Protein Alignment RNASET2 and RNaseX25

DIOPT Version :10

• Sequence 1: NP_003721.2
• Gene: RNASET2 / 8635
• HGNCID: 21686
• Length: 256
• Species: Homo sapiens
• Sequence 2: NP_523966.2
• Gene: RNaseX25 / 38885
• FlyBaseID: FBgn0010406
• Length: 325
• Species: Drosophila melanogaster
• Alignment Length: 257
• Identity: 74/257 - (28%)
• Similarity: 113/257 - (43%)
• Gaps: 35/257 - (13%)

Human    25 DKRLRD--------NHEWKKLIMVQHWPETVC-----EKIQNDCRDP--PDYWTIHGLWPDK--- 71
            |..|:|        :|.|..||..|.||.|.|     |....:|..|  .::|||||:||.|
  Fly    59 DDSLQDSSREMSVQDHNWDVLIFTQQWPVTTCYHWREENPDQECSLPQKKEFWTIHGIWPTKLHQ 123

Human    72 --SEGCNRSWPFNLEEIKDLLPEMRAYWPDVIHSFPNRSRFWKHEWEKHGTCAAQVDALNSQKKY 134
              ...||.|..|:..::..:...:..:||| :....:....|||||:||||||..|:.|:::.||
  Fly   124 MGPNFCNNSANFDPSKLNPIEDRLETFWPD-LKGMDSTEWLWKHEWQKHGTCAMLVEELDNELKY 187

Human   135 FGRSLELYRELDLNSVLLKLGIKPSINYYQVADFKDALARVYGVIPKIQCLPPSQDEEVQTIGQI 199
            |.:.|....|..::.:|....|.|..| ..||...:|:.:..|..|.|.||...: ..:..:.:|
  Fly   188 FEQGLTWREEYIMSRILDASDIHPDSN-NTVAAINNAIVKALGKNPSIHCLYDGK-HGISYLSEI 250

Human   200 ELCLTKQDQQLQNCTEPGEQPSPKQEVWLANGAAESRGLRVCEDG-----PVFYPPPKKTKH 256
            .:|.:| ..:|.:|  .|.:......|.:..|..    :..|..|     |...||.::..|
  Fly   251 RICFSK-SLELIDC--DGIKQGDAVPVGVPGGTI----ITNCHIGSLVHYPSLVPPLQRKSH 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RNASET2	NP_003721.2	RNase_T2_euk	34..227	CDD:238512	62/204 (30%)
RNaseX25	NP_523966.2	Ribonuclease_T2	76..263	CDD:459812	60/190 (32%)