Protein Alignment RUNX1T1 and runx1t1

DIOPT Version :10

• Sequence 1: NP_001185608.1
• Gene: RUNX1T1 / 862
• HGNCID: 1535
• Length: 663
• Species: Homo sapiens
• Sequence 2: XP_004915205.1
• Gene: runx1t1 / 100491944
• XenbaseID: XB-GENE-481238
• Length: 585
• Species: Xenopus tropicalis
• Alignment Length: 575
• Identity: 557/575 - (96%)
• Similarity: 567/575 - (98%)
• Gaps: 0/575 - (0%)

Human    89 DRTEKHSTMPDSPVDVKTQSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPP 153
            |||||..||||||||||||||||||||||||||||.|||||||||||||||||||||||||||||
 Frog    11 DRTEKRCTMPDSPVDVKTQSRLTPPTMPPPPTTQGGPRTSSFTPTTLTNGTSHSPTALNGAPSPP 75

Human   154 NGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNST 218
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog    76 NGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNST 140

Human   219 LTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTT 283
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   141 LTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTT 205

Human   284 SPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGL 348
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:|||||
 Frog   206 SPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSFQPNGL 270

Human   349 PHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEW 413
            |||||||||||||||||||||||||||||:|||||||||||||||||||||||||||||||||||
 Frog   271 PHPTPPPPQHYRLDDMAIAHHYRDSYRHPNHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEW 335

Human   414 KHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGGSSSSHSRQQSPV 478
            |||||||||||||||||||||||||||||||||||||||||||||||||||..||||||||||||
 Frog   336 KHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGSSSSSSHSRQQSPV 400

Human   479 NPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITTERA 543
            ||:||.|::||||||||||||||||||||||||||||||||||||||||||||||||:|||||||
 Frog   401 NPEPVPLESHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHEMITTERA 465

Human   544 KMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHH 608
            ||||||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||||
 Frog   466 KMERTVAEAKRQAAEDALSVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHH 530

Human   609 ICGQTLQAQQQGDTPAVSSSVTPNSGAGSPMDTPPAATPRSTTPGTPSTIETTPR 663
            ||||||||||||:||||||||||:||||||:|||||||||||||||||||||..|
 Frog   531 ICGQTLQAQQQGETPAVSSSVTPSSGAGSPIDTPPAATPRSTTPGTPSTIETAAR 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RUNX1T1	NP_001185608.1	TAFH	181..270	CDD:462195	88/88 (100%)
		NHR2	396..462	CDD:430219	65/65 (100%)
		NtpE	502..>556	CDD:441000	52/53 (98%)
		zf-MYND	574..610	CDD:460312	35/35 (100%)
runx1t1	XP_004915205.1	TAFH	103..192	CDD:462195	88/88 (100%)
		NHR2	318..384	CDD:430219	65/65 (100%)
		NtpE	424..>478	CDD:441000	52/53 (98%)
		zf-MYND	496..532	CDD:460312	35/35 (100%)