DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment OASL and F14D2.11

DIOPT Version :9

Sequence 1:	NP_003724.1	Gene:	OASL / 8638	HGNCID:	8090	Length:	514	Species:	Homo sapiens
Sequence 2:	NP_494511.2	Gene:	F14D2.11 / 184461	WormBaseID:	WBGene00017459	Length:	195	Species:	Caenorhabditis elegans

Alignment Length:	184	Identity:	32/184 - (17%)
Similarity:	61/184 - (33%)	Gaps:	43/184 - (23%)

- Green bases have known domain annotations that are detailed below.

Human   332 QDCC--YDNRENPISSWNVKRARDIHLTVEQRGYPDFNLIVNPYEPIRKVKEKIRRT----RGYS 390
            |.||  ...|::.....|.....::|...:.:     ..::.....|||..:.::.|    ....
Worm    38 QKCCEKISKRQDAQDEINTSILDELHKIQKNQ-----KKLLEEVGAIRKEVDSMKATTVKENEVK 97

Human   391 GLQRLSFQVPGSERQLLSSRCSLAKYGIFSHTHIYLLETIPSEIQVFVKNPDGGSYAYAINPNSF 455
            ..::||.      .::|..||...|                   ...:||.....:.|.:..|..
Worm    98 DDRKLSL------NEMLRKRCLQVK-------------------NTKMKNSSMPKFQYFVRLNGK 137

Human   456 ILGLKQQIED--QQGLPK-----KQQQLEFQGQVLQDWLGLGIYGIQDSDTLIL 502
            ...|.....|  :||..:     :..::.:.|:.|.|.:..|.|.|.::.|:.|
Worm   138 TRTLNVNASDTVEQGKMQLCHNARSTRMSYGGKPLSDQITFGEYNISNNSTMDL 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
OASL	NP_003724.1	NT_2-5OAS_ClassI-CCAase	29..212	CDD:143390
		OAS1_C	168..351	CDD:313619	5/20 (25%)
		OASL_repeat1	354..433	CDD:176406	11/82 (13%)
		ubiquitin	436..506	CDD:306702	16/74 (22%)
F14D2.11	NP_494511.2	Ubiquitin_like_fold	128..195	CDD:391949	14/64 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D275600at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910