSL- 1249
..|..| |.....||:.. :|.||.:..|: || |.:|.|.| ...|.|
Fly 1659 QQVGDG--GRSNTPFGSNSGMQSPGMQNSPQQWGSGGGGGGGPG-GPLPSGNAGRTLQQHNPMLI 1720
Human 1250 -----------------------SPGSSMVPMPIPPPQSSLLQQ------------TPPAS--GY 1277
||| ::.|...|..|::|.:| ||..| |:
Fly 1721 AQLQGVSPYNARQYQQNQRRGLNSPG-AVGPGGNPAAQAALQRQNSFQGQGGGGATTPDGSGVGF 1784
Human 1278 QSPDMKAWQQGAIGNN-NVFS--------------QAVQNQP-TP---AQPGVYNNMSITVSMAG 1323
..| |...|.| |||. ||.|:.| :| :.||..||.. .|.|.
Fly 1785 GGP------QSPYGTNVNVFQQQQLQRLQRQGSVPQATQHLPGSPRFGSSPGSSNNTD--SSAAA 1841
Human 1324 GNTNVQNMNPMMAQMQMSSLQ----MPGMNTVCPEQINDPALRHTG 1365
||...|.......|.|....| |.|: ::.|.....||:...|
Fly 1842 GNQQQQQQQQQQQQQQHQQQQHQQLMNGL-SMSPHPHPHPAMMGVG 1886
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