Protein Alignment RUNX1T1 and Runx1t1

DIOPT Version :10

• Sequence 1: NP_001185608.1
• Gene: RUNX1T1 / 862
• HGNCID: 1535
• Length: 663
• Species: Homo sapiens
• Sequence 2: XP_006537631.1
• Gene: Runx1t1 / 12395
• MGIID: 104793
• Length: 627
• Species: Mus musculus
• Alignment Length: 575
• Identity: 571/575 - (99%)
• Similarity: 572/575 - (99%)
• Gaps: 0/575 - (0%)

Human    89 DRTEKHSTMPDSPVDVKTQSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPP 153
            |||||||||||||||||||||||||.|||||||||||||||||||||||||||||||||||||||
Mouse    53 DRTEKHSTMPDSPVDVKTQSRLTPPAMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPP 117

Human   154 NGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNST 218
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   118 NGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNST 182

Human   219 LTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTT 283
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   183 LTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTT 247

Human   284 SPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGL 348
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   248 SPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGL 312

Human   349 PHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEW 413
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   313 PHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEW 377

Human   414 KHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGGSSSSHSRQQSPV 478
            ||||||||||||||||||||||||||||||||||||||||||||||||||||.||||||||||||
Mouse   378 KHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGSSSSSHSRQQSPV 442

Human   479 NPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITTERA 543
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   443 NPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITTERA 507

Human   544 KMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHH 608
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   508 KMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHH 572

Human   609 ICGQTLQAQQQGDTPAVSSSVTPNSGAGSPMDTPPAATPRSTTPGTPSTIETTPR 663
            ||||||||.||||||||||||||:|||||||||||||||||||||||||||||||
Mouse   573 ICGQTLQAPQQGDTPAVSSSVTPSSGAGSPMDTPPAATPRSTTPGTPSTIETTPR 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RUNX1T1	NP_001185608.1	TAFH	181..270	CDD:462195	88/88 (100%)
		NHR2	396..462	CDD:430219	65/65 (100%)
		NtpE	502..>556	CDD:441000	53/53 (100%)
		zf-MYND	574..610	CDD:460312	35/35 (100%)
Runx1t1	XP_006537631.1	TAFH	145..234	CDD:462195	88/88 (100%)
		NHR2	360..426	CDD:430219	65/65 (100%)
		NtpE	466..>520	CDD:441000	53/53 (100%)
		zf-MYND	538..574	CDD:460312	35/35 (100%)